关注
Samarth Hegde
Samarth Hegde
Postdoctoral Fellow, Merad Lab, Icahn School of Medicine at Mount Sinai
在 go.wustl.edu 的电子邮件经过验证 - 首页
标题
引用次数
年份
Single cell view of tumor microenvironment gradients in pleural mesothelioma
B Giotti, K Dolasia, W Zhao, P Cai, R Sweeney, E Merritt, E Kiner, GS Kim, ...
Cancer Discovery, 2024
12024
An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis
NM LaMarche, S Hegde, MD Park, BB Maier, L Troncoso, J Le Berichel, ...
Nature 625 (7993), 166-174, 2024
172024
Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors
S Hegde, B Giotti, BY Soong, L Halasz, J Le Berichel, A Magen, ...
bioRxiv, 2024.06. 24.600383, 2024
2024
650 Neoadjuvant ezabenlimab or pembrolizumab in combination with an anti-SIRPα antibody in resectable colorectal cancer
N Lucas, N Venturini, S Hegde, R Mattiuz, C Hennequin, J Le Berichel, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma
A Magen, P Hamon, N Fiaschi, BY Soong, MD Park, R Mattiuz, E Humblin, ...
Nature medicine 29 (6), 1389-1399, 2023
812023
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer
MD Park, I Reyes-Torres, J LeBerichel, P Hamon, NM LaMarche, ...
Nature immunology 24 (5), 792-801, 2023
502023
Abstract CT199: Rescuing response to ICI by blocking the type-2 immune axis in patients with NSCLC progressing on immunotherapy: A phase 1b/2 trial of dupilumab administered …
TU Marron, NM LaMarche, MD Park, S Hegde, B Fitzgerald, C Hennequin, ...
Cancer Research 83 (8_Supplement), CT199-CT199, 2023
2023
On the biology and therapeutic modulation of macrophages and dendritic cells in cancer
MD Park, M Belabed, ST Chen, P Hamon, S Hegde, R Mattiuz, TU Marron, ...
Annual Review of Cancer Biology 7 (1), 291-311, 2023
62023
Single-cell immune multi-omics and repertoire analyses in pancreatic ductal adenocarcinoma reveal differential immunosuppressive mechanisms within different tumour …
S Sivakumar, A Jainarayanan, E Arbe-Barnes, MN Leathlobhair, ...
bioRxiv, 2023.08. 31.555730, 2023
12023
P2. 12-05 Cancer and Atopy: Parallel Drivers? IL-4 Blockade Synergizes with PD-L1 Blockade to Reverse Type-2Mediated Immunosuppression
TU Marron, B Maier, NM LaMarche, S Hegde, M Belabed, R Mattiuz, ...
Journal of Thoracic Oncology 17 (9), S153-S154, 2022
12022
Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade
A Magen, P Hamon, N Fiaschi, L Troncoso, E Humblin, D D’souza, ...
BioRxiv, 2022.06. 22.497216, 2022
102022
A phase 1b/2 trial of dupilumab given in conjunction with PD-(L) 1 blockade in the treatment of relapsed/refractory metastatic NSCLC.
BG Fitzgerald, TU Marron, N Hall, D O'Grady, N LaMarche, C Hennequin, ...
Journal of Clinical Oncology 40 (16_suppl), TPS9139-TPS9139, 2022
22022
MDSC: Markers, development, states, and unaddressed complexity
S Hegde, AM Leader, M Merad
Immunity 54 (5), 875-884, 2021
3632021
Pancreatic Cancer Immuno-oncology in the Era of Precision Medicine
S Hegde
Indian Journal of Surgical Oncology 12 (Suppl 1), 118-127, 2021
2021
TREM2 sensing of tumor cell efferocytosis promotes a macrophage molecular state that limits NK cell antitumor immunity
I Reyes-Torres, M Park, A Magen, P Hamon, ...
22021
Many paths to COVID-19 lymphocyte dysfunction
S Hegde
Nature Reviews Immunology 20 (7), 408-408, 2020
12020
Sinai Immunology Review Project
N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ...
Immunology of COVID-19: current state of the science. Immunity 52 (6), 910-941, 2020
732020
Immunology of COVID-19: current state of the science
N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ...
Immunity 52 (6), 910-941, 2020
18572020
Does asthma make COVID-19 worse?
S Hegde
Nature Reviews Immunology 20 (6), 352-352, 2020
222020
Dendritic cell paucity leads to dysfunctional immune surveillance in pancreatic cancer
S Hegde, VE Krisnawan, BH Herzog, C Zuo, MA Breden, BL Knolhoff, ...
Cancer cell 37 (3), 289-307. e9, 2020
3262020
系统目前无法执行此操作,请稍后再试。
文章 1–20