| Site-specific PEGylation of a lysine-deficient TNF-α with full bioactivity Y Yamamoto, Y Tsutsumi, Y Yoshioka, T Nishibata, K Kobayashi, ... Nature biotechnology 21 (5), 546-552, 2003 | 267 | 2003 |
| The use of PVP as a polymeric carrier to improve the plasma half-life of drugs Y Kaneda, Y Tsutsumi, Y Yoshioka, H Kamada, Y Yamamoto, H Kodaira, ... Biomaterials 25 (16), 3259-3266, 2004 | 244 | 2004 |
| Synthesis of a poly (vinylpyrrolidone-co-dimethyl maleic anhydride) co-polymer and its application for renal drug targeting H Kamada, Y Tsutsumi, K Sato-Kamada, Y Yamamoto, Y Yoshioka, ... nature biotechnology 21 (4), 399-404, 2003 | 150 | 2003 |
| Leaky gut: effect of dietary fiber and fats on microbiome and intestinal barrier H Usuda, T Okamoto, K Wada International journal of molecular sciences 22 (14), 7613, 2021 | 146 | 2021 |
| Thrombomodulin: a bifunctional modulator of inflammation and coagulation in sepsis T Okamoto, H Tanigami, K Suzuki, M Shimaoka Critical care research and practice 2012 (1), 614545, 2012 | 108 | 2012 |
| Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression T Okamoto, Y Takagi, E Kawamoto, EJ Park, H Usuda, K Wada, ... Experimental cell research 367 (2), 264-273, 2018 | 97 | 2018 |
| Design of a pH-sensitive polymeric carrier for drug release and its application in cancer therapy H Kamada, Y Tsutsumi, Y Yoshioka, Y Yamamoto, H Kodaira, S Tsunoda, ... Clinical cancer research 10 (7), 2545-2550, 2004 | 90 | 2004 |
| Functionalization of tumor necrosis factor-α using phage display technique and PEGylation improves its antitumor therapeutic window H Shibata, Y Yoshioka, S Ikemizu, K Kobayashi, Y Yamamoto, Y Mukai, ... Clinical cancer research 10 (24), 8293-8300, 2004 | 85 | 2004 |
| The targeting of anionized polyvinylpyrrolidone to the renal system H Kodaira, Y Tsutsumi, Y Yoshioka, H Kamada, Y Kaneda, Y Yamamoto, ... Biomaterials 25 (18), 4309-4315, 2004 | 83 | 2004 |
| Connexins and integrins in exosomes M Shimaoka, E Kawamoto, A Gaowa, T Okamoto, EJ Park Cancers 11 (1), 106, 2019 | 75 | 2019 |
| Optimal construction of non-immune scFv phage display libraries from mouse bone marrow and spleen established to select specific scFvs efficiently binding to antigen T Okamoto, Y Mukai, Y Yoshioka, H Shibata, M Kawamura, Y Yamamoto, ... Biochemical and biophysical research communications 323 (2), 583-591, 2004 | 73 | 2004 |
| The role of gap junction-mediated endothelial cell–cell interaction in the crosstalk between inflammation and blood coagulation T Okamoto, K Suzuki International journal of molecular sciences 18 (11), 2254, 2017 | 69 | 2017 |
| Optimal site-specific PEGylation of mutant TNF-α improves its antitumor potency Y Yoshioka, Y Tsutsumi, S Ikemizu, Y Yamamoto, H Shibata, T Nishibata, ... Biochemical and biophysical research communications 315 (4), 808-814, 2004 | 67 | 2004 |
| Connexin32 is expressed in vascular endothelial cells and participates in gap-junction intercellular communication T Okamoto, M Akiyama, M Takeda, EC Gabazza, T Hayashi, K Suzuki Biochemical and biophysical research communications 382 (2), 264-268, 2009 | 64 | 2009 |
| Poly (vinylpyrrolidone-co-dimethyl maleic acid) as a novel renal targeting carrier Y Yamamoto, Y Tsutsumi, Y Yoshioka, H Kamada, K Sato-Kamada, ... Journal of controlled release 95 (2), 229-237, 2004 | 64 | 2004 |
| Gap junction-mediated regulation of endothelial cellular stiffness T Okamoto, E Kawamoto, Y Takagi, N Akita, T Hayashi, EJ Park, K Suzuki, ... Scientific reports 7 (1), 6134, 2017 | 58 | 2017 |
| Effect of copper addition on the β-phase formation rate in FeSi2 thermoelectric materials I Yamauchi, A Suganuma, T Okamoto, I Ohnaka Journal of materials science 32, 4603-4611, 1997 | 53 | 1997 |
| Anti‐integrin therapy for multiple sclerosis E Kawamoto, S Nakahashi, T Okamoto, H Imai, M Shimaoka Autoimmune diseases 2012 (1), 357101, 2012 | 52 | 2012 |
| Creation of novel cell-penetrating peptides for intracellular drug delivery using systematic phage display technology originated from Tat transduction domain H Kamada, T Okamoto, M Kawamura, H Shibata, Y Abe, A Ohkawa, ... Biological and Pharmaceutical Bulletin 30 (2), 218-223, 2007 | 47 | 2007 |
| Soluble programmed death-ligand 1 rather than PD-L1 on tumor cells effectively predicts metastasis and prognosis in soft tissue sarcomas K Asanuma, T Nakamura, A Hayashi, T Okamoto, T Iino, Y Asanuma, ... Scientific reports 10 (1), 9077, 2020 | 46 | 2020 |
