Human BRCA1–BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection RM Densham, AJ Garvin, HR Stone, J Strachan, RA Baldock, ... Nature structural & molecular biology 23 (7), 647-655, 2016 | 287 | 2016 |
The proteasomal de‐ubiquitinating enzyme POH1 promotes the double‐strand DNA break response LR Butler, RM Densham, J Jia, AJ Garvin, HR Stone, V Shah, D Weekes, ... The EMBO journal 31 (19), 3918-3934, 2012 | 166 | 2012 |
The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair AJ Garvin, RM Densham, SA Blair‐Reid, KM Pratt, HR Stone, D Weekes, ... EMBO reports 14 (11), 975-983, 2013 | 113 | 2013 |
Isomerization of BRCA1–BARD1 promotes replication fork protection M Daza-Martin, K Starowicz, M Jamshad, S Tye, GE Ronson, HL MacKay, ... Nature 571 (7766), 521-527, 2019 | 110 | 2019 |
SUMO, a small, but powerful, regulator of double-strand break repair AJ Garvin, JR Morris Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 78 | 2017 |
Sunlight Generates Multiple Tryptophan Photoproducts Eliciting High Efficacy CYP1A Induction in Chick Hepatocytes and In Vivo S Diani-Moore, E Labitzke, R Brown, A Garvin, L Wong, AB Rifkind Toxicological Sciences 90 (1), 96-110, 2006 | 76 | 2006 |
A ChIP–chip approach reveals a novel role for transcription factor IRF1 in the DNA damage response M Frontini, M Vijayakumar, A Garvin, N Clarke Nucleic acids research 37 (4), 1073-1085, 2009 | 73 | 2009 |
The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms AJ Garvin, AK Walker, RM Densham, AS Chauhan, HR Stone, HL Mackay, ... Genes & Development 33 (5-6), 333-347, 2019 | 41 | 2019 |
SUMO in the DNA double-stranded break response: similarities, differences, and cooperation with ubiquitin JR Morris, AJ Garvin Journal of molecular biology 429 (22), 3376-3387, 2017 | 34 | 2017 |
GSK3β-SCFFBXW7α mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover AJ Garvin, AHA Khalaf, A Rettino, J Xicluna, L Butler, JR Morris, ... Nucleic acids research 47 (9), 4476-4494, 2019 | 24 | 2019 |
Beyond reversal: ubiquitin and ubiquitin-like proteases and the orchestration of the DNA double strand break repair response AJ Garvin Biochemical Society Transactions 47 (6), 1881-1893, 2019 | 18 | 2019 |
Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting GE Ronson, K Starowicz, EJ Anthony, AL Piberger, LC Clarke, AJ Garvin, ... Nature Communications 14 (1), 7834, 2023 | 10 | 2023 |
SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate AJ Garvin, AJ Lanz, JR Morris Scientific Reports 12 (1), 21343, 2022 | 7 | 2022 |
Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation AS Chauhan, AJ Garvin, M Jamshad, JR Morris bioRxiv, 2022.03. 22.485326, 2022 | 2 | 2022 |
SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect SUMO conjugate types AJ Garvin, AJ Lanz, JR Morris bioRxiv, 2022.03. 19.484974, 2022 | 2 | 2022 |
SUMO and the DNA damage response JS Bhachoo, AJ Garvin Biochemical Society Transactions 52 (2), 773, 2024 | 1 | 2024 |
RAD52 underlies the synthetic-lethal relationship between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta loss K Starowicz, G Ronson, E Anthony, L Clarke, AJ Garvin, AD Beggs, ... bioRxiv, 2022.03. 20.485027, 2022 | 1 | 2022 |
SUMO4 promotes SUMO deconjugation required for DNA double-strand break repair AJ Garvin, AJ Lanz, K Starowicz, GE Ronson, MJW Mackintosh, ... bioRxiv, 2022.03. 23.485504, 2022 | | 2022 |
Modification of the SUMO activating enzyme subunit SAE2 directs SUMO isoform bias required for mitotic fidelity AK Walker, AJ Lanz, M Jamshad, AJ Garvin, P Wotherspoon, BF Cooper, ... bioRxiv, 2022.03. 18.484840, 2022 | | 2022 |
GSK3β-SCFFBXW7 mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover AJ Garvin, AHA Khalaf, A Rettino, J Xicluna, L Butler, JR Morris, ... bioRxiv, 481911, 2018 | | 2018 |