Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a … CS Latimer, BT Burke, NF Liachko, HN Currey, MD Kilgore, LE Gibbons, ... Acta neuropathologica communications 7, 1-24, 2019 | 91 | 2019 |
Sertraline, paroxetine, and chlorpromazine are rapidly acting anthelmintic drugs capable of clinical repurposing JC Weeks, WM Roberts, C Leasure, BM Suzuki, KJ Robinson, H Currey, ... Scientific reports 8 (1), 975, 2018 | 79 | 2018 |
The phosphatase calcineurin regulates pathological TDP-43 phosphorylation NF Liachko, AD Saxton, PJ McMillan, TJ Strovas, HN Currey, LM Taylor, ... Acta neuropathologica 132, 545-561, 2016 | 59 | 2016 |
TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans CS Latimer, JG Stair, JC Hincks, HN Currey, TD Bird, CD Keene, ... Disease Models & Mechanisms 15 (4), dmm049323, 2022 | 28 | 2022 |
ARENA-based activity profiling of tau and TDP-43 transgenic C. elegans HN Currey, A Malinkevich, P Melquist, NF Liachko microPublication Biology 2020, 2020 | 10 | 2020 |
Evaluation of motor impairment in C. elegans models of amyotrophic lateral sclerosis HN Currey, NF Liachko JoVE (Journal of Visualized Experiments), e62699, 2021 | 7 | 2021 |
Sertraline, paroxetine, and chlorpromazine are rapidly acting anthelmintic drugs capable of clinical repurposing. Sci Rep 8 JC Weeks, WM Roberts, C Leasure, BM Suzuki, KJ Robinson, H Currey, ... | 6 | 2018 |
Transcriptomic evaluation of tau and TDP-43 synergism shows tauopathy predominance and reveals potential modulating targets VS Jadhav, JG Stair, RJ Eck, SN Smukowski, HN Currey, LG Toscano, ... Neurobiology of disease 193, 106441, 2024 | 3 | 2024 |
Transgenic Dendra2:: tau expression allows in vivo monitoring of tau proteostasis in Caenorhabditis elegans M Han, A Saxton, H Currey, SM Waldherr, NF Liachko, BC Kraemer Disease Models & Mechanisms 17 (3), 2024 | 3 | 2024 |
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity HN Currey, BC Kraemer, NF Liachko Micropublication Biology 2023, 2023 | 3 | 2023 |
Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis L Garcia-Toscano, HN Currey, JC Hincks, JG Stair, NJ Lehrbach, ... PLoS genetics 20 (12), e1011518, 2024 | | 2024 |
sut-2 modifies tau and TDP-43 synergistic phenotypes in a C. elegans model of combined proteotoxicity CS Latimer, J Stair, H Currey, JC Hincks, CD Keene, BC Kraemer, ... AAIC Neuroscience Next, 2020 | | 2020 |
ARENA-based activity profiling of tau and TDP-43 transgenic C. elegans. microPublication Biology HN Currey, A Malinkevich, P Melquist, NF Liachko | | 2020 |
Resilience and resistance to AD pathology correlate with absence of pTDP-43 pathology and lower cortical pTau burden in a community-based cohort C Latimer, B Burke, N Liachko, H Currey, M Kilgore, L Gibbons, ... JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 78 (6), 550-550, 2019 | | 2019 |
A CRISPR/Cas9-generated cdc-7 loss of function mutation does not cause temperature-dependent fertility defects H Currey, N Liachko Micropublication Biology 2019, 2019 | | 2019 |
The effects of silencing insulins on the morphology and function of both healthy and degenerate mechanosensory neurons in the C. elegans aging model S Hunter, H Currey | | 2013 |