Selenocysteine variant of human Peroxiredoxin 2 is more active than the wild type enzyme A Andor, ZA Pató, M Mohanraj, B Biri-Kovács, A Kolonics, Q Cheng, ... Free Radical Biology and Medicine 218, 23, 2024 | | 2024 |
Beyond reduction: unveiling TRP14’s dual role in cysteine homeostasis and redox dynamics P Martí-Andrés, I Finamor, I Torres, S Pérez, S Rius-Pérez, H Colino-Lage, ... Free Radical Biology and Medicine 218, 8, 2024 | | 2024 |
TRP14 is the rate-limiting enzyme for intracellular cystine reduction and regulates proteome cysteinylation P Martí-Andrés, I Finamor, I Torres-Cuevas, S Pérez, S Rius-Pérez, ... The EMBO Journal, 1-24, 2024 | | 2024 |
Ancient loss of catalytic selenocysteine spurred convergent adaptation in a mammalian oxidoreductase J Rees, G Sarangi, Q Cheng, M Floor, AM Andrés, B Oliva Miguel, ... Genome Biology and Evolution 16 (3), evae041, 2024 | | 2024 |
Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology L Zeisel, JG Felber, KC Scholzen, C Schmitt, AJ Wiegand, L Komissarov, ... Journal of the American Chemical Society 146 (8), 5204-5214, 2024 | 2 | 2024 |
Arsenic exposure and increased C-reactive protein are independently associated with lower erythrocyte glutathione peroxidase activity in Bangladeshi children DM Cheff, H Skröder, E Akhtar, Q Cheng, MD Hall, R Raqib, M Kippler, ... Redox Biochemistry and Chemistry 5, 100015, 2023 | | 2023 |
Beware of the kat among the proteins L Coppo, A Scholz, E Nolan, M Hernandez, X Wang, P Mishra, R Schnell, ... Free Radical Biology and Medicine 208, S118-S119, 2023 | | 2023 |
Selenium in control of cell death–unresolved questions regarding the potential roles of glutathione peroxidases and thioredoxin reductases E Arner Free Radical Biology and Medicine 208, S10, 2023 | | 2023 |
Clozapine suppresses NADPH oxidase activation, counteracts cytosolic H2O2, and triggers early onset mitochondrial dysfunction during adipogenesis of human liposarcoma SW872 cells G Blandino, M Fiorani, B Canonico, R De Matteis, A Guidarelli, ... Redox Biology 67, 102915, 2023 | 1 | 2023 |
TXNL1 has dual functions as a redox active thioredoxin-like protein as well as an ATP-and redox-independent chaperone A Andor, M Mohanraj, ZA Pató, K Úri, B Biri-Kovács, Q Cheng, ESJ Arnér Redox Biology 67, 102897, 2023 | 4 | 2023 |
The anticancer compounds auranofin, TRi-1 and TRi-2 have distinct cytotoxicity profiles with regards to thioredoxin reductase inhibition R Gencheva, Q Cheng, E Arner Free Radical Biology and Medicine 208, S102-S103, 2023 | | 2023 |
Piperazine-fused cyclic disulfides: high-performance bioreduction-activated cores for bifunctional probes and reagents L Zeisel, JG Felber, KC Scholzen, C Schmitt, AJ Wiegand, L Komissarov, ... | | 2023 |
Cardiolipin drives the catalytic activity of GPX4 on membranes: Insights from the R152H mutant A Roveri, F Di Giacinto, M Rossetto, G Cozza, Q Cheng, G Miotto, ... Redox Biology 64, 102806, 2023 | 2 | 2023 |
Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4 DM Cheff, Q Cheng, H Guo, J Travers, C Klumpp-Thomas, M Shen, ... Redox Biology 63, 102719, 2023 | 11 | 2023 |
Novel gold (III)-dithiocarbamate complex targeting bacterial thioredoxin reductase: Antimicrobial activity, synergy, toxicity, and mechanistic insights C Ratia, V Ballén, Y Gabasa, RG Soengas, M Velasco-de Andrés, ... Frontiers in Microbiology 14, 1198473, 2023 | 4 | 2023 |
The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1 DM Cheff, C Huang, KC Scholzen, R Gencheva, MH Ronzetti, Q Cheng, ... Redox Biology 62, 102703, 2023 | 52 | 2023 |
Is there a substrate specificity of glutathione peroxidase isoforms? M Schwarz, Q Cheng, A Löser, ESJ Arnér, AP Kipp Free Radical Biology and Medicine 201, 37-38, 2023 | | 2023 |
TRP14 is the cellular cystine reductase and also reduces cysteinylated proteins P Martí-Andrés, S Pérez, S Rius-Pérez, I Torres-Cuevas, H Colino-Lage, ... Free Radical Biology and Medicine 201, 15, 2023 | | 2023 |
Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides M Schwarz, A Löser, Q Cheng, M Wichmann-Costaganna, P Schädel, ... Redox Biology 59, 102593, 2023 | 17 | 2023 |
Bifunctional, piperazine-fused cyclic disulfides for oxidoreductase-activated cellular proagents L Zeisel, JG Felber, KC Scholzen, C Schmitt, AJ Wiegand, L Komissarov, ... | 2 | 2023 |