Single cell view of tumor microenvironment gradients in pleural mesothelioma B Giotti, K Dolasia, W Zhao, P Cai, R Sweeney, E Merritt, E Kiner, GS Kim, ... Cancer Discovery, 2024 | 1 | 2024 |
An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis NM LaMarche, S Hegde, MD Park, BB Maier, L Troncoso, J Le Berichel, ... Nature 625 (7993), 166-174, 2024 | 17 | 2024 |
Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors S Hegde, B Giotti, BY Soong, L Halasz, J Le Berichel, A Magen, ... bioRxiv, 2024.06. 24.600383, 2024 | | 2024 |
650 Neoadjuvant ezabenlimab or pembrolizumab in combination with an anti-SIRPα antibody in resectable colorectal cancer N Lucas, N Venturini, S Hegde, R Mattiuz, C Hennequin, J Le Berichel, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma A Magen, P Hamon, N Fiaschi, BY Soong, MD Park, R Mattiuz, E Humblin, ... Nature medicine 29 (6), 1389-1399, 2023 | 81 | 2023 |
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer MD Park, I Reyes-Torres, J LeBerichel, P Hamon, NM LaMarche, ... Nature immunology 24 (5), 792-801, 2023 | 50 | 2023 |
Abstract CT199: Rescuing response to ICI by blocking the type-2 immune axis in patients with NSCLC progressing on immunotherapy: A phase 1b/2 trial of dupilumab administered … TU Marron, NM LaMarche, MD Park, S Hegde, B Fitzgerald, C Hennequin, ... Cancer Research 83 (8_Supplement), CT199-CT199, 2023 | | 2023 |
On the biology and therapeutic modulation of macrophages and dendritic cells in cancer MD Park, M Belabed, ST Chen, P Hamon, S Hegde, R Mattiuz, TU Marron, ... Annual Review of Cancer Biology 7 (1), 291-311, 2023 | 6 | 2023 |
Single-cell immune multi-omics and repertoire analyses in pancreatic ductal adenocarcinoma reveal differential immunosuppressive mechanisms within different tumour … S Sivakumar, A Jainarayanan, E Arbe-Barnes, MN Leathlobhair, ... bioRxiv, 2023.08. 31.555730, 2023 | 1 | 2023 |
P2. 12-05 Cancer and Atopy: Parallel Drivers? IL-4 Blockade Synergizes with PD-L1 Blockade to Reverse Type-2Mediated Immunosuppression TU Marron, B Maier, NM LaMarche, S Hegde, M Belabed, R Mattiuz, ... Journal of Thoracic Oncology 17 (9), S153-S154, 2022 | 1 | 2022 |
Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade A Magen, P Hamon, N Fiaschi, L Troncoso, E Humblin, D D’souza, ... BioRxiv, 2022.06. 22.497216, 2022 | 10 | 2022 |
A phase 1b/2 trial of dupilumab given in conjunction with PD-(L) 1 blockade in the treatment of relapsed/refractory metastatic NSCLC. BG Fitzgerald, TU Marron, N Hall, D O'Grady, N LaMarche, C Hennequin, ... Journal of Clinical Oncology 40 (16_suppl), TPS9139-TPS9139, 2022 | 2 | 2022 |
MDSC: Markers, development, states, and unaddressed complexity S Hegde, AM Leader, M Merad Immunity 54 (5), 875-884, 2021 | 363 | 2021 |
Pancreatic Cancer Immuno-oncology in the Era of Precision Medicine S Hegde Indian Journal of Surgical Oncology 12 (Suppl 1), 118-127, 2021 | | 2021 |
TREM2 sensing of tumor cell efferocytosis promotes a macrophage molecular state that limits NK cell antitumor immunity I Reyes-Torres, M Park, A Magen, P Hamon, ... | 2 | 2021 |
Many paths to COVID-19 lymphocyte dysfunction S Hegde Nature Reviews Immunology 20 (7), 408-408, 2020 | 1 | 2020 |
Sinai Immunology Review Project N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ... Immunology of COVID-19: current state of the science. Immunity 52 (6), 910-941, 2020 | 73 | 2020 |
Immunology of COVID-19: current state of the science N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ... Immunity 52 (6), 910-941, 2020 | 1857 | 2020 |
Does asthma make COVID-19 worse? S Hegde Nature Reviews Immunology 20 (6), 352-352, 2020 | 22 | 2020 |
Dendritic cell paucity leads to dysfunctional immune surveillance in pancreatic cancer S Hegde, VE Krisnawan, BH Herzog, C Zuo, MA Breden, BL Knolhoff, ... Cancer cell 37 (3), 289-307. e9, 2020 | 326 | 2020 |