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Romain PACAUD
Romain PACAUD
Merck & Co., MRL Discovery Oncology, South San Francisco (CA), USA
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme
M Cheray, A Etcheverry, C Jacques, R Pacaud, G Bougras-Cartron, ...
Molecular cancer 19, 1-16, 2020
782020
The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures
R Pacaud, E Brocard, L Lalier, E Hervouet, FM Vallette, PF Cartron
Scientific reports 4 (1), 4230, 2014
632014
DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-) methylation of TRAF1
R Pacaud, Q Sery, L Oliver, FM Vallette, J Tost, PF Cartron
Biochimie 104, 36-49, 2014
542014
Histone H3 phosphorylation in GBM: a new rational to guide the use of kinase inhibitors in anti-GBM therapy
R Pacaud, M Cheray, A Nadaradjane, FM Vallette, PF Cartron
Theranostics 5 (1), 12, 2015
402015
Specific inhibition of one DNMT1-including complex influences tumor initiation and progression
M Cheray, R Pacaud, A Nadaradjane, FM Vallette, PF Cartron
Clinical epigenetics 5, 1-7, 2013
372013
Specific inhibition of DNMT3A/ISGF3γ interaction increases the temozolomide efficiency to reduce tumor growth
M Cheray, R Pacaud, A Nadaradjane, L Oliver, FM Vallette, PF Cartron
Theranostics 6 (11), 1988, 2016
172016
DNMT inhibitors in cancer, current treatments and future promising approach: inhibition of specific DNMT-including complexes
M Cheray, R Pacaud, E Hervouet, F M. Vallette, PF Cartron
Epigenetic Diagnosis & Therapy 1 (1), 37-48, 2015
142015
A phase Ib trial of the PI3K inhibitor alpelisib and weekly cisplatin in patients with solid tumor malignancies
ES Tsang, RR Aggarwal, MS Dhawan, EK Bergsland, EA Alvarez, ...
Cancer Research Communications 2 (7), 570-576, 2022
42022
Méthylation/déméthylation de l’ADN et expression du génome
PF Cartron, R Pacaud, G Salbert
Revue Francophone des Laboratoires 2015 (473), 37-48, 2015
42015
Clinical Applications of Histone Deacetylase Inhibitors
R Pacaud, J Garcia, S Thomas, PN Munster
Handbook of Epigenetics, 793-819, 2023
12023
Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors
R Pacaud, S Thomas, S Chaudhuri, A Lazar, LA Timmerman, PN Munster
Breast Cancer Research 27 (1), 8, 2025
2025
Synthetic Lethality Beyond BRCA: A Phase I Study of Rucaparib and Irinotecan in Metastatic Solid Tumors With Homologous Recombination-Deficiency Mutations Beyond BRCA1/2
ES Tsang, MS Dhawan, R Pacaud, S Thomas, J Grabowsky, L Wilch, ...
JCO Precision Oncology 8, e2300494, 2024
2024
A phase Ib trial of alpelisib and weekly cisplatin in patients with solid tumor malignancies.
ES Tsang, RR Aggarwal, MS Dhawan, R Pacaud, D Fattah, S Thomas, ...
Journal of Clinical Oncology 39 (15_suppl), 3134-3134, 2021
2021
Abstract PS8-13: Silicone implant based sustained localized drug delivery of fulvestrant to prevent breast cancer
PN Munster, PK Desai, N Pawlowska, E Roche, R Pacaud, MA Daud, ...
Cancer Research 81 (4_Supplement), PS8-13-PS8-13, 2021
2021
Abstract P3-11-12: Epigenetic modulation to deepen and prolong the response to PARP inhibitors
R Pacaud, M Dhawan, S Thomas, E Roche, J Garcia, N Pawlowska, ...
Cancer Research 80 (4_Supplement), P3-11-12-P3-11-12, 2020
2020
Abstract P6-21-10: Not presented
R Pacaud, S Thomas, E Roche, N Pawlowska, P Munster
Cancer Research 79 (4_Supplement), P6-21-10-P6-21-10, 2019
2019
Talazoparib and decitabine: a promising combination for BRCA-mutated cancers treatment
R Pacaud, S Thomas, E Roche, N Pawlowska, M Dhawan, P Munster
EUROPEAN JOURNAL OF CANCER 103, E28-E28, 2018
2018
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