The tail of integrins, talin, and kindlins M Moser, KR Legate, R Zent, R Fässler Science 324 (5929), 895-899, 2009 | 934 | 2009 |
The talin head domain binds to integrin β subunit cytoplasmic tails and regulates integrin activation DA Calderwood, R Zent, R Grant, DJG Rees, RO Hynes, MH Ginsberg Journal of Biological Chemistry 274 (40), 28071-28074, 1999 | 899 | 1999 |
Integrin β1 signaling is necessary for transforming growth factor-β activation of p38MAPK and epithelial plasticity NA Bhowmick, R Zent, M Ghiassi, M McDonnell, HL Moses Journal of Biological Chemistry 276 (50), 46707-46713, 2001 | 522 | 2001 |
Kindlin-2 controls bidirectional signaling of integrins E Montanez, S Ussar, M Schifferer, M Bösl, R Zent, M Moser, R Fässler Genes & development 22 (10), 1325-1330, 2008 | 488 | 2008 |
Extracellular rigidity sensing by talin isoform-specific mechanical linkages K Austen, P Ringer, A Mehlich, A Chrostek-Grashoff, C Kluger, C Klingner, ... Nature cell biology 17 (12), 1597-1606, 2015 | 357 | 2015 |
Sirt1 activation protects the mouse renal medulla from oxidative injury W He, Y Wang, MZ Zhang, L You, LS Davis, H Fan, HC Yang, AB Fogo, ... The Journal of clinical investigation 120 (4), 1056-1068, 2010 | 344 | 2010 |
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin M Theodosiou, M Widmaier, RT Böttcher, E Rognoni, M Veelders, ... Elife 5, e10130, 2016 | 259 | 2016 |
Vinculin controls talin engagement with the actomyosin machinery P Atherton, B Stutchbury, DY Wang, D Jethwa, R Tsang, ... Nature communications 6 (1), 10038, 2015 | 224 | 2015 |
β1 integrin expression by podocytes is required to maintain glomerular structural integrity A Pozzi, G Jarad, GW Moeckel, S Coffa, X Zhang, L Gewin, V Eremina, ... Developmental biology 316 (2), 288-301, 2008 | 222 | 2008 |
Characterization of 5, 6-and 8, 9-epoxyeicosatrienoic acids (5, 6-and 8, 9-EET) as potent in vivo angiogenic lipids A Pozzi, I Macias-Perez, T Abair, S Wei, Y Su, R Zent, JR Falck, ... Journal of Biological Chemistry 280 (29), 27138-27146, 2005 | 215 | 2005 |
Global analysis reveals the complexity of the human glomerular extracellular matrix R Lennon, A Byron, JD Humphries, MJ Randles, A Carisey, S Murphy, ... Journal of the American Society of Nephrology 25 (5), 939-951, 2014 | 213 | 2014 |
Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance X Tian, JJ Kim, SM Monkley, N Gotoh, R Nandez, K Soda, K Inoue, ... The Journal of clinical investigation 124 (3), 1098-1113, 2014 | 166 | 2014 |
Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression RS Muraoka-Cook, I Shin, JY Yi, E Easterly, MH Barcellos-Hoff, ... Oncogene 25 (24), 3408-3423, 2006 | 164 | 2006 |
Distinct domains of CD98hc regulate integrins and amino acid transport CA Fenczik, R Zent, M Dellos, DA Calderwood, J Satriano, C Kelly, ... Journal of Biological Chemistry 276 (12), 8746-8752, 2001 | 164 | 2001 |
Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel K Nakagawa, VR Holla, Y Wei, WH Wang, A Gatica, S Wei, S Mei, ... The Journal of clinical investigation 116 (6), 1696-1702, 2006 | 163 | 2006 |
Transforming growth factor β induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton SE Wang, B Xiang, R Zent, V Quaranta, A Pozzi, CL Arteaga Cancer research 69 (2), 475-482, 2009 | 161 | 2009 |
Integrin-linked kinase is an adaptor with essential functions during mouse development A Lange, SA Wickström, M Jakobson, R Zent, K Sainio, R Fässler Nature 461 (7266), 1002-1006, 2009 | 159 | 2009 |
Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo R Rao, R Redha, I Macias-Perez, Y Su, C Hao, R Zent, MD Breyer, ... Journal of Biological Chemistry 282 (23), 16959-16968, 2007 | 149 | 2007 |
Progression of chronic kidney disease: too much cellular talk causes damage L Gewin, R Zent, A Pozzi Kidney international 91 (3), 552-560, 2017 | 145 | 2017 |
Integrins in kidney disease A Pozzi, R Zent Journal of the American Society of Nephrology 24 (7), 1034-1039, 2013 | 139 | 2013 |