Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor S Jin, S Guo, Y Xu, X Li, C Wu, X He, B Pan, W Xin, H Zhang, W Hu, Y Yin, ... Cell Discovery 10 (1), 58, 2024 | | 2024 |
Dimerization and antidepressant recognition at noradrenaline transporter H Zhang, YL Yin, A Dai, T Zhang, C Zhang, C Wu, W Hu, X He, B Pan, ... Nature, 1-8, 2024 | | 2024 |
Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs JJ Wang, S Jin, H Zhang, Y Xu, W Hu, Y Jiang, C Chen, DW Wang, HE Xu, ... Science Advances 10 (6), eadk5184, 2024 | 2 | 2024 |
Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins Y Wang, W Liu, Y Xu, X He, Q Yuan, P Luo, W Fan, J Zhu, X Zhang, ... Nature Chemical Biology 19 (11), 1351-1360, 2023 | 13 | 2023 |
Ligand recognition and G protein coupling of the human itch receptor MRGPRX1 L Guo, Y Zhang, G Fang, L Tie, Y Zhuang, C Xue, Q Liu, M Zhang, K Zhu, ... Nature communications 14 (1), 5004, 2023 | 4 | 2023 |
GPCR activation and GRK2 assembly by a biased intracellular agonist J Duan, H Liu, F Zhao, Q Yuan, Y Ji, X Cai, X He, X Li, J Li, K Wu, T Gao, ... Nature 620 (7974), 676-681, 2023 | 27 | 2023 |
Structural genomics of the human dopamine receptor system P Xu, S Huang, BE Krumm, Y Zhuang, C Mao, Y Zhang, Y Wang, ... Cell Research 33 (8), 604-616, 2023 | 12 | 2023 |
Ligand-induced activation and G protein coupling of prostaglandin F2α receptor C Wu, Y Xu, Q He, D Li, J Duan, C Li, C You, H Chen, W Fan, Y Jiang, ... Nature Communications 14 (1), 2668, 2023 | 8 | 2023 |
Structural basis for motilin and erythromycin recognition by motilin receptor C You, Y Zhang, Y Xu, P Xu, Z Li, H Li, S Huang, Z Chen, J Li, HE Xu, ... Science Advances 9 (11), eade9020, 2023 | 3 | 2023 |
Structural basis of peptide recognition and activation of endothelin receptors Y Ji, J Duan, Q Yuan, X He, G Yang, S Zhu, K Wu, W Hu, T Gao, X Cheng, ... Nature Communications 14 (1), 1268, 2023 | 12 | 2023 |
Molecular recognition of itch-associated neuropeptides by bombesin receptors C Li, Y Xu, H Liu, H Cai, Y Jiang, HE Xu, W Yin Cell Research 33 (2), 184-187, 2023 | 3 | 2023 |
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor J Duan, P Xu, H Zhang, X Luan, J Yang, X He, C Mao, DD Shen, Y Ji, ... Nature Communications 14 (1), 519, 2023 | 15 | 2023 |
Structures of the entire human opioid receptor family Y Wang, Y Zhuang, JF DiBerto, XE Zhou, GP Schmitz, Q Yuan, MK Jain, ... Cell 186 (2), 413-427. e17, 2023 | 59 | 2023 |
Structural basis of signaling regulation of the human melanocortin-2 receptor by MRAP1 P Luo, W Feng, S Ma, A Dai, K Wu, X Chen, Q Yuan, X Cai, D Yang, ... Cell Research 33 (1), 46-54, 2023 | 10 | 2023 |
AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors X He, C You, H Jiang, Y Jiang, HE Xu, X Cheng Acta Pharmacologica Sinica 44 (1), 1-7, 2023 | 52 | 2023 |
Structures of adenosine receptor A2BR bound to endogenous and synthetic agonists H Cai, Y Xu, S Guo, X He, J Sun, X Li, C Li, W Yin, X Cheng, H Jiang, ... Cell Discovery 8 (1), 140, 2022 | 10 | 2022 |
Insights into divalent cation regulation and G13-coupling of orphan receptor GPR35 J Duan, Q Liu, Q Yuan, Y Ji, S Zhu, Y Tan, X He, Y Xu, J Shi, X Cheng, ... Cell Discovery 8 (1), 135, 2022 | 19 | 2022 |
Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19 C Wu, W Yin, Y Jiang, HE Xu Acta Pharmacologica Sinica 43 (12), 3021-3033, 2022 | 91 | 2022 |
Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein X Luan, X Li, Y Li, G Su, W Yin, Y Jiang, N Xu, F Wang, W Cheng, Y Jin, ... Science Bulletin 67 (22), 2327-2335, 2022 | 19 | 2022 |
Molecular recognition of morphine and fentanyl by the human μ-opioid receptor Cell 185 (23), 4361-4375, 2022 | 109 | 2022 |