Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle E De Fabiani, N Mitro, F Gilardi, D Caruso, G Galli, M Crestani Journal of Biological Chemistry 278 (40), 39124-39132, 2003 | 254 | 2003 |
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue A Galmozzi, N Mitro, A Ferrari, E Gers, F Gilardi, C Godio, G Cermenati, ... diabetes 62 (3), 732-742, 2013 | 251 | 2013 |
Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles G Le Martelot, D Canella, L Symul, E Migliavacca, F Gilardi, R Liechti, ... PLoS Biol 10 (11), e1001442, 2012 | 212 | 2012 |
Quantifying ChIP-seq data: a spiking method providing an internal reference for sample-to-sample normalization N Bonhoure, G Bounova, D Bernasconi, V Praz, F Lammers, D Canella, ... Genome research 24 (7), 1157-1168, 2014 | 157 | 2014 |
Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic … R Montanari, F Saccoccia, E Scotti, M Crestani, C Godio, F Gilardi, ... Journal of medicinal chemistry 51 (24), 7768-7776, 2008 | 128 | 2008 |
From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions T Caputo, F Gilardi, B Desvergne FEBS letters 591 (19), 3061-3088, 2017 | 118 | 2017 |
Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-κB signaling M Dell’Agli, R Fagnani, GV Galli, O Maschi, F Gilardi, S Bellosta, ... Journal of agricultural and food chemistry 58 (4), 2246-2252, 2010 | 94 | 2010 |
The pharmacological exploitation of cholesterol 7α-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol F Gilardi, N Mitro, C Godio, E Scotti, D Caruso, M Crestani, E De Fabiani Pharmacology & therapeutics 116 (3), 449-472, 2007 | 89 | 2007 |
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning A Ferrari, R Longo, E Fiorino, R Silva, N Mitro, G Cermenati, F Gilardi, ... Nature communications 8 (1), 93, 2017 | 82 | 2017 |
LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport M Crestani, E De Fabiani, D Caruso, N Mitro, F Gilardi, AB Vigil Chacon, ... Biochemical Society Transactions 32 (1), 92-96, 2004 | 76 | 2004 |
Transcriptional regulatory logic of the diurnal cycle in the mouse liver JA Sobel, I Krier, T Andersin, S Raghav, D Canella, F Gilardi, AS Kalantzi, ... PLoS biology 15 (4), e2001069, 2017 | 74 | 2017 |
Insights in the regulation of cholesterol 7α‐hydroxylase gene reveal a target for modulating bile acid synthesis N Mitro, C Godio, E De Fabiani, E Scotti, A Galmozzi, F Gilardi, D Caruso, ... Hepatology 46 (3), 885-897, 2007 | 74 | 2007 |
A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver D Canella, D Bernasconi, F Gilardi, G LeMartelot, E Migliavacca, V Praz, ... Genome research 22 (4), 666-680, 2012 | 65 | 2012 |
SOCS3 Transactivation by PPARγ Prevents IL-17–Driven Cancer Growth H Berger, F Végran, M Chikh, F Gilardi, S Ladoire, H Bugaut, G Mignot, ... Cancer research 73 (12), 3578-3590, 2013 | 61 | 2013 |
Linking epigenetics to lipid metabolism: focus on histone deacetylases A Ferrari, E Fiorino, M Giudici, F Gilardi, A Galmozzi, N Mitro, G Cermenati, ... Molecular membrane biology 29 (7), 257-266, 2012 | 59 | 2012 |
Structural insight into peroxisome proliferator-activated receptor γ binding of two ureidofibrate-like enantiomers by molecular dynamics, cofactor interaction analysis, and … G Pochetti, N Mitro, A Lavecchia, F Gilardi, N Besker, E Scotti, M Aschi, ... Journal of medicinal chemistry 53 (11), 4354-4366, 2010 | 56 | 2010 |
Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production E Corsini, B Viviani, S Birindelli, F Gilardi, A Torri, I Codecà, L Lucchi, ... Toxicology and applied pharmacology 212 (2), 89-98, 2006 | 56 | 2006 |
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity L Porcelli, F Gilardi, A Laghezza, L Piemontese, N Mitro, A Azzariti, ... Journal of medicinal chemistry 55 (1), 37-54, 2012 | 55 | 2012 |
Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signals F Gilardi, E Migliavacca, A Naldi, M Baruchet, D Canella, G Le Martelot, ... PLoS Genet 10 (3), e1004155, 2014 | 54 | 2014 |
Delayed hair follicle morphogenesis and hair follicle dystrophy in a lipoatrophy mouse model of Pparg total deletion C Sardella, C Winkler, L Quignodon, JA Hardman, B Toffoli, ... Journal of Investigative Dermatology 138 (3), 500-510, 2018 | 48 | 2018 |