Design of Experiments using Box Behnken Design in the Development, Characterization, Mathematical Modeling, and Evaluation of Lung Targeted Nebulized Antiviral Camostat … R Kashikar, AK Kotha, R Shrestha, R Channappanavar, MB Chougule Journal of Drug Delivery Science and Technology, 105810, 2024 | | 2024 |
The use of human iPSC‐derived alveolar organoids to explore SARS‐CoV‐2 variant infections and host responses C Gandikota, K Vaddadi, P Sivasami, C Huang, Y Liang, S Pushparaj, ... Journal of Medical Virology 96 (4), e29579, 2024 | | 2024 |
Acellular Human Amniotic Fluid-Derived Extracellular Vesicles as Novel Anti-Inflammatory Therapeutics against SARS-CoV-2 Infection D Chanda, T Del Rivero, R Ghimire, S More, MI Mitrani, MA Bellio, ... Viruses 16 (2), 273, 2024 | 1 | 2024 |
Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection CM Kerr, JJ Pfannenstiel, YM Alhammad, A Roy, JJ O’Connor, R Ghimire, ... bioRxiv, 2024 | 1 | 2024 |
Differential TLR-ERK1/2 activity promotes viral ssRNA and dsRNA mimic-induced dysregulated immunity in macrophages R Shrestha, P Johnson, R Ghimire, C Whitley, R Channappanavar bioRxiv, 2024.05. 24.595760, 2024 | | 2024 |
SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice YM Alhammad, S Parthasarathy, R Ghimire, CM Kerr, JJ O’Connor, ... Proceedings of the National Academy of Sciences 120 (35), e2302083120, 2023 | 19 | 2023 |
Toll-like receptor 7 (TLR7)-mediated antiviral response protects mice from lethal SARS-CoV-2 infection R Ghimire, R Shrestha, R Amaradhi, T Patton, C Whitley, D Chanda, L Liu, ... bioRxiv, 2023.05. 08.539929, 2023 | | 2023 |
Differential role of TLR7 signaling in SARS-CoV-2-induced antiviral and inflammatory responses R Ghimire, T Patton, R Shrestha, D Chanda, S More, R Channappanavar The Journal of Immunology 210 (1_Supplement), 72.17-72.17, 2023 | | 2023 |
Dysregulated myeloid cell activity is associated with fatal disease in SARS-CoV-2 infected aged mice D Chanda, R Ghimire, R Channappanavar, M Mack The Journal of Immunology 210 (1_Supplement), 71.31-71.31, 2023 | | 2023 |
Amniotic fluid derived extracellular vesicles as novel anti-inflammatory therapeutics against SARS-CoV-2 infection D Chanda, MA Bellio, T del Rivero, MI Mitrani, R Channappanavar The Journal of Immunology 210 (1_Supplement), 235.15-235.15, 2023 | | 2023 |
Klebsiella pneumoniae Co-infection Leads to Fatal Pneumonia in SARS-CoV-2-infected Mice C Villalva, G Patil, S Narayanan, D Chanda, R Ghimire, T Snider, ... bioRxiv, 2023.07. 28.551035, 2023 | 1 | 2023 |
Toll-like receptor 7 (TLR7)-mediated antiviral response protects mice from lethal SARS-CoV-2 infection (preprint) R Ghimire, R Shrestha, R Amaradhi, T Patton, C Whitley, D Chanda, L Liu, ... | | 2023 |
SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice (preprint) YM Alhammad, S Parthasarathy, R Ghimire, CM Kerr, JJ Pfannenstiel, ... | | 2023 |
Alveolar macrophages protect mice from MERS-CoV-induced pneumonia and severe disease R Channappanavar, M Selvaraj, S More, S Perlman Veterinary pathology 59 (4), 627-638, 2022 | 5 | 2022 |
Effective interferon lambda treatment regimen to control lethal MERS-CoV infection in mice R Dijkman, AK Verma, M Selvaraj, R Ghimire, HH Gad, R Hartmann, ... Journal of virology 96 (11), e00364-22, 2022 | 8 | 2022 |
Time-dependent increase in susceptibility and severity of secondary bacterial infections during SARS-CoV-2 AP Smith, EP Williams, TR Plunkett, M Selvaraj, LC Lane, L Zalduondo, ... Frontiers in Immunology 13, 894534, 2022 | 14 | 2022 |
Interferons in coronavirus pathogenesis: The good, the bad, and the ugly R Channappanavar Cell Host & Microbe 30 (4), 427-430, 2022 | 4 | 2022 |
Time-Dependent Increase in Susceptibility and Severity of Secondary Bacterial Infection during SARS-CoV-2 Infection (preprint) AP Smith, E Williams, T Plunkett, M Selvaraj, L Lane, L Zalduondo, Y Xue, ... | | 2022 |
IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1–Induced Corneal Immunopathology F Antony, C Pundkar, M Sandey, AK Jaiswal, A Mishra, A Kumar, ... The Journal of Immunology 206 (8), 1866-1877, 2021 | 19 | 2021 |
Effective interferon (IFN)-lambda treatment regimen to control lethal MERS-CoV infection in mice (preprint) R Dijkman, M Selvaraj, HH Gad, S More, R Hartmann, S Perlman, V Thiel, ... | | 2021 |