Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme M Cheray, A Etcheverry, C Jacques, R Pacaud, G Bougras-Cartron, ... Molecular cancer 19, 1-16, 2020 | 78 | 2020 |
The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures R Pacaud, E Brocard, L Lalier, E Hervouet, FM Vallette, PF Cartron Scientific reports 4 (1), 4230, 2014 | 63 | 2014 |
DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-) methylation of TRAF1 R Pacaud, Q Sery, L Oliver, FM Vallette, J Tost, PF Cartron Biochimie 104, 36-49, 2014 | 54 | 2014 |
Histone H3 phosphorylation in GBM: a new rational to guide the use of kinase inhibitors in anti-GBM therapy R Pacaud, M Cheray, A Nadaradjane, FM Vallette, PF Cartron Theranostics 5 (1), 12, 2015 | 40 | 2015 |
Specific inhibition of one DNMT1-including complex influences tumor initiation and progression M Cheray, R Pacaud, A Nadaradjane, FM Vallette, PF Cartron Clinical epigenetics 5, 1-7, 2013 | 37 | 2013 |
Specific inhibition of DNMT3A/ISGF3γ interaction increases the temozolomide efficiency to reduce tumor growth M Cheray, R Pacaud, A Nadaradjane, L Oliver, FM Vallette, PF Cartron Theranostics 6 (11), 1988, 2016 | 17 | 2016 |
DNMT inhibitors in cancer, current treatments and future promising approach: inhibition of specific DNMT-including complexes M Cheray, R Pacaud, E Hervouet, F M. Vallette, PF Cartron Epigenetic Diagnosis & Therapy 1 (1), 37-48, 2015 | 14 | 2015 |
A phase Ib trial of the PI3K inhibitor alpelisib and weekly cisplatin in patients with solid tumor malignancies ES Tsang, RR Aggarwal, MS Dhawan, EK Bergsland, EA Alvarez, ... Cancer Research Communications 2 (7), 570-576, 2022 | 4 | 2022 |
Méthylation/déméthylation de l’ADN et expression du génome PF Cartron, R Pacaud, G Salbert Revue Francophone des Laboratoires 2015 (473), 37-48, 2015 | 4 | 2015 |
Clinical Applications of Histone Deacetylase Inhibitors R Pacaud, J Garcia, S Thomas, PN Munster Handbook of Epigenetics, 793-819, 2023 | 1 | 2023 |
Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors R Pacaud, S Thomas, S Chaudhuri, A Lazar, LA Timmerman, PN Munster Breast Cancer Research 27 (1), 8, 2025 | | 2025 |
Synthetic Lethality Beyond BRCA: A Phase I Study of Rucaparib and Irinotecan in Metastatic Solid Tumors With Homologous Recombination-Deficiency Mutations Beyond BRCA1/2 ES Tsang, MS Dhawan, R Pacaud, S Thomas, J Grabowsky, L Wilch, ... JCO Precision Oncology 8, e2300494, 2024 | | 2024 |
A phase Ib trial of alpelisib and weekly cisplatin in patients with solid tumor malignancies. ES Tsang, RR Aggarwal, MS Dhawan, R Pacaud, D Fattah, S Thomas, ... Journal of Clinical Oncology 39 (15_suppl), 3134-3134, 2021 | | 2021 |
Abstract PS8-13: Silicone implant based sustained localized drug delivery of fulvestrant to prevent breast cancer PN Munster, PK Desai, N Pawlowska, E Roche, R Pacaud, MA Daud, ... Cancer Research 81 (4_Supplement), PS8-13-PS8-13, 2021 | | 2021 |
Abstract P3-11-12: Epigenetic modulation to deepen and prolong the response to PARP inhibitors R Pacaud, M Dhawan, S Thomas, E Roche, J Garcia, N Pawlowska, ... Cancer Research 80 (4_Supplement), P3-11-12-P3-11-12, 2020 | | 2020 |
Abstract P6-21-10: Not presented R Pacaud, S Thomas, E Roche, N Pawlowska, P Munster Cancer Research 79 (4_Supplement), P6-21-10-P6-21-10, 2019 | | 2019 |
Talazoparib and decitabine: a promising combination for BRCA-mutated cancers treatment R Pacaud, S Thomas, E Roche, N Pawlowska, M Dhawan, P Munster EUROPEAN JOURNAL OF CANCER 103, E28-E28, 2018 | | 2018 |