Learning and age-related changes in genome-wide H2A. Z binding in the mouse hippocampus G Stefanelli, AB Azam, BJ Walters, MA Brimble, CP Gettens, ... Cell reports 22 (5), 1124-1131, 2018 | 90 | 2018 |
Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium Z Liu, BJ Walters, T Owen, MA Brimble, KA Steigelman, LL Zhang, ... Journal of Neuroscience 32 (31), 10530-10540, 2012 | 77 | 2012 |
KDM5A regulates a translational program that controls p53 protein expression D Hu, C Jablonowski, PH Cheng, A AlTahan, C Li, Y Wang, L Palmer, ... Iscience 9, 84-100, 2018 | 24 | 2018 |
New and improved AAVenues: current status of hemophilia B gene therapy MA Brimble, UM Reiss, AC Nathwani, AM Davidoff Expert opinion on biological therapy 16 (1), 79-92, 2016 | 24 | 2016 |
Off-target expression of cre-dependent adeno-associated viruses in wild-type C57BL/6J mice JJ Botterill, A Khlaifia, BJ Walters, MA Brimble, HE Scharfman, ... eneuro 8 (6), 2021 | 19 | 2021 |
High-Throughput Screening Reveals Alsterpaullone, 2-Cyanoethyl as a Potent p27Kip1 Transcriptional Inhibitor BJ Walters, W Lin, S Diao, M Brimble, LI Iconaru, J Dearman, A Goktug, ... PloS one 9 (3), e91173, 2014 | 18 | 2014 |
The histone chaperone Anp32e regulates memory formation, transcription, and dendritic morphology by regulating steady-state H2A. Z binding in neurons G Stefanelli, CE Makowski, MA Brimble, M Hall, A Reda, SD Creighton, ... Cell reports 36 (7), 2021 | 12 | 2021 |
Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice G Singh, G Stefanelli, K Narkaj, MA Brimble, SD Creighton, TAB McLean, ... Communications Biology 5 (1), 482, 2022 | 9 | 2022 |
Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps MA Brimble, PH Cheng, SM Winston, IL Reeves, A Souquette, Y Spence, ... Molecular Therapy-Methods & Clinical Development 24, 280-291, 2022 | 8 | 2022 |
547. AAV preparations contain contamination from DNA sequences in production plasmids directly outside of the ITRs MA Brimble, J Zhou, C Morton, M Meagher, AC Nathwani, JT Gray, ... Molecular Therapy 24, S218-S219, 2016 | 6 | 2016 |
Stowaways in the cargo: Contaminating nucleic acids in rAAV preparations for gene therapy. MA Brimble, SM Winston, AM Davidoff Molecular Therapy, 2023 | 5 | 2023 |
Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues G Casey, C Askew, MA Brimble, RJ Samulski, AM Davidoff, C Li, ... Plos one 15 (11), e0242599, 2020 | 5 | 2020 |
KDM5A Regulates a Translational Program that Controls p53 Protein Expression. iScience, 9, 84–100 D Hu, C Jablonowski, PH Cheng, A AlTahan, C Li, Y Wang, L Palmer, ... DOI: https://doi. org/10.1016/j. isci 12, 2018 | 5 | 2018 |
Spring Forward: ESGCT Trains the Next Generation of Gene and Cell Therapists. VMA Woods, MA Brimble Human Gene Therapy 29 (10), 1074-1075, 2018 | 2 | 2018 |
Author Correction: Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice G Singh, G Stefanelli, K Narkaj, MA Brimble, SD Creighton, TAB McLean, ... Communications Biology 5, 2022 | 1 | 2022 |
Threat-dependent scaling of prelimbic dynamics to enhance fear representation JP Casanova, C Pouget, N Treiber, I Agarwal, MA Brimble, G Vetere Neuron, 2024 | | 2024 |
The role of the m6A/m demethylase FTO in memory is both task and sex-dependent in mice AM Leonetti, IR Galluzzo, TAD McLean, G Stefanelli, F Ramnaraign, ... Neurobiology of Learning and Memory 210, 107903, 2024 | | 2024 |
Pre-Existing Immunity to a Nucleic Acid Contaminant-Derived Antigen Mediates Transaminitis and Resultant Diminished Transgene Expression in a Mouse Model of Hepatic Recombinant … MA Brimble, CL Morton, SM Winston, IL Reeves, Y Spence, PH Cheng, ... Human Gene Therapy, 2024 | | 2024 |
Role of the histone variant H2A. Z. 1 in memory, transcription, and alternative splicing is mediated by lysine modification A Reda, LA Hategan, TAB McLean, SD Creighton, JQ Luo, SES Chen, ... Neuropsychopharmacology, 1-11, 2024 | | 2024 |
Recombinant P5 Promoter for Use in Reducing DNA Contamination of AAV Preparations M BRIMBLE, A Davidoff, PH CHENG, C Morton US Patent App. 17/927,038, 2023 | | 2023 |