关注
Felix Yeh
Felix Yeh
其他姓名Felix L. Yeh
Director
在 gene.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
SV2 is the protein receptor for botulinum neurotoxin A
M Dong, F Yeh, WH Tepp, C Dean, EA Johnson, R Janz, ER Chapman
Science 312 (5773), 592-596, 2006
9482006
TREM2 binds to apolipoproteins, including APOE and CLU/APOJ, and thereby facilitates uptake of amyloid-beta by microglia
FL Yeh, Y Wang, I Tom, LC Gonzalez, M Sheng
Neuron 91 (2), 328-340, 2016
8782016
TREM2, microglia, and neurodegenerative diseases
FL Yeh, DV Hansen, M Sheng
Trends in molecular medicine 23 (6), 512-533, 2017
4112017
SV2 mediates entry of tetanus neurotoxin into central neurons
FL Yeh, M Dong, J Yao, WH Tepp, G Lin, EA Johnson, ER Chapman
PLoS pathogens 6 (11), e1001207, 2010
1622010
Biophysical characterization of styryl dye-membrane interactions
Y Wu, FL Yeh, F Mao, ER Chapman
Biophysical journal 97 (1), 101-109, 2009
872009
Interneuronal transfer and distal action of tetanus toxin and botulinum neurotoxins A and D in central neurons
E Bomba-Warczak, JD Vevea, JM Brittain, A Figueroa-Bernier, WH Tepp, ...
Cell reports 16 (7), 1974-1987, 2016
782016
All three components of the neuronal SNARE complex contribute to secretory vesicle docking
Y Wu, Y Gu, MK Morphew, J Yao, FL Yeh, M Dong, ER Chapman
Journal of Cell Biology 198 (3), 323-330, 2012
352012
A Phase 1 study of GDC‐0134, a dual leucine zipper kinase inhibitor, in ALS
JS Katz, JD Rothstein, ME Cudkowicz, A Genge, B Oskarsson, AB Hains, ...
Annals of clinical and translational neurology 9 (1), 50-66, 2022
302022
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia
M Kurnellas, A Mitra, T Schwabe, R Paul, AE Arrant, ED Roberson, ...
Journal of Translational Medicine 21 (1), 387, 2023
192023
Retargeted clostridial neurotoxins as novel agents for treating chronic diseases
FL Yeh, Y Zhu, WH Tepp, EA Johnson, PJ Bertics, ER Chapman
Biochemistry 50 (48), 10419-10421, 2011
172011
A phase 1 study of AL002 in healthy volunteers
M Ward, H Long, T Schwabe, H Rhinn, I Tassi, SV Salazar, A Rychkova, ...
Alzheimer's & Dementia 17, e054669, 2021
102021
Multiple doses of an anti-FGFR1/KLB bispecific antibody (BFKB8488A) are associated with a decrease in hepatic fat in patients with NAFLD
R Kunder, F Yeh, LW Chinn, A Dash, N Lewin-Koh, N Kim, J Fredrickson, ...
Hepatology 70 (6), 1493A-1493A, 2019
82019
Btbd11 is an inhibitory interneuron specific synaptic scaffolding protein that supports excitatory synapse structure and function
AM Bygrave, A Sengupta, EP Jackert, M Ahmed, B Adenuga, E Nelson, ...
Biorxiv, 2021.11. 01.466782, 2021
72021
INVOKE‐2: A phase 2 randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of AL002 in participants with early Alzheimer’s disease
R Paul, S Jackson, M Ward, A Joshi, A Castro, FL Yeh, Y Liao, G Morrison
Alzheimer's & Dementia 17, e054615, 2021
52021
A BISPECIFIC ANTIBODY TO FGFR1/KLB, BFKB8488A, IMPROVES LIPID PROFILE, MARKERS OF FIBROGENESIS AND LIVER HEALTH IN PATIENTS WITH TYPE 2 DIABETES-PRELIMINARY RESULTS FROM A …
C Wong, F Yeh, L Chinn, A Dash, N Lewin-Koh, K Yoshida, S Chen, ...
HEPATOLOGY 70, 1358A-1359A, 2019
52019
Btbd11 supports cell-type-specific synaptic function
AM Bygrave, A Sengupta, EP Jackert, M Ahmed, B Adenuga, E Nelson, ...
Cell reports 42 (6), 2023
42023
Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer’s disease
H Long, A Simmons, A Mayorga, B Burgess, T Nguyen, B Budda, ...
Alzheimer's Research & Therapy 16 (1), 235, 2024
32024
A Phase 1 Study of AL003 in Healthy Volunteers and Participants with Alzheimer’s disease (P5-3.002)
D Maslyar, R Paul, H Long, H Rhinn, I Tassi, G Morrison, F Yeh, ...
Neurology 98 (18_supplement), 3582, 2022
32022
AL001 restores CSF PGRN levels and normalizes disease‐associated biomarkers in individuals with frontotemporal dementia due to heterozygous mutations in the progranulin gene …
BA Haynes, H Rhinn, FL Yeh, H Long, M Ward, M Hagey, O Siddiqui, ...
Alzheimer's & Dementia 16, e046114, 2020
32020
A Phase 1 Study of AL002 in Healthy Volunteers (P5-3.004)
M Ward, R Paul, H Long, H Rhinn, A Rychkova, G Tu, C Barner, S Salazar, ...
Neurology 98 (18_supplement), 3133, 2022
22022
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