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Kangcheng Hou
Kangcheng Hou
在 ucla.edu 的电子邮件经过验证 - 首页
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引用次数
年份
Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms
A Patowary, P Zhang, C Jops, CK Vuong, X Ge, K Hou, M Kim, N Gong, ...
Science 384 (6698), eadh7688, 2024
6*2024
Admix-kit: an integrated toolkit and pipeline for genetic analyses of admixed populations
K Hou, S Gogarten, J Kim, X Hua, JA Dias, Q Sun, Y Wang, T Tan, ...
Bioinformatics 40 (4), btae148, 2024
2024
Cell-type deconvolution of bulk-blood RNA-seq reveals biological insights into neuropsychiatric disorders
T Boltz, T Schwarz, M Bot, K Hou, C Caggiano, S Lapinska, C Duan, ...
The American Journal of Human Genetics 111 (2), 323-337, 2024
2024
Single locus theory of admixture is insufficient for the study of complex traits in admixed populations
H Lee, MH Lee, K Hou, B Pasaniuc, B Han
medRxiv, 2023.11. 07.23298201, 2023
2023
Genotype error due to low-coverage sequencing induces uncertainty in polygenic scoring
E Petter, Y Ding, K Hou, A Bhattacharya, A Gusev, N Zaitlen, B Pasaniuc
The American Journal of Human Genetics 110 (8), 1319-1329, 2023
12023
Calibrated prediction intervals for polygenic scores across diverse contexts
K Hou, Z Xu, Y Ding, A Harpak, B Pasaniuc
medRxiv, 2023
32023
Polygenic scoring accuracy varies across the genetic ancestry continuum
Y Ding, K Hou, Z Xu, A Pimplaskar, E Petter, K Boulier, F Privé, ...
Nature 618 (7966), 774-781, 2023
86*2023
Impact of cross-ancestry genetic architecture on GWASs in admixed populations
R Mester, K Hou, Y Ding, G Meeks, KS Burch, A Bhattacharya, BM Henn, ...
The American Journal of Human Genetics 110 (6), 927-939, 2023
62023
Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals
K Hou, Y Ding, Z Xu, Y Wu, A Bhattacharya, R Mester, GM Belbin, ...
Nature genetics 55 (4), 549-558, 2023
51*2023
Epigenomic and chromosomal architectural reconfiguration in developing human frontal cortex and hippocampus
MG Heffel, J Zhou, Y Zhang, DS Lee, K Hou, OP Alonso, K Abuhanna, ...
bioRxiv, 2022.10. 07.511350, 2022
42022
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
MJ Zhang, K Hou, KK Dey, S Sakaue, KA Jagadeesh, K Weinand, ...
Nature genetics 54 (10), 1572-1580, 2022
572022
Powerful eQTL mapping through low-coverage RNA sequencing
T Schwarz, T Boltz, K Hou, M Bot, C Duan, LO Loohuis, MP Boks, ...
Human Genetics and Genomics Advances 3 (3), 2022
92022
Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes
KS Burch, K Hou, Y Ding, Y Wang, S Gazal, H Shi, B Pasaniuc
The American Journal of Human Genetics 109 (4), 692-709, 2022
42022
A multi-dimensional integrative scoring framework for predicting functional variants in the human genome
X Li, G Yung, H Zhou, R Sun, Z Li, K Hou, MJ Zhang, Y Liu, T Arapoglou, ...
The American Journal of Human Genetics 109 (3), 446-456, 2022
192022
Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification
Y Ding, K Hou, KS Burch, S Lapinska, F Privé, B Vilhjálmsson, ...
Nature genetics 54 (1), 30-39, 2022
802022
On powerful GWAS in admixed populations
K Hou, A Bhattacharya, R Mester, KS Burch, B Pasaniuc
Nature genetics 53 (12), 1631-1633, 2021
172021
Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits
R Johnson, KS Burch, K Hou, M Paciuc, B Pasaniuc, S Sankararaman
PLoS computational biology 17 (10), e1009483, 2021
142021
Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization
GA Pathak, K Singh, TW Miller-Fleming, FR Wendt, N Ehsan, K Hou, ...
Nature communications 12 (1), 4569, 2021
64*2021
Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis
I Mandric, T Schwarz, A Majumdar, K Hou, L Briscoe, R Perez, ...
Nature communications 11 (1), 5504, 2020
512020
Efficient variance components analysis across millions of genomes
A Pazokitoroudi, Y Wu, KS Burch, K Hou, A Zhou, B Pasaniuc, ...
Nature communications 11 (1), 4020, 2020
57*2020
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