Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells JK Richer, BM Jacobsen, NG Manning, MG Abel, KB Horwitz, DM Wolf Journal of Biological Chemistry 277 (7), 5209-5218, 2002 | 720 | 2002 |
Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide DR Cochrane, S Bernales, BM Jacobsen, DM Cittelly, EN Howe, ... Breast Cancer Research 16, 1-19, 2014 | 439 | 2014 |
Progesterone receptors, their isoforms and progesterone regulated transcription BM Jacobsen, KB Horwitz Molecular and cellular endocrinology 357 (1-2), 18-29, 2012 | 289 | 2012 |
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination C Korch, MA Spillman, TA Jackson, BM Jacobsen, SK Murphy, BA Lessey, ... Gynecologic oncology 127 (1), 241-248, 2012 | 287 | 2012 |
Multiple Molecular Subtypes of Triple-Negative Breast Cancer Critically Rely on Androgen Receptor and Respond to Enzalutamide In Vivo VN Barton, NC D'Amato, MA Gordon, HT Lind, NS Spoelstra, BL Babbs, ... Molecular cancer therapeutics 14 (3), 769-778, 2015 | 256 | 2015 |
Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding … K Shin Voo, DL Carlone, BM Jacobsen, A Flodin, DG Skalnik Molecular and cellular biology 20 (6), 2108-2121, 2000 | 249 | 2000 |
Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology BM Jacobsen, SA Schittone, JK Richer, KB Horwitz Molecular Endocrinology 19 (3), 574-587, 2005 | 200 | 2005 |
Cooperative dynamics of AR and ER activity in breast cancer NC D'Amato, MA Gordon, B Babbs, NS Spoelstra, KT Carson Butterfield, ... Molecular cancer research 14 (11), 1054-1067, 2016 | 142 | 2016 |
Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4 DM Cittelly, J Finlay-Schultz, EN Howe, NS Spoelstra, SD Axlund, ... Oncogene 32 (20), 2555-2564, 2013 | 138 | 2013 |
New human breast cancer cells to study progesterone receptor isoform ratio effects and ligand-independent gene regulation BM Jacobsen, JK Richer, SA Schittone, KB Horwitz Journal of Biological Chemistry 277 (31), 27793-27800, 2002 | 117 | 2002 |
Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium BM Jacobsen, JC Harrell, P Jedlicka, VF Borges, M Varella-Garcia, ... Cancer research 66 (16), 8274-8279, 2006 | 104 | 2006 |
Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure GS Takimoto, L Tung, H Abdel-Hafiz, MG Abel, CA Sartorius, JK Richer, ... The Journal of steroid biochemistry and molecular biology 85 (2-5), 209-219, 2003 | 102 | 2003 |
Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a J Finlay-Schultz, DM Cittelly, P Hendricks, P Patel, P Kabos, BM Jacobsen, ... Oncogene 34 (28), 3676-3687, 2015 | 92 | 2015 |
The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells RP Ghatge, BM Jacobsen, SA Schittone, KB Horwitz Breast cancer research 7, 1-15, 2005 | 88 | 2005 |
Progesterone receptor action: translating studies in breast cancer models to clinical insights CA Lange, CA Sartorius, H Abdel-Hafiz, MA Spillman, KB Horwitz, ... Innovative endocrinology of cancer, 94-111, 2008 | 85 | 2008 |
Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxel IR Schlaepfer, CA Hitz, MA Gijón, BC Bergman, RH Eckel, BM Jacobsen Molecular and cellular endocrinology 363 (1-2), 111-121, 2012 | 83 | 2012 |
Progestin regulated miRNAs that mediate progesterone receptor action in breast cancer DR Cochrane, BM Jacobsen, KD Connaghan, EN Howe, DL Bain, ... Molecular and cellular endocrinology 355 (1), 15-24, 2012 | 78 | 2012 |
Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis MA Spillman, NG Manning, WW Dye, CA Sartorius, MD Post, JC Harrell, ... Cancer research 70 (21), 8927-8936, 2010 | 77 | 2010 |
Quantitative analysis of gene regulation by seven clinically relevant progestins suggests a highly similar mechanism of action through progesterone receptors in T47D breast … JD Bray, S Jelinsky, R Ghatge, JA Bray, C Tunkey, K Saraf, BM Jacobsen, ... The Journal of Steroid Biochemistry and Molecular Biology 97 (4), 328-341, 2005 | 77 | 2005 |
Loss of E-cadherin Enhances IGF1–IGF1R pathway activation and sensitizes breast cancers to anti-IGF1R/InsR inhibitors AM Nagle, KM Levine, N Tasdemir, JA Scott, K Burlbaugh, J Kehm, ... Clinical Cancer Research 24 (20), 5165-5177, 2018 | 75 | 2018 |