关注
Jason F. Kreisberg, Ph.D.
Jason F. Kreisberg, Ph.D.
Sanford Laboratories for Innovative Medicines
在 sanfordlabs.org 的电子邮件经过验证
标题
引用次数
年份
De novo generation of multi-target compounds using deep generative chemistry
BP Munson, M Chen, A Bogosian, JF Kreisberg, K Licon, R Abagyan, ...
Nature Communications 15 (1), 3636, 2024
22024
Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks
SN Wright, BS Leger, SB Rosenthal, SN Liu, T Jia, AS Chitre, ...
Cell reports 42 (8), 2023
52023
Mapping the common gene networks that underlie related diseases
SB Rosenthal, SN Wright, S Liu, C Churas, D Chilin-Fuentes, CH Chen, ...
Nature protocols 18 (6), 1745-1759, 2023
52023
Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation
K Ford, BP Munson, SH Fong, R Panwala, WK Chu, J Rainaldi, ...
Scientific reports 13 (1), 7678, 2023
12023
Predicting clinical drug responses using a few-shot learning-based interpretable AI
S Park, A Singhal, E Silva, JF Kreisberg, T Ideker
Cancer Research 82 (12_Supplement), 1159-1159, 2022
2022
Prediction of therapeutic response via data-driven maps of tumor cell architecture
EN Silva, A Singhal, S Park, J Kreisberg, T Ideker
Cancer Research 82 (12_Supplement), 636-636, 2022
2022
A multi-scale map of cell structure fusing protein images and interactions
Y Qin, EL Huttlin, CF Winsnes, ML Gosztyla, L Wacheul, MR Kelly, ...
Nature 600 (7889), 536-542, 2021
562021
Interpretation of cancer mutations using a multiscale map of protein systems
F Zheng, MR Kelly, DJ Ramms, ML Heintschel, K Tao, B Tutuncuoglu, ...
Science 374 (6563), eabf3067, 2021
402021
A protein interaction landscape of breast cancer
M Kim, J Park, M Bouhaddou, K Kim, A Rojc, M Modak, M Soucheray, ...
Science 374 (6563), eabf3066, 2021
912021
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity
DL Swaney, DJ Ramms, Z Wang, J Park, Y Goto, M Soucheray, N Bhola, ...
Science 374 (6563), eabf2911, 2021
432021
Genetic dissection of complex traits using hierarchical biological knowledge
H Tanaka, JF Kreisberg, T Ideker
PLoS Computational Biology 17 (9), e1009373, 2021
22021
Mutations in iron-sulfur cluster proteins are associated with decreased bladder cancer cell senescence and improved survival outcomes
D Patel, F Zheng, M Chen, J Kreisberg, E Silva, T Ideker, K Licon
Cancer Research 81 (13_Supplement), 217-217, 2021
2021
Systematic mapping of genetic interactions in human cancer cells reveals context dependent cancer signaling pathways
SH Fong, BM Kuenzi, J Lee, K Sanchez, A Bojorquez-Gomez, K Ford, ...
Cancer Research 81 (13_Supplement), 2133-2133, 2021
2021
Predicting drug response and synergy using a deep learning model of human cancer cells
BM Kuenzi, J Park, SH Fong, KS Sanchez, J Lee, JF Kreisberg, J Ma, ...
Cancer cell 38 (5), 672-684. e6, 2020
3102020
Quantitative translation of dog-to-human aging by conserved remodeling of the DNA methylome
T Wang, J Ma, AN Hogan, S Fong, K Licon, B Tsui, JF Kreisberg, ...
Cell systems 11 (2), 176-185. e6, 2020
902020
DrugCell: A visible neural network to guide personalized medicine
BM Kuenzi, J Park, S Fong, K Sanchez, J Kreisberg, J Ma, T Ideker
Cancer Research 80 (16_Supplement), 1925-1925, 2020
2020
Using physical, genetic and integrated cancer cell maps to investigate head and neck cancer and breast cancer
JF Kreisberg, F Zheng, S Fong, BM Kuenzi, K Ford, D Swaney, M Kim, ...
Cancer Research 80 (16_Supplement), 223-223, 2020
2020
Mapping cell structure across scales by fusing protein images and interactions
Y Qin, CF Winsnes, EL Huttlin, F Zheng, W Ouyang, J Park, A Pitea, ...
bioRxiv, 2020.06. 21.163709, 2020
62020
Prospecting whole cancer genomes
JF Kreisberg, T Ideker, F Meric-Bernstam, G Mills
Nature Cancer 1 (3), 273-275, 2020
2020
Abstract C006: DrugCell: A visible neural network to guide precision medicine
BM Kuenzi, J Park, S Fong, J Kreisberg, T Ideker
Molecular Cancer Therapeutics 18 (12_Supplement), C006-C006, 2019
2019
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