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Cheng Ji
Cheng Ji
Principle research scientist, Abbvie Inc.
在 abbvie.com 的电子邮件经过验证
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引用次数
引用次数
年份
Iron Transport-Mediated Drug Delivery: Practical Syntheses and In Vitro Antibacterial Studies of Tris-Catecholate Siderophore–Aminopenicillin Conjugates Reveals Selectively …
C Ji, PA Miller, MJ Miller
Journal of the American Chemical Society 134 (24), 9898-9901, 2012
1852012
Exploiting bacterial iron acquisition: siderophore conjugates
C Ji, RE Juárez-Hernández, MJ Miller
Future medicinal chemistry 4 (3), 297-313, 2012
1702012
Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers
C Ji, MJ Miller
Bioorganic & medicinal chemistry 20 (12), 3828-3836, 2012
1022012
Structural basis for adenylation and thioester bond formation in the ubiquitin E1
ZS Hann, C Ji, SK Olsen, X Lu, MC Lux, DS Tan, CD Lima
Proceedings of the National Academy of Sciences 116 (31), 15475-15484, 2019
652019
Siderophore–fluoroquinolone conjugates containing potential reduction-triggered linkers for drug release: synthesis and antibacterial activity
C Ji, MJ Miller
BioMetals 28, 541-551, 2015
612015
Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa
C Ji, I Sharma, D Pratihar, LL Hudson, D Maura, T Guney, LG Rahme, ...
ACS Chemical Biology 11 (11), 3061-3067, 2016
592016
Syntheses and Antibacterial Activity of N-Acylated Ciprofloxacin Derivatives Based on the Trimethyl Lock
C Ji, PA Miller, MJ Miller
ACS medicinal chemistry letters 6 (6), 707-710, 2015
492015
A Novel Dinuclear Ruthenium (I)/Ruthenium (III) Half-Sandwich Complex Containing Two Chelating 1, 2-Dicarba-closo-dodecaborane-1, 2-dithiolate Ligands and Its Reactivity with …
DH Wu, C Ji, YZ Li, H Yan
Organometallics 26 (7), 1560-1562, 2007
342007
Cyclopropanation of nitroso Diels–Alder cycloadducts and application to the synthesis of a 2′, 3′-methano carbocyclic nucleoside
C Ji, MJ Miller
Tetrahedron letters 51 (29), 3789-3791, 2010
212010
Reactivity of the 16e (p-cymene) Ru half-sandwich complex containing a chelating 1, 2-dicarba-closo-dodecaborane-1, 2-dithiolate ligand towards diynes
ZW Xu, L Han, C Ji, R Zhang, XJ Shen, H Yan
Dalton Transactions 40 (26), 6992-6997, 2011
172011
Kinetic analyses of the siderophore biosynthesis inhibitor salicyl-AMS and analogues as MbtA inhibitors and antimycobacterial agents
GV Bythrow, P Mohandas, T Guney, LC Standke, GA Germain, X Lu, C Ji, ...
Biochemistry 58 (6), 833-847, 2018
142018
Syntheses and biological studies of novel spiropiperazinyl oxazolidinone antibacterial agents using a spirocyclic diene derived acylnitroso Diels− Alder reaction
C Ji, W Lin, GC Moraski, JA Thanassi, MJ Pucci, SG Franzblau, ...
Bioorganic & medicinal chemistry 20 (11), 3422-3428, 2012
132012
ABBV-400: An ADC delivering a novel topoisomerase 1 inhibitor to c-Met-positive solid tumors
RM Reilly, C Ji, RP Matuszak, MG Anderson, L Tucker, N Klunder, ...
Cancer Research 83 (7_Supplement), 6311-6311, 2023
62023
Structural basis for transthiolation intermediates in the ubiquitin pathway
T Kochańczyk, ZS Hann, MC Lux, AMV Delos Reyes, C Ji, DS Tan, ...
Nature 633 (8028), 216-223, 2024
42024
Enabling, Decagram-Scale Synthesis of Macrocyclic MCL-1 Inhibitor ABBV-467
PB Brady, BK Sorensen, RM Risi, ML Curtin, RA Mantei, AS Florjancic, ...
The Journal of Organic Chemistry 88 (22), 15562-15568, 2023
32023
Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes
N Kinarivala, LC Standke, T Guney, C Ji, N Noguchi, Y Asano, DS Tan
Methods in enzymology 638, 69-87, 2020
32020
Design and Semisynthesis of Biselectrophile-Functionalized Ubiquitin Probes To Investigate Transthioesterification Reactions
AMV Delos Reyes, MC Lux, ZS Hann, C Ji, T Kochańczyk, M DiBello, ...
Organic Letters, 2024
22024
Macrocyclic compounds as Mcl-1 inhibitors and their preparation and use
P Brady, W Braje, Y Dai, G Doherty, J Gong, K Jantos, C Ji, A Judd, ...
WO2019035899, 2019
22019
Preparation of macrocyclic Mcl-1 inhibitors for the treatment of cancer
W Braje, G Doherty, K Jantos, C Ji, A Judd, A Kunzer, A Mastracchio, ...
WO2019035911, 2019
22019
Obacunone
X Zhou, C Ji, J Fu, YG Li, T Chen
Acta Crystallographica Section E: Structure Reports Online 62 (12), o5544-o5546, 2006
22006
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