Abstract LB039: VHL-deficient renal cell carcinoma displays defective ATM activation and sensitivity to ATR inhibition PG Pilie, L Zhou, YT Zhang, C Peterson, D McGrail, Y Peng, G Peng, ... Cancer Research 82 (12_Supplement), LB039-LB039, 2022 | | 2022 |
PBRM1 loss promotes resistance to immunotherapy in RCC. XD Liu, W Kong, A Hoang, X Zhang, L Zhou, PG Pilie, S Isgandrova, ... CANCER IMMUNOLOGY RESEARCH 8 (4), 105-105, 2020 | | 2020 |
Abstract B48: PBRM1 loss promotes resistance to immunotherapy in RCC XD Liu, W Kong, A Hoang, X Zhang, L Zhou, PG Pilie, S Isgandrova, ... Cancer Immunology Research 8 (4_Supplement), B48-B48, 2020 | | 2020 |
PBRM1 loss reduces IFNγ-STAT1 activity and promotes resistance to immunotherapy and antiangiogenic therapy in renal cell carcinoma X Liu, W Kong, C Peterson, A Hoang, X Zhang, L Zhou, P Pilie, T Lam, ... Cancer Research 79 (13_Supplement), 945-945, 2019 | 1 | 2019 |
Tip60 dependent DNA homologous recombination repair is impaired in VHL-deficient clear cell renal cell carcinoma L Zhou, PG Pilie, CB Peterson, X Liu, X Zhang, E Jonasch Cancer Research 78 (13_Supplement), 1364-1364, 2018 | 2 | 2018 |
Functional biomarkers of homologous repair (HR) deficiency to guide novel DNA damage response targeted therapy in clear cell renal cell carcinoma (ccRCC). PG Pilie, CB Peterson, Y Peng, L Zhou, TA Yap, G Peng, E Jonasch Journal of Clinical Oncology 36 (15_suppl), 4576-4576, 2018 | 2 | 2018 |
Homologous repair deficiency in VHL-mutated clear cell renal cell carcinoma. PG Pilie, L Zhou, CB Peterson, Y Peng, G Peng, E Jonasch Journal of Clinical Oncology 36 (6_suppl), 585-585, 2018 | 4 | 2018 |
HNF1B loss exacerbates the development of chromophobe renal cell carcinomas M Sun, P Tong, W Kong, B Dong, Y Huang, IY Park, L Zhou, XD Liu, ... Cancer research 77 (19), 5313-5326, 2017 | 28 | 2017 |
The role of hepatocyte nuclear factor 1 homeobox B (HNF1B) loss in chromophobe RCC (ChRCC) development E Jonasch, G Fuller, I McCutcheon, Z Ding, L Zhou, X Liu, W Kong, ... Annals of Oncology 28, v602, 2017 | | 2017 |
Genomic instability and DNA damage repair in clear cell renal cell carcinoma. PG Pilie, L Zhou, P Tong, SF Matin, K Sircar, P Tamboli, JA Karam, ... Journal of Clinical Oncology 35 (15_suppl), 4581-4581, 2017 | 2 | 2017 |
Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function P German, S Bai, XD Liu, M Sun, L Zhou, S Kalra, X Zhang, R Minelli, ... Oncogene 35 (38), 4973-4980, 2016 | 13 | 2016 |
Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma L Zhou, XD Liu, M Sun, X Zhang, P German, S Bai, Z Ding, N Tannir, ... Oncogene 35 (21), 2687-2697, 2016 | 404 | 2016 |
Loss of p27 associated with risk for endometrial carcinoma arising in the setting of obesity AS McCampbell, ML Mittelstadt, R Dere, S Kim, L Zhou, B Djordjevic, ... Current molecular medicine 16 (3), 252-265, 2016 | 10 | 2016 |
Sunitinib to upregulate IFNg-STAT1 signaling and to increase indoleamine 2, 3-dioxygenase (IDO) expression in renal cell carcinoma (RCC). E Jonasch, A Hoang, M Sun, L Zhou, Z Ding, X Zhang, S Bai, NM Tannir, ... Journal of Clinical Oncology 34 (2_suppl), 614-614, 2016 | 5 | 2016 |
Resistance to antiangiogenic therapy is associated with an immunosuppressive tumor microenvironment in metastatic renal cell carcinoma XD Liu, A Hoang, L Zhou, S Kalra, A Yetil, M Sun, Z Ding, X Zhang, S Bai, ... Cancer immunology research 3 (9), 1017-1029, 2015 | 197 | 2015 |
Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis XD Liu, J Yao, DN Tripathi, Z Ding, Y Xu, M Sun, J Zhang, S Bai, ... Oncogene 34 (19), 2450-2460, 2015 | 85 | 2015 |
p27 as a biomarker and determinant of risk for endometrial carcinoma arising in the setting of obesity AS McCampbell, ML Mittlestedt, R Dere, L Zhou, B Djordjevic, PT Soliman, ... Cancer Research 74 (19_Supplement), 4102-4102, 2014 | 1 | 2014 |
Anti-Angiogenic Therapy Induces T-Lymphocyte Infiltration Associated with Poor Survival in Metastatic Renal Cell Carcinoma Patients X Liu, A Hoang, L Zhou, S Kalra, M Sun, Z Ding, S Bai, P German, ... Annals of Oncology 25, iv365, 2014 | | 2014 |
Induced CD4 Positive T-lymphocyte infiltration predicts poor survival in metastatic renal cell carcinoma patients treated with antiangiogenic therapy XD Liu, A Hoang, L Zhou, S Kalra, M Sun, Z Ding, S Bai, P German, ... ANGIOGENESIS 17 (3), 744-744, 2014 | | 2014 |
Genetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein Z Ding, P German, S Bai, AS Reddy, XD Liu, M Sun, L Zhou, X Chen, ... Cancer research 74 (11), 3127-3136, 2014 | 27 | 2014 |