Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis K Shimada, TR Crother, J Karlin, J Dagvadorj, N Chiba, S Chen, ... Immunity 36 (3), 401-414, 2012 | 2097 | 2012 |
Hexokinase is an innate immune receptor for the detection of bacterial peptidoglycan AJ Wolf, CN Reyes, W Liang, C Becker, K Shimada, ML Wheeler, HC Cho, ... Cell 166 (3), 624-636, 2016 | 509 | 2016 |
Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease Y Lee, DJ Schulte, K Shimada, S Chen, TR Crother, N Chiba, ... Circulation 125 (12), 1542-1550, 2012 | 222 | 2012 |
Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer EL Lowe, TR Crother, S Rabizadeh, B Hu, H Wang, S Chen, K Shimada, ... PloS one 5 (9), e13027, 2010 | 187 | 2010 |
The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection K Shimada, S Chen, PW Dempsey, R Sorrentino, R Alsabeh, ... PLoS pathogens 5 (4), e1000379, 2009 | 175 | 2009 |
Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis G Tumurkhuu, K Shimada, J Dagvadorj, TR Crother, W Zhang, ... Circulation research 119 (6), e76-e90, 2016 | 165 | 2016 |
Pulmonary collectins enhance phagocytosis of Mycobacterium avium through increased activity of mannose receptor K Kudo, H Sano, H Takahashi, K Kuronuma, S Yokota, N Fujii, K Shimada, ... The Journal of Immunology 172 (12), 7592-7602, 2004 | 151 | 2004 |
IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice S Chen, K Shimada, W Zhang, G Huang, TR Crother, M Arditi The Journal of Immunology 185 (9), 5619-5627, 2010 | 146 | 2010 |
Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection S Divanovic, NM Sawtell, A Trompette, JI Warning, A Dias, AM Cooper, ... Journal of Infectious Diseases 205 (1), 152-161, 2012 | 134 | 2012 |
Lipopolysaccharide induces alveolar macrophage necrosis via CD14 and the P2X7 receptor leading to interleukin-1α release J Dagvadorj, K Shimada, S Chen, HD Jones, G Tumurkhuu, W Zhang, ... Immunity 42 (4), 640-653, 2015 | 129 | 2015 |
The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury HD Jones, TR Crother, RA Gonzalez-Villalobos, M Jupelli, S Chen, ... American journal of respiratory cell and molecular biology 50 (2), 270-280, 2014 | 129 | 2014 |
TLR/MyD88 and liver X receptor α signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis Y Naiki, R Sorrentino, MH Wong, KS Michelsen, K Shimada, S Chen, ... The Journal of immunology 181 (10), 7176-7185, 2008 | 126 | 2008 |
Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection K Shimada, TR Crother, J Karlin, S Chen, N Chiba, VK Ramanujan, ... PloS one 6 (6), e21477, 2011 | 123 | 2011 |
Intestinal permeability and IgA provoke immune vasculitis linked to cardiovascular inflammation MN Rivas, D Wakita, MK Franklin, TT Carvalho, A Abolhesn, AC Gomez, ... Immunity 51 (3), 508-521. e6, 2019 | 120 | 2019 |
C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice P Kyme, NH Thoennissen, CW Tseng, GB Thoennissen, AJ Wolf, ... The Journal of clinical investigation 122 (9), 3316-3329, 2012 | 114 | 2012 |
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and-independent signaling and is reciprocally modulated by liver X receptor activation S Chen, R Sorrentino, K Shimada, Y Bulut, TM Doherty, TR Crother, ... The Journal of Immunology 181 (10), 7186-7193, 2008 | 106 | 2008 |
Role of interleukin-1 signaling in a mouse model of kawasaki disease–associated abdominal aortic aneurysm D Wakita, Y Kurashima, TR Crother, M Noval Rivas, Y Lee, S Chen, ... Arteriosclerosis, thrombosis, and vascular biology 36 (5), 886-897, 2016 | 103 | 2016 |
IL-1 signaling is critically required in stromal cells in Kawasaki disease vasculitis mouse model: role of both IL-1α and IL-1β Y Lee, D Wakita, J Dagvadorj, K Shimada, S Chen, G Huang, ... Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2605-2616, 2015 | 101 | 2015 |
Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria AJ Wolf, A Arruda, CN Reyes, AT Kaplan, T Shimada, K Shimada, M Arditi, ... The Journal of Immunology 187 (11), 6002-6010, 2011 | 100 | 2011 |
Involvement of innate and adaptive immunity in a murine model of coronary arteritis mimicking Kawasaki disease DJ Schulte, A Yilmaz, K Shimada, MC Fishbein, EL Lowe, S Chen, ... The Journal of Immunology 183 (8), 5311-5318, 2009 | 97 | 2009 |