Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles P Zhang, S Falcone, Y Tsybovsky, M Singh, V Gopan, H Miao, Y Seo, ... Proceedings of the National Academy of Sciences 120 (29), e2305896120, 2023 | 3 | 2023 |
Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters X Liu, HS Park, Y Matsuoka, C Santos, L Yang, C Luongo, IN Moore, ... PLoS Pathogens 19 (6), e1011057, 2023 | 3 | 2023 |
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys C Le Nouën, CE Nelson, X Liu, HS Park, Y Matsuoka, C Luongo, ... Cell 185 (25), 4811-4825. e17, 2022 | 27* | 2022 |
Anti-PF4 antibodies associated with disease severity in COVID-19 Q Liu, H Miao, S Li, P Zhang, GF Gerber, D Follmann, H Ji, SL Zeger, ... Proceedings of the National Academy of Sciences 119 (47), e2213361119, 2022 | 19 | 2022 |
Potent Monoclonal antibodies neutralize Omicron Sublineages and other SARS-Cov-2 variants Z Chen, P Zhang, Y Matsuoka, Y Tsybovsky, K West, C Santos, LF Boyd, ... Cell Reports 41 (5), 2022 | 6 | 2022 |
Hiv rna vaccines P Lusso, P Zhang, E Narayanan, SM Elbashir US Patent App. 17/439,198, 2022 | 12 | 2022 |
Optimization of a VLP-forming HIV-1 env-gagmRNA vaccine by inclusion of gag-pol mRNA to express the viral protease P Zhang, S Falcone, G Stewart-Jones, Y Seo, D Rogers, H Miao, Q Liu, ... JOURNAL OF THE INTERNATIONAL AIDS SOCIETY 25, 3-3, 2022 | | 2022 |
Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants Z Chen, P Zhang, Y Matsuoka, Y Tsybovsky, K West, C Santos, LF Boyd, ... MedRxiv, 2022.01. 12.22269023, 2022 | 16 | 2022 |
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Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques (preprint) C Le Nouën, C Nelson, X Liu, HS Park, Y Matsuoka, C Luongo, C Santos, ... | | 2022 |
A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques P Zhang, E Narayanan, Q Liu, Y Tsybovsky, K Boswell, S Ding, Z Hu, ... Nature medicine 27 (12), 2234-2245, 2021 | 99 | 2021 |
Quaternary interaction of the HIV-1 envelope trimer with CD4 and neutralizing antibodies Q Liu, P Zhang, P Lusso Viruses 13 (7), 1405, 2021 | 7 | 2021 |
Rational engraftment of quaternary-interactive acidic loops for anti-HIV-1 antibody improvement Q Liu, P Zhang, H Miao, Y Lin, YD Kwon, PD Kwong, ... Journal of Virology 95 (12), 10.1128/jvi. 00159-21, 2021 | 4 | 2021 |
Functional anatomy of the trimer apex reveals key hydrophobic constraints that maintain the HIV-1 envelope spike in a closed state P Zhang, AL Kwon, C Guzzo, Q Liu, H Schmeisser, H Miao, Y Lin, ... Mbio 12 (2), 10.1128/mbio. 00090-21, 2021 | 10 | 2021 |
Recombinant HIV-1 envelope proteins and their use P Lusso, P Zhang US Patent 10,808,011, 2020 | | 2020 |
LATE BREAKING ABSTRACTS P Zhang, M Prabhakaran, S Ding, Y Tsybovsky, E Narayanan, A Carfi, ... Oral Abstracts from the 23rd International AIDS Conference 6-10 July 2020, 168, 2020 | | 2020 |
Induction of cross-neutralizing antibodies and protection from heterologous tier-2 SHIV challenge by an mRNA-based vaccine in macaques P Zhang, M Prabhakaran, S Ding, Y Tsybovsky, E Narayanan, A Carfi, ... JOURNAL OF THE INTERNATIONAL AIDS SOCIETY 23, 168-168, 2020 | 1 | 2020 |
HIV vaccine delayed boosting increases Env variable region 2–specific antibody effector functions D Easterhoff, J Pollara, K Luo, B Janus, N Gohain, LTD Williams, MZ Tay, ... JCI insight 5 (2), 2020 | 24 | 2020 |
Improvement of antibody functionality by structure-guided paratope engraftment Q Liu, YT Lai, P Zhang, MK Louder, A Pegu, R Rawi, M Asokan, X Chen, ... Nature Communications 10 (1), 721, 2019 | 31 | 2019 |
Structural constraints at the trimer apex stabilize the HIV-1 envelope in a closed, antibody-protected conformation C Guzzo, P Zhang, Q Liu, AL Kwon, F Uddin, AI Wells, H Schmeisser, ... Mbio 9 (6), 10.1128/mbio. 00955-18, 2018 | 15 | 2018 |