| Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart DF Dai, PP Karunadharma, YA Chiao, N Basisty, D Crispin, EJ Hsieh, ... Aging cell 13 (3), 529-539, 2014 | 338 | 2014 |
| Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration PP Karunadharma, CL Nordgaard, TW Olsen, DA Ferrington Investigative ophthalmology & visual science 51 (11), 5470-5479, 2010 | 259 | 2010 |
| Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration CL Nordgaard, PP Karunadharma, X Feng, TW Olsen, DA Ferrington Investigative ophthalmology & visual science 49 (7), 2848-2855, 2008 | 209 | 2008 |
| Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects PP Karunadharma, N Basisty, DF Dai, YA Chiao, EK Quarles, EJ Hsieh, ... Aging cell 14 (4), 547-557, 2015 | 104 | 2015 |
| Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease M Eshraghi, PP Karunadharma, J Blin, N Shahani, EP Ricci, A Michel, ... Nature communications 12 (1), 1461, 2021 | 88 | 2021 |
| Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration DA Ferrington, RJ Kapphahn, MM Leary, SR Atilano, MR Terluk, ... Experimental eye research 145, 269-277, 2016 | 78 | 2016 |
| Age modifies respiratory complex I and protein homeostasis in a muscle type‐specific manner SE Kruse, PP Karunadharma, N Basisty, R Johnson, RP Beyer, ... Aging Cell 15 (1), 89-99, 2016 | 77 | 2016 |
| Topograph, a software platform for precursor enrichment corrected global protein turnover measurements EJ Hsieh, NJ Shulman, DF Dai, ES Vincow, PP Karunadharma, ... Molecular & Cellular Proteomics 11 (11), 1468-1474, 2012 | 68 | 2012 |
| Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments PP Karunadharma, N Basisty, YA Chiao, DF Dai, R Drake, N Levy, ... The FASEB Journal 29 (8), 3582, 2015 | 65 | 2015 |
| Mining naive rabbit antibody repertoires by phage display for monoclonal antibodies of therapeutic utility H Peng, T Nerreter, J Chang, J Qi, X Li, P Karunadharma, GJ Martinez, ... Journal of molecular biology 429 (19), 2954-2973, 2017 | 52 | 2017 |
| A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020 MH Tran, H Park, CL Nobles, P Karunadharma, L Pan, G Zhong, H Wang, ... Molecular Therapy-Nucleic Acids 24, 40-53, 2021 | 27 | 2021 |
| Stable isotope labeling reveals novel insights into ubiquitin-mediated protein aggregation with age, calorie restriction, and rapamycin treatment NB Basisty, Y Liu, J Reynolds, PP Karunadharma, DF Dai, J Fredrickson, ... The Journals of Gerontology: Series A 73 (5), 561-570, 2018 | 27 | 2018 |
| Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure DF Dai, Y Liu, N Basisty, P Karunadharma, SG Dastidar, YA Chiao, ... Geroscience 41, 847-860, 2019 | 17 | 2019 |
| Reprogramming of the heavy-chain CDR3 regions of a human antibody repertoire T Ou, W He, BD Quinlan, Y Guo, MH Tran, P Karunadharma, H Park, ... Molecular Therapy 30 (1), 184-197, 2022 | 10 | 2022 |
| Dissecting Regulators of Aging and Age‐Related Macular Degeneration in the Retinal Pigment Epithelium PP Karunadharma, RJ Kapphahn, MR Stahl, TW Olsen, DA Ferrington Oxidative Medicine and Cellular Longevity 2022 (1), 6009787, 2022 | 9 | 2022 |
| Global ribosome profiling reveals that mutant huntingtin stalls ribosomes and represses protein synthesis independent of fragile X mental retardation protein M Eshraghi, P Karunadharma, J Blin, N Shahani, E Ricci, A Michel, ... BioRxiv, 629667, 2019 | 8 | 2019 |
| The chromatin regulator Mll1 supports T follicular helper cell differentiation by controlling expression of Bcl6, LEF-1, and TCF-1 S Bélanger, S Haupt, CE Faliti, A Getzler, J Choi, H Diao, ... The Journal of Immunology 210 (11), 1752-1760, 2023 | 6 | 2023 |
| Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression O Rivera, M Sharma, S Dagar, N Shahani, UN Ramĺrez-Jarquĺn, ... Cellular and Molecular Life Sciences 81 (1), 169, 2024 | 4 | 2024 |
| Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny H Diao, R Chen, SM Tsuda, D Wang, MA Frederick, J Kim, ... bioRxiv, 2021.08. 11.456014, 2021 | 1 | 2021 |
| No association between cataract surgery and mitochondrial DNA damage with age-related macular degeneration in human donor eyes KR Armbrust, PP Karunadharma, MR Terluk, RJ Kapphahn, TW Olsen, ... PloS one 16 (10), e0258803, 2021 | | 2021 |
Michael MacCossProfessor of Genome Sciences, University of Washington在 uw.edu 的电子邮件经过验证
