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Francis Shue
Francis Shue
Mayo Clinic Graduate School
在 mayo.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Distinct hippocampal engrams control extinction and relapse of fear memory
AF Lacagnina, ET Brockway, CR Crovetti, F Shue, MJ McCarty, KP Sattler, ...
Nature neuroscience 22 (5), 753-761, 2019
2292019
APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids
J Zhao, Y Fu, Y Yamazaki, Y Ren, MD Davis, CC Liu, W Lu, X Wang, ...
Nature communications 11 (1), 5540, 2020
2212020
Alzheimer’s risk factors age, APOE genotype, and sex drive distinct molecular pathways
N Zhao, Y Ren, Y Yamazaki, W Qiao, F Li, LM Felton, ...
Neuron 106 (5), 727-742. e6, 2020
1792020
APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease
Z Li, F Shue, N Zhao, M Shinohara, G Bu
Molecular neurodegeneration 15 (1), 63, 2020
1662020
Dentate gyrus contributes to retrieval as well as encoding: evidence from context fear conditioning, recall, and extinction
BE Bernier, AF Lacagnina, A Ayoub, F Shue, BV Zemelman, FB Krasne, ...
Journal of Neuroscience 37 (26), 6359-6371, 2017
1592017
APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid
N Zhao, ON Attrebi, Y Ren, W Qiao, B Sonustun, YA Martens, ...
Science translational medicine 12 (529), eaay1809, 2020
1142020
Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function
CC Liu, J Zhao, Y Fu, Y Inoue, Y Ren, Y Chen, SV Doss, F Shue, ...
Nature neuroscience 25 (8), 1020-1033, 2022
892022
Dorsal and ventral hippocampal adult-born neurons contribute to context fear memory
KA Huckleberry, F Shue, T Copeland, RA Chitwood, W Yin, MR Drew
Neuropsychopharmacology 43 (12), 2487-2496, 2018
852018
APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia
CC Liu, ME Murray, X Li, N Zhao, N Wang, MG Heckman, F Shue, ...
Science translational medicine 13 (613), eabc9375, 2021
502021
Vascular ApoE4 impairs behavior by modulating gliovascular function
Y Yamazaki, CC Liu, A Yamazaki, F Shue, YA Martens, Y Chen, W Qiao, ...
Neuron 109 (3), 438-447. e6, 2021
432021
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease
Y Inoue, F Shue, G Bu, T Kanekiyo
Molecular neurodegeneration 18 (1), 46, 2023
422023
Activation of FAK/Rac1/Cdc42‐GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 …
Z Rong, B Cheng, L Zhong, X Ye, X Li, L Jia, Y Li, F Shue, N Wang, ...
The FASEB Journal 34 (8), 10984-10997, 2020
292020
Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination
N Wang, M Wang, S Jeevaratnam, C Rosenberg, TC Ikezu, F Shue, ...
Molecular neurodegeneration 17 (1), 75, 2022
252022
Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer’s disease
CC Liu, N Wang, Y Chen, Y Inoue, F Shue, Y Ren, M Wang, W Qiao, ...
Nature immunology 24 (11), 1854-1866, 2023
242023
Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids
J Zhao, W Lu, Y Ren, Y Fu, YA Martens, F Shue, MD Davis, X Wang, ...
Acta neuropathologica 142 (5), 807-825, 2021
242021
A mouse model of stress-enhanced fear learning demonstrates extinction-sensitive and extinction-resistant effects of footshock stress
AM Hassien, F Shue, BE Bernier, MR Drew
Behavioural brain research 379, 112391, 2020
242020
Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology
W Qiao, Y Chen, J Zhong, BJ Madden, CM Charlesworth, YA Martens, ...
Molecular neurodegeneration 18 (1), 8, 2023
82023
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4
H Oue, Y Yamazaki, W Qiao, C Yuanxin, Y Ren, A Kurti, F Shue, ...
JCI insight 8 (7), 2023
52023
Preparation of single cell suspensions enriched in mouse brain vascular cells for single-cell RNA sequencing
A Yamazaki, F Shue, Y Yamazaki, YA Martens, G Bu, CC Liu
STAR protocols 2 (3), 100715, 2021
32021
Upregulation of sFRP1 is more profound in female than male 5xFAD mice and positively associated with amyloid pathology
JR Macyczko, N Wang, W Lu, S Jeevaratnam, F Shue, Y Martens, CC Liu, ...
Journal of Alzheimer's Disease, 1-7, 2023
22023
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