Uncovering the biotechnological capacity of marine and brackish water Planctomycetota IR Vitorino, E Pinto, J Martín, TA Mackenzie, MC Ramos, P Sánchez, ... Antonie van Leeuwenhoek 117 (1), 26, 2024 | 2 | 2024 |
Onychocolone A produced by the fungus Onychocola sp. targets cancer stem cells and stops pancreatic cancer progression by inhibiting MEK2-dependent cell signaling MC Ramos, G Crespo-Sueiro, N de Pedro, C Griñán-Lisón, C Díaz, ... Biomedicine & Pharmacotherapy 177, 117018, 2024 | | 2024 |
Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals F Castillo, D Ramírez, MC Ramos, B Martinez-Arribas, ... Frontiers in Pharmacology 15, 1390705, 2024 | | 2024 |
Acoustic droplet ejection facilitates cell-based high-throughput screenings using natural products TA Mackenzie, JR Tormo, B Cautain, G Martínez, I Sánchez, O Genilloud, ... SLAS technology 29 (3), 100111, 2024 | 1 | 2024 |
Assessment of Untargeted Metabolomics by Hydrophilic Interaction Liquid Chromatography− Mass Spectrometry to Define Breast Cancer Liquid Biopsy-Based Biomarkers in Plasma Samples C González Olmedo, L Díaz Beltrán, V Madrid García, JL Palacios Ferrer, ... International Journal of Molecular Sciences 25 (10), 5098, 2024 | | 2024 |
Identification of novel biomarkers in the early diagnosis of malignant melanoma by untargeted liquid chromatography coupled to high-resolution mass spectrometry-based … J Peña-Martín, M Belén García-Ortega, JL Palacios-Ferrer, C Díaz, ... British Journal of Dermatology 190 (5), 740-750, 2024 | | 2024 |
A yeast-based high-throughput screen identifies inhibitors of trypanosomatid HRG heme transporters with potent leishmanicidal and trypanocidal activity M Cabello-Donayre, I Cabello-Donayre, D Guerra, LM Orrego, ... International Journal of Antimicrobial Agents 63 (3), 107092, 2024 | | 2024 |
New Antifungal Drugs: Discovery and Therapeutic Potential F Vicente, F Reyes, O Genilloud Fungi Bioactive Metabolites: Integration of Pharmaceutical Applications, 371-400, 2024 | | 2024 |
Unveiling the bioactive potential of Actinomycetota from the Tagus River estuary JDN Dos Santos, E Pinto, J Martín, F Vicente, F Reyes, OM Lage International Microbiology, 1-16, 2024 | | 2024 |
Identification of novel biomarkers for early diagnosis of malignant melanoma by untargeted LC-HRMS-based metabolomics: a pilot study J Peña-Martín, MB García-Ortega, JL Palacios-Ferrer, C Díaz, ... British Journal of Dermatology, 2024 | 1 | 2024 |
Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity B Martínez-Arribas, F Annang, R Díaz-González, G Pérez-Moreno, ... Microbiology Spectrum 12 (1), e01679-23, 2024 | 1 | 2024 |
Anti-infectives screening at the IPBLN: discovery of antiviral microbial natural products B Martínez-Arribas, D González-Pacanowska, F Reyes, F Vicente, ... | | 2023 |
Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi C Bosch-Navarrete, G Pérez-Moreno, F Annang, R Diaz-Gonzalez, ... PLOS Neglected Tropical Diseases 17 (9), e0011592, 2023 | 3 | 2023 |
New Phocoenamicin and Maklamicin Analogues from Cultures of Three Marine-Derived Micromonospora Strains M Kokkini, D Oves-Costales, P Sánchez, Á Melguizo, TA Mackenzie, ... Marine Drugs 21 (8), 443, 2023 | 1 | 2023 |
Pepper fruit extracts show anti-proliferative activity against tumor cells altering their NADPH-generating dehydrogenase and catalase profiles M Rodríguez-Ruiz, MC Ramos, MJ Campos, I Díaz-Sánchez, B Cautain, ... Antioxidants 12 (7), 1461, 2023 | 3 | 2023 |
The anti-proliferative activity of pepper fruits against tumor cells is possibly linked to the impairment of the NADPH and H2O2 metabolisms M Rodríguez-Ruiz, C Ramos, MJ Campos, F Vicente, FJ Corpas, ... Free Radical Biology and Medicine 201, 61, 2023 | | 2023 |
New dual inhibitors of bacterial topoisomerases with broad-spectrum antibacterial activity and in vivo efficacy against vancomycin-intermediate Staphylococcus aureus M Durcik, AE Cotman, Z Toplak, S Mozina, Z Skok, PE Szili, M Czikkely, ... Journal of medicinal chemistry 66 (6), 3968-3994, 2023 | 9 | 2023 |
Antiparasitic Meroterpenoids Isolated from Memnoniella dichroa CF-080171 FB Annang, G Pérez-Moreno, C Bosch-Navarrete, V González-Menéndez, ... Pharmaceutics 15 (2), 492, 2023 | | 2023 |
Discovery and hit-to-lead optimization of benzothiazole scaffold-based DNA gyrase inhibitors with potent activity against Acinetobacter baumannii and Pseudomonas aeruginosa AE Cotman, M Durcik, D Benedetto Tiz, F Fulgheri, D Secci, M Sterle, ... Journal of medicinal chemistry 66 (2), 1380-1425, 2023 | 14 | 2023 |
Pepper fruit, as a nutraceutical food, shows antiproliferative activity against tumor cells and it is potentiatied by nitric oxide (NO) JM Palma, JP del Palacio, M Rodríguez-Ruiz, S González-Gordo, C Díaz, ... Nitric Oxide in Health and Disease, 193-210, 2023 | 3 | 2023 |