| Single‐cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT‐related genes in metastatic prostate cancer CL Chen, D Mahalingam, P Osmulski, RR Jadhav, CM Wang, RJ Leach, ... The Prostate 73 (8), 813-826, 2013 | 285 | 2013 |
| Proline-and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity M Gaczynska, PA Osmulski, Y Gao, MJ Post, M Simons Biochemistry 42 (29), 8663-8670, 2003 | 156 | 2003 |
| The central unit within the 19S regulatory particle of the proteasome R Rosenzweig, PA Osmulski, M Gaczynska, MH Glickman Nature structural & molecular biology 15 (6), 573-580, 2008 | 155 | 2008 |
| Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat KA Rodriguez, YH Edrey, P Osmulski, M Gaczynska, R Buffenstein PloS one 7 (5), e35890, 2012 | 129 | 2012 |
| Structure, function and physiological role of Chironomus haemoglobin PA Osmulski, W Leyko Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 85 …, 1986 | 127 | 1986 |
| Caretaker or undertaker? The role of the proteasome in aging M Gaczynska, PA Osmulski, WF Ward Mechanisms of ageing and development 122 (3), 235-254, 2001 | 114 | 2001 |
| A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the α-ring channel PA Osmulski, M Hochstrasser, M Gaczynska Structure 17 (8), 1137-1147, 2009 | 109 | 2009 |
| Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease YH Edrey, DX Medina, M Gaczynska, PA Osmulski, S Oddo, A Caccamo, ... Neurobiology of aging 34 (10), 2352-2360, 2013 | 101 | 2013 |
| Atomic force microscopy reveals two conformations of the 20 S proteasome from fission yeast PA Osmulski, M Gaczynska Journal of Biological Chemistry 275 (18), 13171-13174, 2000 | 79 | 2000 |
| The growth-suppressive function of the polycomb group protein polyhomeotic is mediated by polymerization of its sterile alpha motif (SAM) domain AK Robinson, BZ Leal, LV Chadwell, R Wang, U Ilangovan, Y Kaur, ... Journal of Biological Chemistry 287 (12), 8702-8713, 2012 | 76 | 2012 |
| Nanoenzymology of the 20S proteasome: proteasomal actions are controlled by the allosteric transition PA Osmulski, M Gaczynska Biochemistry 41 (22), 7047-7053, 2002 | 76 | 2002 |
| AFM of biological complexes: what can we learn? M Gaczynska, PA Osmulski Current opinion in colloid & interface science 13 (5), 351-367, 2008 | 71 | 2008 |
| Small-molecule inhibitors of proteasome activity M Gaczynska, PA Osmulski Ubiquitin-Proteasome Protocols, 1-22, 2005 | 70 | 2005 |
| A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition KA Rodriguez, PA Osmulski, A Pierce, ST Weintraub, M Gaczynska, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (11 …, 2014 | 67 | 2014 |
| Small molecule modulation of proteasome assembly E Njomen, PA Osmulski, CL Jones, M Gaczynska, JJ Tepe Biochemistry 57 (28), 4214-4224, 2018 | 66 | 2018 |
| EpCAM-regulated transcription exerts influences on nanomechanical properties of endometrial cancer cells that promote epithelial-to-mesenchymal transition YT Hsu, P Osmulski, Y Wang, YW Huang, L Liu, J Ruan, VX Jin, NB Kirma, ... Cancer research 76 (21), 6171-6182, 2016 | 57 | 2016 |
| The proteasome in health and disease E Jankowska, J Stoj, P Karpowicz, PA Osmulski, M Gaczynska Current pharmaceutical design 19 (6), 1010-1028, 2013 | 56 | 2013 |
| Phosphorylation by Nek1 regulates opening and closing of voltage dependent anion channel 1 Y Chen, M Gaczynska, P Osmulski, R Polci, DJ Riley Biochemical and biophysical research communications 394 (3), 798-803, 2010 | 56 | 2010 |
| Rapamycin allosterically inhibits the proteasome PA Osmulski, M Gaczynska Molecular pharmacology 84 (1), 104-113, 2013 | 54 | 2013 |
| Single-cell proteomic profiling identifies combined AXL and JAK1 inhibition as a novel therapeutic strategy for lung cancer JA Taverna, CN Hung, DT DeArmond, M Chen, CL Lin, PA Osmulski, ... Cancer research 80 (7), 1551-1563, 2020 | 51 | 2020 |
