Complete biosynthesis of opioids in yeast S Galanie, K Thodey, IJ Trenchard, M Filsinger Interrante, CD Smolke Science 349 (6252), 1095-1100, 2015 | 1111 | 2015 |
A microbial biomanufacturing platform for natural and semisynthetic opioids K Thodey, S Galanie, CD Smolke Nature chemical biology 10 (10), 837-844, 2014 | 324 | 2014 |
Malleability of the SARS-CoV-2 3CL Mpro active-site cavity facilitates binding of clinical antivirals DW Kneller, S Galanie, G Phillips, HM O'Neill, L Coates, A Kovalevsky Structure 28 (12), 1313-1320. e3, 2020 | 132 | 2020 |
High-throughput virtual screening and validation of a sars-cov-2 main protease noncovalent inhibitor A Clyde, S Galanie, DW Kneller, H Ma, Y Babuji, B Blaiszik, A Brace, ... Journal of chemical information and modeling 62 (1), 116-128, 2021 | 104 | 2021 |
Mesoscale porous silica as drug delivery vehicles: Synthesis, characterization, and pH-sensitive release profiles P DeMuth, M Hurley, C Wu, S Galanie, MR Zachariah, P DeShong Microporous and Mesoporous Materials 141 (1-3), 128-134, 2011 | 82 | 2011 |
Engineering biosynthetic enzymes for industrial natural product synthesis S Galanie, D Entwistle, J Lalonde Natural Product Reports 37 (8), 1122-1143, 2020 | 71 | 2020 |
Optimization of yeast-based production of medicinal protoberberine alkaloids S Galanie, CD Smolke Microbial cell factories 14, 1-13, 2015 | 71 | 2015 |
Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2 BC Sanders, S Pokhrel, AD Labbe, II Mathews, CJ Cooper, RB Davidson, ... Nature Communications 14 (1), 1733, 2023 | 50 | 2023 |
Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Protease DW Kneller, H Li, S Galanie, G Phillips, A Labbé, KL Weiss, Q Zhang, ... Journal of medicinal chemistry 64 (23), 17366-17383, 2021 | 47 | 2021 |
Hit Expansion of a Noncovalent SARS-CoV-2 Main Protease Inhibitor J Glaser, A Sedova, S Galanie, DW Kneller, RB Davidson, E Maradzike, ... ACS pharmacology & translational science 5 (4), 255-265, 2022 | 23 | 2022 |
Benzylisoquinoline alkaloids (bia) producing microbes, and methods of making and using the same CD Smolke, C Thodey, I Trenchard, S Galanie US Patent 9,534,241, 2017 | 22 | 2017 |
Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro MA Hameedi, E T. Prates, MR Garvin, II Mathews, BK Amos, ... Nature Communications 13 (1), 5285, 2022 | 21 | 2022 |
Molecular tools for chemical biotechnology S Galanie, MS Siddiqui, CD Smolke Current opinion in biotechnology 24 (6), 1000-1009, 2013 | 16 | 2013 |
Benzylisoquinoline alkaloids (bia) producing microbes, and methods of making and using the same CD Smolke, C Thodey, I Trenchard, S Galanie US Patent 10,017,799, 2018 | 13 | 2018 |
AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2 RP Joshi, KJ Schultz, JW Wilson, A Kruel, RA Varikoti, CJ Kombala, ... Journal of Chemical Information and Modeling 63 (5), 1438-1453, 2023 | 11 | 2023 |
Metabolomic Patterns of Septoria Canker Resistant and Susceptible Populus trichocarpa Genotypes 24 Hours Postinoculation RR Lenz, KB Louie, KL Søndreli, SS Galanie, JG Chen, W Muchero, ... Phytopathology® 111 (11), 2052-2066, 2021 | 8 | 2021 |
Complete absence of thebaine biosynthesis under home-brew fermentation conditions D Endy, S Galanie, CD Smolke bioRxiv, 024299, 2015 | 7 | 2015 |
Engineered glycosyltransferases and steviol glycoside glucosylation methods J Vroom, SS Galanie, N Dellas, J Liang, J Liu, D Entwistle, CD Moffett US Patent App. 15/886,094, 2018 | 6 | 2018 |
An orally administered enzyme therapeutic for homocystinuria that suppresses homocysteine by metabolizing methionine in the gastrointestinal tract K Skvorak, V Mitchell, L Teadt, KA Franklin, HO Lee, N Kruse, ... Molecular Genetics and Metabolism 139 (4), 107653, 2023 | 4 | 2023 |
Engineered glycosyltransferases and steviol glycoside glucosylation methods J Vroom, SS Galanie, J Liang, J Liu, N Dellas, MA Mayo, D Entwistle US Patent App. 16/514,578, 2020 | 4 | 2020 |