Disrupting proton dynamics and energy metabolism for cancer therapy SK Parks, J Chiche, J Pouysségur Nature Reviews Cancer 13 (9), 611-623, 2013 | 661 | 2013 |
pH control mechanisms of tumor survival and growth SK Parks, J Chiche, J Pouyssegur Journal of cellular physiology 226 (2), 299-308, 2011 | 429 | 2011 |
MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines S Grosso, J Doyen, SK Parks, T Bertero, A Paye, B Cardinaud, P Gounon, ... Cell death & disease 4 (3), e544-e544, 2013 | 248 | 2013 |
Genetic ablation of the cystine transporter xCT in PDAC cells inhibits mTORC1, growth, survival, and tumor formation via nutrient and oxidative stresses B Daher, SK Parks, J Durivault, Y Cormerais, H Baidarjad, E Tambutte, ... Cancer research 79 (15), 3877-3890, 2019 | 171 | 2019 |
Genetic disruption of the multifunctional CD98/LAT1 complex demonstrates the key role of essential amino acid transport in the control of mTORC1 and tumor growth Y Cormerais, S Giuliano, R LeFloch, B Front, J Durivault, E Tambutté, ... Cancer research 76 (15), 4481-4492, 2016 | 163 | 2016 |
The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5) Y Cormerais, PA Massard, M Vucetic, S Giuliano, E Tambutté, J Durivault, ... Journal of Biological Chemistry 293 (8), 2877-2887, 2018 | 158 | 2018 |
Hypoxia and cellular metabolism in tumour pathophysiology SK Parks, Y Cormerais, J Pouysségur The Journal of physiology 595 (8), 2439-2450, 2017 | 134 | 2017 |
Theoretical considerations underlying Na+ uptake mechanisms in freshwater fishes SK Parks, M Tresguerres, GG Goss Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2008 | 130 | 2008 |
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium EO Pettersen, P Ebbesen, RG Gieling, KJ Williams, L Dubois, P Lambin, ... Journal of enzyme inhibition and medicinal chemistry 30 (5), 689-721, 2015 | 128 | 2015 |
Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome J Doyen, C Trastour, F Ettore, I Peyrottes, N Toussant, J Gal, K Ilc, D Roux, ... Biochemical and biophysical research communications 451 (1), 54-61, 2014 | 118 | 2014 |
Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis M Tresguerres, SK Parks, E Salazar, LR Levin, GG Goss, J Buck Proceedings of the National Academy of Sciences 107 (1), 442-447, 2010 | 112 | 2010 |
The central role of amino acids in cancer redox homeostasis: vulnerability points of the cancer redox code M Vučetić, Y Cormerais, SK Parks, J Pouysségur Frontiers in oncology 7, 319, 2017 | 110 | 2017 |
Signal transduction in multifactorial neuroendocrine control of gonadotropin secretion and synthesis in teleosts—studies on the goldfish model JP Chang, JD Johnson, GR Sawisky, CL Grey, G Mitchell, M Booth, ... General and comparative endocrinology 161 (1), 42-52, 2009 | 106 | 2009 |
The Na+/HCO3− Co‐Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells SK Parks, J Pouyssegur Journal of cellular physiology 230 (8), 1954-1963, 2015 | 98 | 2015 |
Microtubule-dependent relocation of branchial V-H+-ATPase to the basolateral membrane in the Pacific spiny dogfish (Squalus acanthias): a role in base secretion M Tresguerres, SK Parks, F Katoh, GG Goss Journal of experimental biology 209 (4), 599-609, 2006 | 96 | 2006 |
Circulating tumor cells in prostate cancer: a potential surrogate marker of survival J Doyen, C Alix-Panabieres, P Hofman, SK Parks, E Chamorey, H Naman, ... Critical reviews in oncology/hematology 81 (3), 241-256, 2012 | 93 | 2012 |
Interactions between Na+ channels and Na+-HCO3− cotransporters in the freshwater fish gill MR cell: a model for transepithelial Na+ uptake SK Parks, M Tresguerres, GG Goss American Journal of Physiology-Cell Physiology 292 (2), C935-C944, 2007 | 86 | 2007 |
Chloride uptake and base secretion in freshwater fish: a transepithelial ion-transport metabolon? M Tresguerres, F Katoh, E Orr, SK Parks, GG Goss Physiological and Biochemical Zoology 79 (6), 981-996, 2006 | 86 | 2006 |
V-H+-ATPase translocation during blood alkalosis in dogfish gills: interaction with carbonic anhydrase and involvement in the postfeeding alkaline tide M Tresguerres, SK Parks, CM Wood, GG Goss American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007 | 82 | 2007 |
Lactate and acidity in the cancer microenvironment SK Parks, W Mueller-Klieser, J Pouysségur Annual Review of Cancer Biology 4, 141-158, 2020 | 80 | 2020 |