Organic Carbamates in Drug Design and Medicinal Chemistry AK Ghosh, M Brindisi Journal of medicinal chemistry 58 (7), 2895-2940, 2015 | 685 | 2015 |
Developing β‐secretase inhibitors for treatment of Alzheimer’s disease AK Ghosh, M Brindisi, J Tang Journal of neurochemistry 120, 71-83, 2012 | 343 | 2012 |
Drug development and medicinal chemistry efforts toward SARS‐coronavirus and Covid‐19 therapeutics AK Ghosh, M Brindisi, D Shahabi, ME Chapman, AD Mesecar ChemMedChem 15 (11), 907-932, 2020 | 281 | 2020 |
Urea derivatives in modern drug discovery and medicinal chemistry AK Ghosh, M Brindisi Journal of Medicinal Chemistry 63 (6), 2751-2788, 2019 | 243 | 2019 |
Multitarget compounds bearing tacrine-and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease L Ismaili, B Refouvelet, M Benchekroun, S Brogi, M Brindisi, S Gemma, ... Progress in neurobiology 151, 4-34, 2017 | 185 | 2017 |
The Curtius rearrangement: mechanistic insight and recent applications in natural product syntheses AK Ghosh, A Sarkar, M Brindisi Organic & biomolecular chemistry 16 (12), 2006-2027, 2018 | 116 | 2018 |
Discovery of a New Class of Potential Multifunctional Atypical Antipsychotic Agents Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors … S Butini, S Gemma, G Campiani, S Franceschini, F Trotta, M Borriello, ... Journal of medicinal chemistry 52 (1), 151-169, 2009 | 102 | 2009 |
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases S Maramai, S Gemma, S Brogi, G Campiani, S Butini, H Stark, M Brindisi Frontiers in Neuroscience 10, 451, 2016 | 96 | 2016 |
Design, synthesis, and structure–activity relationship studies of 4-quinolinyl-and 9-acrydinylhydrazones as potent antimalarial agents C Fattorusso, G Campiani, G Kukreja, M Persico, S Butini, MP Romano, ... Journal of medicinal chemistry 51 (5), 1333-1343, 2008 | 96 | 2008 |
Old but gold: tracking the new guise of histone deacetylase 6 (HDAC6) enzyme as a biomarker and therapeutic target in rare diseases M Brindisi, AP Saraswati, S Brogi, S Gemma, S Butini, G Campiani Journal of medicinal chemistry 63 (1), 23-39, 2019 | 95 | 2019 |
The Curtius rearrangement: applications in modern drug discovery and medicinal chemistry AK Ghosh, M Brindisi, A Sarkar ChemMedChem 13 (22), 2351-2373, 2018 | 91 | 2018 |
Achmatowicz reaction and its application in the syntheses of bioactive molecules AK Ghosh, M Brindisi RSC Advances 6 (112), 111564-111598, 2016 | 87 | 2016 |
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain M Brindisi, S Maramai, S Gemma, S Brogi, A Grillo, L Di Cesare Mannelli, ... Journal of medicinal chemistry 59 (6), 2612-2632, 2016 | 78 | 2016 |
Polypharmacology of dopamine receptor ligands S Butini, K Nikolic, S Kassel, H Brückmann, S Filipic, D Agbaba, S Gemma, ... Progress in neurobiology 142, 68-103, 2016 | 77 | 2016 |
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking M Brindisi, S Brogi, N Relitti, A Vallone, S Butini, S Gemma, E Novellino, ... Scientific reports 5, 9705, 2015 | 76 | 2015 |
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas T Khan, N Relitti, M Brindisi, S Magnano, D Zisterer, S Gemma, S Butini, ... Medicinal research reviews 40 (3), 1002-1060, 2020 | 72 | 2020 |
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents S Gemma, C Camodeca, M Brindisi, S Brogi, G Kukreja, S Kunjir, ... Journal of medicinal chemistry 55 (23), 10387-10404, 2012 | 72 | 2012 |
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors S Butini, G Campiani, M Borriello, S Gemma, A Panico, M Persico, ... Journal of medicinal chemistry 51 (11), 3154-3170, 2008 | 69 | 2008 |
Pyrroloquinoxaline hydrazones as fluorescent probes for amyloid fibrils S Gemma, L Colombo, G Forloni, L Savini, C Fracasso, S Caccia, ... Organic & biomolecular chemistry 9 (14), 5137-5148, 2011 | 61 | 2011 |
Computational tool for fast in silico evaluation of hERG K+ channel affinity G Chemi, S Gemma, G Campiani, S Brogi, S Butini, M Brindisi Frontiers in Chemistry 5, 7, 2017 | 60 | 2017 |