Topical treatments for skin cancer JK Cullen, JL Simmons, PG Parsons, GM Boyle Advanced drug delivery reviews 153, 54-64, 2020 | 139 | 2020 |
R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias AJ Yeo, OJ Becherel, JE Luff, JK Cullen, T Wongsurawat, ... PLoS One 9 (3), e90219, 2014 | 70 | 2014 |
Failed gene conversion leads to extensive end processing and chromosomal rearrangements in fission yeast H Tinline‐Purvis, AP Savory, JK Cullen, A Davé, J Moss, WL Bridge, ... The EMBO journal 28 (21), 3400-3412, 2009 | 56 | 2009 |
Inactivation of the Akt survival pathway during photoreceptor apoptosis in the retinal degeneration mouse C Jomary, J Cullen, SE Jones Investigative ophthalmology & visual science 47 (4), 1620-1629, 2006 | 56 | 2006 |
Break-induced loss of heterozygosity in fission yeast: dual roles for homologous recombination in promoting translocations and preventing de novo telomere addition JK Cullen, SP Hussey, C Walker, J Prudden, BY Wee, A Davé, JS Findlay, ... Molecular and cellular biology 27 (21), 7745-7757, 2007 | 39 | 2007 |
Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes JK Cullen, GM Boyle, PY Yap, S Elmlinger, JL Simmons, N Broit, J Johns, ... Scientific Reports 11 (1), 207, 2021 | 29 | 2021 |
AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation JK Cullen, N Abdul Murad, A Yeo, M McKenzie, M Ward, KL Chong, ... PLoS One 11 (2), e0148213, 2016 | 26 | 2016 |
Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate CME Barnett, N Broit, PY Yap, JK Cullen, PG Parsons, BJ Panizza, ... Investigational New Drugs 37, 1-8, 2019 | 21 | 2019 |
Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore YC Lim, KS Ensbey, C Offenhäuser, RCJ D’souza, JK Cullen, BW Stringer, ... Neuro-oncology 22 (2), 216-228, 2020 | 17 | 2020 |
Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds LC Powell, JK Cullen, GM Boyle, T De Ridder, PY Yap, W Xue, CJ Pierce, ... Science Translational Medicine 14 (662), eabn3758, 2022 | 16 | 2022 |
Potent Antibacterial Prenylated Acetophenones from the Australian Endemic Plant Acronychia crassipetala TD Tran, MA Olsson, DJ McMillan, JK Cullen, PG Parsons, PW Reddell, ... Antibiotics 9 (8), 487, 2020 | 16 | 2020 |
Pro-fluorescent mitochondria-targeted real-time responsive redox probes synthesised from carboxy isoindoline nitroxides: Sensitive probes of mitochondrial redox status in cells KL Chong, BA Chalmers, JK Cullen, A Kaur, JL Kolanowski, BJ Morrow, ... Free Radical Biology and Medicine 128, 97-110, 2018 | 15 | 2018 |
Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks A Davé, CC Pai, SC Durley, L Hulme, S Sarkar, BY Wee, J Prudden, ... Nucleic acids research 48 (3), 1271-1284, 2020 | 12 | 2020 |
Ternstroenols A–E: Undescribed pentacyclic triterpenoids from the Australian rainforest plant Ternstroemia cherryi A Singh, JK Cullen, ZC Bruce, P Reddell, G Münch, R Raju Phytochemistry 176, 112426, 2020 | 8 | 2020 |
Antibacterial 5α-Spirostane Saponins from the Fruit of Cordyline manners-suttoniae TD Tran, MA Olsson, MA Choudhury, DJ McMillan, JK Cullen, PG Parsons, ... Journal of natural products 82 (10), 2809-2817, 2019 | 7 | 2019 |
Mitochondrial dysfunction in a novel form of autosomal recessive ataxia NAA Murad, JK Cullen, M McKenzie, MT Ryan, D Thorburn, N Gueven, ... Mitochondrion 13 (3), 235-245, 2013 | 5 | 2013 |
Eupomatenes A–E: Neolignans isolated from the leaves of Australian rainforest plant Eupomatia laurina R Raju, JK Cullen, ZC Bruce, P Reddell, G Münch Fitoterapia 153, 104972, 2021 | 4 | 2021 |
Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (Fontainea picrosperma) G Chianese, HIM Amin, C Maioli, P Reddell, P Parsons, J Cullen, J Johns, ... Journal of Natural Products 85 (8), 1959-1966, 2022 | 3 | 2022 |
Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade JK Cullen, PY Yap, B Ferguson, ZC Bruce, M Koyama, H Handoko, ... Journal for Immunotherapy of Cancer 12 (4), 2024 | 2 | 2024 |
Insignoic acids A–E, unusual α, β-unsaturated keto fatty acids isolated from the exocarp of Australian rainforest tree Endiandra insignis (Lauraceae) R Raju, P Kumar, P Reddell, J Cullen, D Harman, AT Maccarone, C Kelso, ... Fitoterapia 173, 105815, 2024 | 1 | 2024 |