Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 189 | 2017 |
Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis GE Tyzack, R Luisier, DM Taha, J Neeves, M Modic, JS Mitchell, I Meyer, ... Brain 142 (9), 2572-2580, 2019 | 169 | 2019 |
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS R Luisier, GE Tyzack, CE Hall, JS Mitchell, H Devine, DM Taha, B Malik, ... Nature communications 9 (1), 2010, 2018 | 149 | 2018 |
c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells L Gabryšová, M Alvarez-Martinez, R Luisier, LS Cox, J Sodenkamp, ... Nature immunology 19 (5), 497-507, 2018 | 146 | 2018 |
Identification of Dlk1-Dio3 Imprinted Gene Cluster Noncoding RNAs as Novel Candidate Biomarkers for Liver Tumor Promotion H Lempiäinen, P Couttet, F Bolognani, A Mueller, V Dubost, R Luisier, ... Toxicological sciences 131 (2), 375-386, 2013 | 79 | 2013 |
Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors R Luisier, H Lempiäinen, N Scherbichler, A Braeuning, M Geissler, ... Toxicological Sciences 139 (2), 501-511, 2014 | 73 | 2014 |
NOA 63 as a UV-curable material for fabrication of microfluidic channels with native hydrophilicity EP Dupont, R Luisier, MAM Gijs Microelectronic engineering 87 (5-8), 1253-1255, 2010 | 72 | 2010 |
Cytoplasmic cleavage of IMPA1 3′ UTR is necessary for maintaining axon integrity C Andreassi, R Luisier, H Crerar, M Darsinou, S Blokzijl-Franke, T Lenn, ... Cell Reports 34 (8), 2021 | 45* | 2021 |
Ha‐ras and β‐catenin oncoproteins orchestrate metabolic programs in mouse liver tumors EB Unterberger, J Eichner, C Wrzodek, H Lempiäinen, R Luisier, ... International journal of cancer 135 (7), 1574-1585, 2014 | 34 | 2014 |
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology OJ Ziff, J Neeves, J Mitchell, G Tyzack, C Martinez-Ruiz, R Luisier, ... Nature Communications 14 (1), 2176, 2023 | 25* | 2023 |
Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion R Luisier, EB Unterberger, JI Goodman, M Schwarz, J Moggs, ... Nucleic acids research 42 (7), 4180-4195, 2014 | 21 | 2014 |
Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis GE Tyzack, J Neeves, H Crerar, P Klein, O Ziff, DM Taha, R Luisier, ... Brain 144 (7), 1985-1993, 2021 | 20* | 2021 |
Automated and unbiased discrimination of ALS from control tissue at single cell resolution C Hagemann, GE Tyzack, DM Taha, H Devine, L Greensmith, ... Brain Pathology 31 (4), e12937, 2021 | 10 | 2021 |
Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis MP Howe, H Crerar, J Neeves, J Harley, GE Tyzack, P Klein, A Ramos, ... Genome Research 32 (10), 1808-1825, 2022 | 9* | 2022 |
Mammary epithelial morphogenesis in 3D combinatorial microenvironments R Luisier, M Girgin, MP Lutolf, A Ranga Scientific Reports 10 (1), 21635, 2020 | 7 | 2020 |
Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS GE Tyzack, G Manferrari, J Newcombe, NM Luscombe, R Luisier, ... Brain 143 (8), e66-e66, 2020 | 7 | 2020 |
Image‐based deep learning reveals the responses of human motor neurons to stress and VCP‐related ALS C Verzat, J Harley, R Patani, R Luisier Neuropathology and Applied Neurobiology 48 (2), e12770, 2022 | 6 | 2022 |
Epigenomics–impact for drug safety sciences H Lempiäinen, R Luisier, A Müller, P Marc, D Heard, F Bolognani, ... Toxicology and Epigenetics, 365-385, 2012 | 4 | 2012 |
The predicted RNA-binding protein regulome of axonal mRNAs R Luisier, C Andreassi, L Fournier, A Riccio Genome Research 33 (9), 1497-1512, 2023 | 2* | 2023 |
Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells LS Cox, M Alvarez-Martinez, X Wu, L Gabryšová, R Luisier, J Briscoe, ... Wellcome Open Research 8, 2023 | 2 | 2023 |