Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 876 | 2015 |
A 1-deoxy-d-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-d-erythritol 4-phosphate in an alternative nonmevalonate pathway for … S Takahashi, T Kuzuyama, H Watanabe, H Seto Proceedings of the National Academy of Sciences 95 (17), 9879-9884, 1998 | 664 | 1998 |
Fosmidomycin, a specific inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis T Kuzuyama, T Shimizu, S Takahashi, H Seto Tetrahedron letters 39 (43), 7913-7916, 1998 | 535 | 1998 |
Terpene synthases are widely distributed in bacteria Y Yamada, T Kuzuyama, M Komatsu, K Shin-Ya, S Omura, DE Cane, ... Proceedings of the National Academy of Sciences 112 (3), 857-862, 2015 | 496 | 2015 |
Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units T Kuzuyama Bioscience, biotechnology, and biochemistry 66 (8), 1619-1627, 2002 | 406 | 2002 |
Diversity of the biosynthesis of the isoprene units T Kuzuyama, H Seto Natural product reports 20 (2), 171-183, 2003 | 364 | 2003 |
Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products T Kuzuyama, JP Noel, SB Richard Nature 435 (7044), 983-987, 2005 | 344 | 2005 |
Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins inArabidopsis H Kasahara, A Hanada, T Kuzuyama, M Takagi, Y Kamiya, S Yamaguchi Journal of Biological Chemistry 277 (47), 45188-45194, 2002 | 332 | 2002 |
Analysis of the Expression of CLA1, a Gene That Encodes the 1-Deoxyxylulose 5-Phosphate Synthase of the 2-C-Methyl-d-Erythritol-4-Phosphate Pathway in … JM Estévez, A Cantero, C Romero, H Kawaide, LF Jiménez, T Kuzuyama, ... Plant physiology 124 (1), 95-104, 2000 | 306 | 2000 |
Bioactive natural products with carbon–phosphorus bonds and their biosynthesis H Seto, T Kuzuyama Natural product reports 16 (5), 589-596, 1999 | 301 | 1999 |
An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190 K Kaneda, T Kuzuyama, M Takagi, Y Hayakawa, H Seto Proceedings of the National Academy of Sciences 98 (3), 932-937, 2001 | 239 | 2001 |
Direct formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose 5-phosphate by 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a new enzyme in the non … T Kuzuyama, S Takahashi, H Watanabe, H Seto Tetrahedron Letters 39 (25), 4509-4512, 1998 | 223 | 1998 |
Cloning and Characterization of 1-Deoxy-d-Xylulose 5-Phosphate Synthase fromStreptomyces sp. Strain CL190, Which Uses both the Mevalonate and … T Kuzuyama, M Takagi, S Takahashi, H Seto Journal of Bacteriology 182 (4), 891-897, 2000 | 188 | 2000 |
The ABBA family of aromatic prenyltransferases: broadening natural product diversity M Tello, T Kuzuyama, L Heide, JP Noel, SB Richard Cellular and molecular life sciences: CMLS 65 (10), 1459, 2008 | 169 | 2008 |
Formation of 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol from 2-C-methyl-D-erythritol 4-phosphate by 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, a new … T Kuzuyama, M Takagi, K Kaneda, T Dairi, H Seto Tetrahedron Letters 41 (5), 703-706, 2000 | 168 | 2000 |
Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid … T Kuzuyama, S Takahashi, M Takagi, H Seto Journal of Biological Chemistry 275 (26), 19928-19932, 2000 | 162 | 2000 |
Genome mining for sesterterpenes using bifunctional terpene synthases reveals a unified intermediate of di/sesterterpenes Y Ye, A Minami, A Mandi, C Liu, T Taniguchi, T Kuzuyama, K Monde, ... Journal of the American Chemical Society 137 (36), 11846-11853, 2015 | 161 | 2015 |
Studies on the nonmevalonate pathway: conversion of 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol to its 2-phospho derivative by 4-(cytidine 5′-diphospho)-2-C-methyl-D … T Kuzuyama, M Takagi, K Kaneda, H Watanabe, T Dairi, H Seto Tetrahedron Letters 41 (16), 2925-2928, 2000 | 151 | 2000 |
Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities T Kumano, SB Richard, JP Noel, M Nishiyama, T Kuzuyama Bioorganic & medicinal chemistry 16 (17), 8117-8126, 2008 | 143 | 2008 |
Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis T Kuzuyama, H Seto Proceedings of the Japan Academy, Series B 88 (3), 41-52, 2012 | 141 | 2012 |