Epithelial Xbp1s Expression Leads to Distal Lung MUC5B Hyperproduction and Progression of Pulmonary Fibrosis Following Injury G Chen, L Sun, H Dang, K Hasegawa, AS Volmer, L Zhou, AA Deshmukh, ... C28. MORE THAN MEET THE EYE: NOVEL INSIGHTS IN IPF PATHOGENESIS, A5186-A5186, 2024 | | 2024 |
Transcriptional Pathways in Small Airway Basal Cells Define Niches of Goblet Cell Metaplasia in Asthma S Schworer, K Okuda, H Dang, M Markovetz, T Kato, T Asakura, G Chen, ... C19. CHARTING THE LUNG: INNOVATION IN MULTIOMICS, A5015-A5015, 2024 | | 2024 |
Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non–Cystic Fibrosis Bronchiectasis T Asakura, K Okuda, G Chen, H Dang, T Kato, Y Mikami, SA Schworer, ... American Journal of Respiratory and Critical Care Medicine 209 (4), 374-389, 2024 | 4 | 2024 |
BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance LJ Donoghue, MR Markovetz, CB Morrison, G Chen, KM McFadden, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 325 (6 …, 2023 | | 2023 |
193 Role of IL-1β in innate host defense of normal airway epithelia K Hasegawa, T Sadritabrizi, L Sun, R Boucher, G Chen Journal of Cystic Fibrosis 22, S100-S101, 2023 | | 2023 |
Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration Y Mikami, BR Grubb, TD Rogers, H Dang, T Asakura, P Kota, RC Gilmore, ... Science translational medicine 15 (699), eabo7728, 2023 | 12 | 2023 |
IL-1 receptor antagonist attenuates proinflammatory responses to rhinovirus in airway epithelium SA Schworer, KD Chason, G Chen, J Chen, H Zhou, AJ Burbank, ... Journal of Allergy and Clinical Immunology 151 (6), 1577-1584. e4, 2023 | 6 | 2023 |
Steroid-resistant Severe Asthma and Fatal Asthma Small Airways Are Defined by Mucus Plugging and Heterogeneous MUC5AC Expression S Schworer, K Okuda, H Dang, T Kato, G Chen, R Gilmore, M Chua, ... C19. EMERGING MECHANISMS IN COPD AND ASTHMA, A4535-A4535, 2023 | | 2023 |
Spatial transcriptional profiling of the bronchiolectatic lungs with non-cystic fibrosis bronchiectasis (NCFB) T Asakura, H Dang, K Okuda, G Chen, T Kato, Y Mikami, RC Gilmore, ... B98. THE HAPPY COUPLE: BRONCHIECTASIS AND NONTUBERCULOUS MYCOBACTERIA, A4239 …, 2023 | 1 | 2023 |
Prevalence and mechanisms of mucus accumulation in COVID-19 lung disease T Kato, T Asakura, CE Edwards, H Dang, Y Mikami, K Okuda, G Chen, ... American journal of respiratory and critical care medicine 206 (11), 1336-1352, 2022 | 36 | 2022 |
404 Why are mucins so gigantic, and is it rational to sever them to aid mucus clearance? A Livraghi-Butrico, B Grubb, J Carpenter, S Danielsen, M Markovetz, ... Journal of Cystic Fibrosis 21, S235-S236, 2022 | 1 | 2022 |
STAT3 Mutations Lead to Defective Mucociliary Clearance in the Autosomal Dominant Hyper IgE Syndrome (AD-HIES) Airways L Sun, NL Quinney, PR Sears, L Zhou, FU Dizmond, DM Cholon, ... A61. BPD, LUNG DEVELOPMENT, AND NEONATAL LUNG DISEASE, A1977-A1977, 2022 | | 2022 |
MUC5B-dominated mucus hyperproduction in the bronchiolectatic airway of non-cystic fibrosis bronchiectasis (NCFB) T Asakura, K Okuda, G Chen, T Kato, Y Mikami, GC Rodney, ... A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS, A2003 …, 2022 | 1 | 2022 |
Airway Obstruction Produces Chronic Hypoxia-Dependent Cellular Adaptation and Mucus Dehydration in Human Airway Epithelial Cells Y Mikami, B Grubb, T Rogers, H Dang, P Kota, T Asakura, J Vilar, ... A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS, A1999 …, 2022 | | 2022 |
Prevalence and mechanisms of bronchiolar mucus plugging in COVID-19 lung disease T Kato, T Asakura, CE Edwards, H Dang, Y Mikami, K Okuda, G Chen, ... B107. MOLECULAR MECHANISMS OF SARS-CoV-2, INFLUENZA, AND OTHER LUNG …, 2022 | 1 | 2022 |
Dialysis initiation in patients with chronic coronary disease and advanced chronic kidney disease in ISCHEMIA‐CKD C Briguori, RO Mathew, Z Huang, K Mavromatis, LTJ Hickson, WL Lau, ... Journal of the American Heart Association 11 (6), e022003, 2022 | 10 | 2022 |
Anakinra attenuates epithelial-derived pro-inflammatory cytokine release after rhinovirus infection S Schworer, K Chason, J Chen, H Zhou, G Chen, M Hernandez Journal of Allergy and Clinical Immunology 149 (2), AB53, 2022 | | 2022 |
357: Molecular characterization of airway in non-cystic fibrosis bronchiectasis T Asakura, K Okuda, G Chen, R Gilmore, T Kato, Y Mikami, SB Cardenas, ... Journal of Cystic Fibrosis 20, S170, 2021 | | 2021 |
515: Pathways balancing SARS-COV-2 infectivity and disease severity in CF S Nakano, K Okuda, C Edwards, H Dang, T Asakura, T Kato, Y Mikami, ... Journal of Cystic Fibrosis 20, S244, 2021 | 1 | 2021 |
Secretory cells dominate airway CFTR expression and function in human airway superficial epithelia K Okuda, H Dang, Y Kobayashi, G Carraro, S Nakano, G Chen, T Kato, ... American journal of respiratory and critical care medicine 203 (10), 1275-1289, 2021 | 142 | 2021 |