Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl MJ Franklin, DE Nivens, JT Weadge, PL Howell Frontiers in microbiology 2, 167, 2011 | 678 | 2011 |
The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix KM Colvin, Y Irie, CS Tart, R Urbano, JC Whitney, C Ryder, PL Howell, ... Environmental microbiology 14 (8), 1913-1928, 2012 | 670 | 2012 |
Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix LK Jennings, KM Storek, HE Ledvina, C Coulon, LS Marmont, ... Proceedings of the National Academy of Sciences 112 (36), 11353-11358, 2015 | 647 | 2015 |
Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange LR Hmelo, BR Borlee, H Almblad, ME Love, TE Randall, BS Tseng, C Lin, ... Nature protocols 10 (11), 1820-1841, 2015 | 465 | 2015 |
The phage λ major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system LG Pell, V Kanelis, LW Donaldson, P Lynne Howell, AR Davidson Proceedings of the National Academy of Sciences 106 (11), 4160-4165, 2009 | 324 | 2009 |
Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms P Baker, PJ Hill, BD Snarr, N Alnabelseya, MJ Pestrak, MJ Lee, ... Science advances 2 (5), e1501632, 2016 | 298 | 2016 |
Synthase-dependent exopolysaccharide secretion in Gram-negative bacteria JC Whitney, PL Howell Trends in microbiology 21 (2), 63-72, 2013 | 277 | 2013 |
Structure and function of S-adenosylhomocysteine hydrolase MA Turner, X Yang, D Yin, K Kuczera, RT Borchardt, PL Howell Cell biochemistry and biophysics 33, 101-125, 2000 | 225 | 2000 |
Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength MA Turner, CS Yuan, RT Borchardt, MS Hershfield, GD Smith, PL Howell Nature Structural Biology 5 (5), 369-376, 1998 | 208 | 1998 |
Femtomolar transition state analogue inhibitors of 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli V Singh, GB Evans, DH Lenz, JM Mason, K Clinch, S Mee, GF Painter, ... Journal of Biological Chemistry 280 (18), 18265-18273, 2005 | 189 | 2005 |
The 2.1. ANG. resolution structure of iron superoxide dismutase from Pseudomonas ovalis BL Stoddard, PL Howell, D Ringe, GA Petsko Biochemistry 29 (38), 8885-8893, 1990 | 188 | 1990 |
Structural basis for catalysis and inhibition ofn-glycan processing class I α1, 2-mannosidases F Vallée, K Karaveg, A Herscovics, KW Moremen, PL Howell Journal of Biological Chemistry 275 (52), 41287-41298, 2000 | 183 | 2000 |
Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-. ANG. resolution: identification of the active site and possible … DJ Neidhart, PL Howell, GA Petsko, VM Powers, R Li, GL Kenyon, ... Biochemistry 30 (38), 9264-9273, 1991 | 171 | 1991 |
PilM/N/O/P proteins form an inner membrane complex that affects the stability of the Pseudomonas aeruginosa type IV pilus secretin M Ayers, LM Sampaleanu, S Tammam, J Koo, H Harvey, PL Howell, ... Journal of molecular biology 394 (1), 128-142, 2009 | 160 | 2009 |
Architecture of the type II secretion and type IV pilus machineries M Ayers, PL Howell, LL Burrows Future microbiology 5 (8), 1203-1218, 2010 | 159 | 2010 |
Structure of the cytoplasmic region of PelD, a degenerate diguanylate cyclase receptor that regulates exopolysaccharide production in Pseudomonas aeruginosa JC Whitney, KM Colvin, LS Marmont, H Robinson, MR Parsek, PL Howell Journal of Biological Chemistry 287 (28), 23582-23593, 2012 | 158 | 2012 |
Pseudomonas aeruginosa Alginate Overproduction Promotes Coexistence with Staphylococcus aureus in a Model of Cystic Fibrosis Respiratory Infection DH Limoli, GB Whitfield, T Kitao, ML Ivey, MR Davis Jr, N Grahl, ... MBio 8 (2), 10.1128/mbio. 00186-17, 2017 | 157 | 2017 |
AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin CL Keiski, M Harwich, S Jain, AM Neculai, P Yip, H Robinson, JC Whitney, ... Structure 18 (2), 265-273, 2010 | 154 | 2010 |
Enzymatic modifications of exopolysaccharides enhance bacterial persistence GB Whitfield, LS Marmont, PL Howell Frontiers in microbiology 6, 471, 2015 | 144 | 2015 |
PelA deacetylase activity is required for Pel polysaccharide synthesis in Pseudomonas aeruginosa KM Colvin, N Alnabelseya, P Baker, JC Whitney, PL Howell, MR Parsek Journal of bacteriology 195 (10), 2329-2339, 2013 | 143 | 2013 |