HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types A Zirkel, M Nikolic, K Sofiadis, JP Mallm, CA Brackley, H Gothe, ... Molecular cell 70 (4), 730-744. e6, 2018 | 200 | 2018 |
Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations HJ Gothe, BAM Bouwman, EG Gusmao, R Piccinno, G Petrosino, ... Molecular cell 75 (2), 267-283. e12, 2019 | 146 | 2019 |
Human brain organoids assemble functionally integrated bilateral optic vesicles E Gabriel, W Albanna, G Pasquini, A Ramani, N Josipovic, A Mariappan, ... Cell stem cell 28 (10), 1740-1757. e8, 2021 | 124 | 2021 |
RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis S Zhang, N Übelmesser, N Josipovic, G Forte, JA Slotman, M Chiang, ... Science advances 7 (43), eabg8205, 2021 | 87 | 2021 |
Ageing-associated changes in transcriptional elongation influence longevity C Debès, A Papadakis, S Grönke, Ö Karalay, LS Tain, A Mizi, ... Nature 616 (7958), 814-821, 2023 | 81 | 2023 |
Redundant and specific roles of cohesin STAG subunits in chromatin looping and transcriptional control V Casa, MM Gines, EG Gusmao, JA Slotman, A Zirkel, N Josipovic, E Oole, ... Genome Research 30 (4), 515-527, 2020 | 70 | 2020 |
HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence K Sofiadis, N Josipovic, M Nikolic, Y Kargapolova, N Übelmesser, ... Molecular systems biology 17 (6), e9760, 2021 | 62 | 2021 |
Cilium induction triggers differentiation of glioma stem cells G Goranci-Buzhala, A Mariappan, L Ricci-Vitiani, N Josipovic, S Pacioni, ... Cell reports 36 (10), 2021 | 31 | 2021 |
GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73 ME Lalioti, M Arbi, I Loukas, K Kaplani, A Kalogeropoulou, G Lokka, ... Journal of Cell Science 132 (11), jcs228684, 2019 | 29 | 2019 |
Extracellular ATP induces graded reactive response of astrocytes and strengthens their antioxidative defense in vitro M Adzic, I Stevanovic, N Josipovic, D Laketa, I Lavrnja, IM Bjelobaba, ... Journal of Neuroscience Research 95 (4), 1053-1066, 2017 | 23 | 2017 |
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology Y Kargapolova, R Rehimi, H Kayserili, J Brühl, K Sofiadis, A Zirkel, ... Nature Communications 12 (1), 3014, 2021 | 22 | 2021 |
Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype R Wallis, N Josipovic, H Mizen, A Robles‐Tenorio, EJ Tyler, A Papantonis, ... Journal of Extracellular Vesicles 10 (4), e12041, 2021 | 12 | 2021 |
Generation of iPSC-derived human forebrain organoids assembling bilateral eye primordia E Gabriel, W Albanna, G Pasquini, A Ramani, N Josipovic, A Mariappan, ... Nature Protocols 18 (6), 1893-1929, 2023 | 6 | 2023 |
circRAB3IP modulates cell proliferation by reorganizing gene expression and mRNA processing in a paracrine manner N Josipovic, KK Ebbesen, A Zirkel, A Danieli-Mackay, C Dieterich, ... RNA 28 (11), 1481-1495, 2022 | 3 | 2022 |
HMGB1 as a rheostat of chromatin topology and RNA homeostasis on the path to senescence K Sofiadis, M Nikolic, A Zirkel, Y Kargapolova, N Josipovic, A Papadakis, ... bioRxiv, 540146, 2019 | 3 | 2019 |
Tumor vessel normalization via PFKFB3 inhibition alleviates hypoxia and increases tumor necrosis in rectal cancer upon radiotherapy M Edelmann, S Fan, T De Oliveira, T Goldhardt, D Sartorius, ... Cancer Research Communications 4 (8), 2008-2024, 2024 | 1 | 2024 |
Rapid and synchronous chemical induction of replicative‐like senescence via a small molecule inhibitor S Palikyras, K Sofiadis, A Stavropoulou, A Danieli‐Mackay, ... Aging Cell 23 (4), e14083, 2024 | 1 | 2024 |
10x Genomics Gene Expression Flex is a powerful tool for single-cell transcriptomics of xenograft models O Llora-Batlle, A Farcas, D Fransen, N Floc’h, S Talbot, A Schwiening, ... bioRxiv, 2024.01. 25.577066, 2024 | 1 | 2024 |
Chromatin reorganization, signaling responses and non-coding RNA regulators in homeostasis and senescence N Josipovic | | 2022 |
Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov G V., Sonkin D, et al. 2012. The Cancer Cell Line Encyclopedia enables … V Casa, MM Gines, EG Gusmao, JA Slotman, A Zirkel, N Josipovic, E Oole, ... DETERMINANTS OF COHESIN LOCALIZATION AND FUNCTION IN GENOME ORGANIZATION AND …, 2021 | | 2021 |