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Maria Chatzopoulou
Maria Chatzopoulou
UCB
在 ucb.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Aldose reductase enzyme and its implication to major health problems of the 21st century
P Alexiou, K Pegklidou, M Chatzopoulou, I Nicolaou, VJ Demopoulos
Current medicinal chemistry 16 (6), 734-752, 2009
2772009
RAGE: a multi-ligand receptor unveiling novel insights in health and disease
P Alexiou, M Chatzopoulou, K Pegklidou, VJ Demopoulos
Current medicinal chemistry 17 (21), 2232-2252, 2010
1792010
Curcumin analogues as possible anti-proliferative & anti-inflammatory agents
AM Katsori, M Chatzopoulou, K Dimas, C Kontogiorgis, A Patsilinakos, ...
European journal of medicinal chemistry 46 (7), 2722-2735, 2011
1152011
Novel aldose reductase inhibitors: a patent survey (2006–present)
M Chatzopoulou, P Alexiou, E Kotsampasakou, VJ Demopoulos
Expert opinion on therapeutic patents 22 (11), 1303-1323, 2012
512012
Development of aldose reductase inhibitors for the treatment of inflammatory disorders
M Chatzopoulou, K Pegklidou, N Papastavrou, VJ Demopoulos
Expert opinion on drug discovery 8 (11), 1365-1380, 2013
482013
Chemical proteomics and phenotypic profiling identifies the aryl hydrocarbon receptor as a molecular target of the utrophin modulator ezutromid
IVL Wilkinson, KJ Perkins, H Dugdale, L Moir, A Vuorinen, ...
Angewandte Chemie International Edition 59 (6), 2420-2428, 2020
432020
Toward the development of innovative bifunctional agents to induce differentiation and to promote apoptosis in leukemia: clinical candidates and perspectives
IS Vizirianakis, M Chatzopoulou, ID Bonovolias, I Nicolaou, ...
Journal of medicinal chemistry 53 (19), 6779-6810, 2010
352010
Structure–activity relations on [1-(3, 5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl] phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity …
M Chatzopoulou, E Mamadou, M Juskova, C Koukoulitsa, I Nicolaou, ...
Bioorganic & medicinal chemistry 19 (4), 1426-1433, 2011
292011
Pilot study to quantify palladium impurities in lead-like compounds following commonly used purification techniques
M Chatzopoulou, KS Madden, LJ Bromhead, C Greaves, TJ Cogswell, ...
ACS Medicinal Chemistry Letters 13 (2), 262-270, 2022
272022
From diagnosis to therapy in Duchenne muscular dystrophy
A Babbs, M Chatzopoulou, B Edwards, SE Squire, IVL Wilkinson, ...
Biochemical Society Transactions 48 (3), 813-821, 2020
272020
A biased agonist at immunometabolic receptor GPR84 causes distinct functional effects in macrophages
D Lucy, GSD Purvis, L Zeboudj, M Chatzopoulou, C Recio, CJR Bataille, ...
ACS Chemical Biology 14 (9), 2055-2064, 2019
272019
A fast entry to furanoditerpenoid-based Hedgehog signaling inhibitors: identifying essential structural features
M Chatzopoulou, A Antoniou, EN Pitsinos, M Bantzi, SD Koulocheri, ...
Organic letters 16 (12), 3344-3347, 2014
262014
2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy
A Babbs, A Berg, M Chatzopoulou, KE Davies, SG Davies, B Edwards, ...
Journal of Medicinal Chemistry 63 (14), 7880-7891, 2020
232020
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl) phenol as a scaffold for improved membrane permeation
M Chatzopoulou, A Patsilinakos, T Vallianatou, MS Prnova, S Žakelj, ...
Bioorganic & Medicinal Chemistry 22 (7), 2194-2207, 2014
222014
1-Hydroxypyrazole as a bioisostere of the acetic acid moiety in a series of aldose reductase inhibitors
N Papastavrou, M Chatzopoulou, K Pegklidou, I Nicolaou
Bioorganic & medicinal chemistry 21 (17), 4951-4957, 2013
202013
The Dimroth rearrangement as a probable cause for structural misassignments in imidazo [1, 2-a] pyrimidines: A 15N-labelling study and an easy method for the determination of …
M Chatzopoulou, RF Martínez, NJ Willis, TDW Claridge, FX Wilson, ...
Tetrahedron 74 (38), 5280-5288, 2018
192018
Discovery and mechanism of action studies of 4, 6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy
A Vuorinen, IVL Wilkinson, M Chatzopoulou, B Edwards, SE Squire, ...
European Journal of Medicinal Chemistry 220, 113431, 2021
152021
Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: the case of trifluoroacetylation
N Papastavrou, M Chatzopoulou, J Ballekova, M Cappiello, R Moschini, ...
European Journal of Medicinal Chemistry 130, 328-335, 2017
152017
Synthesis of SMT022357 enantiomers and in vivo evaluation in a Duchenne muscular dystrophy mouse model
A Babbs, A Berg, M Chatzopoulou, KE Davies, SG Davies, B Edwards, ...
Tetrahedron 76 (2), 130819, 2020
132020
Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid
M Chatzopoulou, TDW Claridge, KE Davies, SG Davies, DJ Elsey, E Emer, ...
Journal of Medicinal Chemistry 63 (5), 2547-2556, 2019
132019
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