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yvon Trottier
yvon Trottier
Institut de Genetique et de Biologie moleculaire et cellulaire
在 igbmc.fr 的电子邮件经过验证
标题
引用次数
引用次数
年份
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, ...
Cell 87 (3), 493-506, 1996
35851996
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3
HL Paulson, MK Perez, Y Trottier, JQ Trojanowski, SH Subramony, ...
Neuron 19 (2), 333-344, 1997
10101997
Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats
G Imbert, F Saudou, G Yvert, D Devys, Y Trottier, JM Garnier, C Weber, ...
Nature genetics 14 (3), 285-291, 1996
10071996
Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes
V Campuzano, L Montermini, Y Lutz, L Cova, C Hindelang, S Jiralerspong, ...
Human molecular genetics 6 (11), 1771-1780, 1997
9031997
Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias
Y Trottier, Y Lutz, G Stevanin, G Imbert, D Devys, G Cancel, F Saudou, ...
Nature 378 (6555), 403-406, 1995
7871995
Phenotypic characterization of individuals with 30–40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals …
DC Rubinsztein, J Leggo, R Coles, E Almqvist, V Biancalana, ...
American journal of human genetics 59 (1), 16, 1996
7001996
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
Y Trottier, D Devys, G Imbert, F Saudou, I An, Y Lutz, C Weber, Y Agid, ...
Nature genetics 10 (1), 104-110, 1995
5671995
Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions
A Lunkes, KS Lindenberg, L Ben-Haı̈em, C Weber, D Devys, ...
Molecular cell 10 (2), 259-269, 2002
5022002
Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions
M Holmberg, C Duyckaerts, A Dürr, G Cancel, I Gourfinkel-An, P Damier, ...
Human molecular genetics 7 (5), 913-918, 1998
4261998
Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease
C Landles, K Sathasivam, A Weiss, B Woodman, H Moffitt, S Finkbeiner, ...
Journal of Biological Chemistry 285 (12), 8808-8823, 2010
3592010
Instability of CAG repeats in Huntington's disease: relation to parental transmission and age of onset.
Y Trottier, V Biancalana, JL Mandel
Journal of medical genetics 31 (5), 377-382, 1994
2991994
An isoform of ataxin‐3 accumulates in the nucleus of neuronal cells in affected brain regions of SCA3 patients
T Schmidt, GB Landwehrmeyer, I Schmitt, Y Trottier, G Auburger, ...
Brain pathology 8 (4), 669-679, 1998
2561998
Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins
L Masino, G Kelly, K Leonard, Y Trottier, A Pastore
Febs Letters 513 (2-3), 267-272, 2002
1842002
Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction
D Helmlinger, S Hardy, G Abou-Sleymane, A Eberlin, AB Bowman, ...
PLoS biology 4 (3), e67, 2006
1822006
Domain architecture of the polyglutamine protein ataxin‐3: a globular domain followed by a flexible tail
L Masino, V Musi, RP Menon, P Fusi, G Kelly, TA Frenkiel, Y Trottier, ...
FEBS letters 549 (1-3), 21-25, 2003
1602003
Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice
AV Goula, BR Berquist, DM Wilson III, VC Wheeler, Y Trottier, K Merienne
PLoS genetics 5 (12), e1000749, 2009
1582009
Heterogeneous intracellular localization and expression of ataxin-3
Y Trottier, G Cancel, I An-Gourfinkel, Y Lutz, C Weber, A Brice, E Hirsch, ...
Neurobiology of disease 5 (5), 335-347, 1998
1411998
An expanded CAG repeat sequence in spinocerebellar ataxia type 7.
K Lindblad, ML Savontaus, G Stevanin, M Holmberg, K Digre, C Zander, ...
Genome Research 6 (10), 965-971, 1996
1311996
Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient
FAC Klein, A Pastore, L Masino, G Zeder-Lutz, H Nierengarten, ...
Journal of molecular biology 371 (1), 235-244, 2007
1052007
High Level Expression of Expanded Full-length Ataxin-3 In Vitro Causes Cell Death and Formation of Intranuclear Inclusions in Neuronal Cells
BO Evert, U Wüllner, JB Schulz, M Weller, P Groscurth, Y Trottier, A Brice, ...
Human molecular genetics 8 (7), 1169-1176, 1999
1041999
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