Regulation of monoubiquitinated PCNA by DUB autocleavage TT Huang, SMB Nijman, KD Mirchandani, PJ Galardy, MA Cohn, W Haas, ... Nature cell biology 8 (4), 341-347, 2006 | 664 | 2006 |
Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib CR Berkers, M Verdoes, E Lichtman, E Fiebiger, BM Kessler, ... Nature methods 2 (5), 357-362, 2005 | 323 | 2005 |
DUBs and cancer: the role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors S Hussain, Y Zhang, P Galardy Cell cycle 8 (11), 1688-1697, 2009 | 298 | 2009 |
Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells H Ovaa, BM Kessler, U Rolén, PJ Galardy, HL Ploegh, MG Masucci Proceedings of the National Academy of Sciences 101 (8), 2253-2258, 2004 | 230 | 2004 |
Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate S Misaghi, PJ Galardy, WJN Meester, H Ovaa, HL Ploegh, R Gaudet Journal of Biological Chemistry 280 (2), 1512-1520, 2005 | 229 | 2005 |
Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy H Ovaa, PF Van Swieten, BM Kessler, MA Leeuwenburgh, E Fiebiger, ... Angewandte Chemie (International ed. in English) 42 (31), 3626-3629, 2003 | 219 | 2003 |
Effects of PS-341 on the activity and composition of proteasomes in multiple myeloma cells M Altun, PJ Galardy, R Shringarpure, T Hideshima, R LeBlanc, ... Cancer research 65 (17), 7896-7901, 2005 | 180 | 2005 |
USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis Y Zhang, O Foreman, DA Wigle, F Kosari, G Vasmatzis, JL Salisbury, ... The Journal of clinical investigation 122 (12), 4362-4374, 2012 | 162 | 2012 |
Rituximab with chemotherapy in children and adolescents with central nervous system and/or bone marrow‐positive B urkitt lymphoma/leukaemia: a Children's Oncology Group Report S Goldman, L Smith, P Galardy, SL Perkins, JK Frazer, W Sanger, ... British journal of haematology 167 (3), 394-401, 2014 | 139 | 2014 |
Mitotic regulation of the anaphase-promoting complex DJ Baker, MM Dawlaty, P Galardy, JM Van Deursen Cellular and molecular life sciences 64, 589-600, 2007 | 139 | 2007 |
The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling S Hussain, O Foreman, SL Perkins, TE Witzig, RR Miles, J Van Deursen, ... Leukemia 24 (9), 1641-1655, 2010 | 136 | 2010 |
Gene expression analysis of B‐lymphoma cells resistant and sensitive to bortezomib R Shringarpure, L Catley, D Bhole, R Burger, K Podar, YT Tai, B Kessler, ... British journal of haematology 134 (2), 145-156, 2006 | 132 | 2006 |
Screen for ISG15-crossreactive deubiquitinases A Catic, E Fiebiger, GA Korbel, D Blom, PJ Galardy, HL Ploegh PloS one 2 (7), e679, 2007 | 123 | 2007 |
Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases J Hemelaar, PJ Galardy, A Borodovsky, BM Kessler, HL Ploegh, H Ovaa Journal of proteome research 3 (2), 268-276, 2004 | 93 | 2004 |
Presentation of endogenous and exogenous antigens is not affected by inactivation of E1 ubiquitin-activating enzyme in temperature-sensitive cell lines. JH Cox, P Galardy, JR Bennink, JW Yewdell Journal of immunology (Baltimore, Md.: 1950) 154 (2), 511-519, 1995 | 89 | 1995 |
Children's Oncology Group Trial AALL1231: a phase III clinical trial testing bortezomib in newly diagnosed T-cell acute lymphoblastic leukemia and lymphoma DT Teachey, M Devidas, BL Wood, Z Chen, RJ Hayashi, ML Hermiston, ... Journal of Clinical Oncology 40 (19), 2106-2118, 2022 | 88 | 2022 |
Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor S Hussain, AL Feldman, C Das, SC Ziesmer, SM Ansell, PJ Galardy Molecular and cellular biology 33 (6), 1188-1197, 2013 | 87 | 2013 |
Rasburicase in the prevention of laboratory/clinical tumour lysis syndrome in children with advanced mature B‐NHL: a C hildren's O ncology G roup R eport PJ Galardy, J Hochberg, SL Perkins, L Harrison, S Goldman, MS Cairo British journal of haematology 163 (3), 365-372, 2013 | 69 | 2013 |
Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia Y Zhang, J van Deursen, PJ Galardy PLoS One 6 (8), e23389, 2011 | 68 | 2011 |
Rare pediatric non‐Hodgkin lymphomas: a report from Children's Oncology Group study ANHL 04B1 C O'Suoji, JJG Welch, SL Perkins, LM Smith, S Weitzman, SJ Simko, ... Pediatric Blood & Cancer 63 (5), 794-800, 2016 | 59 | 2016 |