Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model S Abudahab, MM Kronfol, MG Dozmorov, T Campbell, FM Jahr, J Nguyen, ... GeroScience, 1-14, 2024 | | 2024 |
Ketamine Produces Antidepressant Effects by Inhibiting Histone Deacetylases and Upregulating Hippocampal Brain-Derived Neurotrophic Factor Levels in a Diisopropyl … A Ribeiro-Davis, DY Al Saeedy, FM Jahr, E Hawkins, JL McClay, ... Journal of Pharmacology and Experimental Therapeutics 388 (2), 647-654, 2024 | 4 | 2024 |
Epigenetic regulation of drug metabolism in aging: utilizing epigenetics to optimize geriatric pharmacotherapy S Abudahab, PW Slattum, ET Price, JL McClay Pharmacogenomics 25 (1), 41-54, 2024 | | 2024 |
The aryl hydrocarbon receptor, epigenetics and the aging process S Abudahab, ET Price, MG Dozmorov, LS Deshpande, JL McClay The Journal of nutrition, health and aging 27 (4), 291-300, 2023 | 3 | 2023 |
Epigenetics in drug disposition & drug therapy: symposium report of the 24th North American meeting of the International Society for the Study of Xenobiotics (ISSX) BJ Maldonato, AG Vergara, J Yadav, SM Glass, EM Paragas, D Li, ... Drug metabolism reviews 54 (3), 318-330, 2022 | 3 | 2022 |
Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats ACR Ribeiro, E Hawkins, FM Jahr, JL McClay, LS Deshpande Neurotoxicology 90, 172-183, 2022 | 9 | 2022 |
Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal aging MM Kronfol, S Abudahab, MG Dozmorov, FM Jahr, MS Halquist, ... Pharmacogenetics and genomics 31 (9), 207-214, 2021 | 7 | 2021 |
Epigenetic histone acetylation and Bdnf dysregulation in the hippocampus of rats exposed to repeated, low-dose diisopropylfluorophosphate ACR Ribeiro, FM Jahr, E Hawkins, MM Kronfol, RM Younis, JL McClay, ... Life sciences 281, 119765, 2021 | 11 | 2021 |
Epigenetic regulation of drug metabolism in aging JL McClay Aging (Albany NY) 13 (13), 16898, 2021 | 1 | 2021 |
Review and consensus on pharmacogenomic testing in psychiatry CA Bousman, SA Bengesser, KJ Aitchison, AT Amare, H Aschauer, ... Pharmacopsychiatry 54 (01), 5-17, 2021 | 139 | 2021 |
Molecular mechanisms for the antidepressant-like effects of a low-dose ketamine treatment in a DFP-based rat model for Gulf War Illness ACR Ribeiro, J Zhu, MM Kronfol, FM Jahr, RM Younis, E Hawkins, ... Neurotoxicology 80, 52-59, 2020 | 26 | 2020 |
DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver MM Kronfol, FM Jahr, MG Dozmorov, PS Phansalkar, LY Xie, KA Aberg, ... Geroscience 42, 819-832, 2020 | 29 | 2020 |
Cell-type specific differences in antiretroviral penetration and the effects of HIV-1 Tat and morphine among primary human brain endothelial cells, astrocytes, pericytes, and … SH Patel, OA Ismaiel, WR Mylott Jr, M Yuan, JL McClay, JJ Paris, ... Neuroscience letters 712, 134475, 2019 | 19 | 2019 |
The ANKS1B gene and its associated phenotypes: focus on CNS drug response RM Younis, RM Taylor, PM Beardsley, JL McClay Pharmacogenomics 20 (9), 669-684, 2019 | 16 | 2019 |
Epigenetic biomarkers in personalized medicine MM Kronfol, JL McClay Prognostic Epigenetics, 375-395, 2019 | 6 | 2019 |
Building a schizophrenia genetic network: transcription factor 4 regulates genes involved in neuronal development and schizophrenia risk H Xia, FM Jahr, NK Kim, L Xie, AA Shabalin, J Bryois, DH Sweet, ... Human Molecular Genetics 27 (18), 3246-3256, 2018 | 35 | 2018 |
Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function In Vitro S Patel, CR Leibrand, P Palasuberniam, PO Couraud, B Weksler, FM Jahr, ... Antimicrobial agents and chemotherapy 61 (12), 10.1128/aac. 01307-17, 2017 | 27 | 2017 |
Metabolomics-based biomarkers for lung function JL Mcclay, BK Zedler, EL Murrelle, EJCG Van Den Oord, T O'connell, ... US Patent 9,823,204, 2017 | 4 | 2017 |
Building a schizophrenia genetic network: Evidence that Transcription Factor 4 regulates schizophrenia risk genes H Xia, FM Jahr, NK Kim, L Xie, AA Shabalin, J Bryois, DH Sweet, ... bioRxiv, 215715, 2017 | | 2017 |
Deep sequencing of 71 candidate genes to characterize variation associated with alcohol dependence SL Clark, JL McClay, DE Adkins, G Kumar, KA Aberg, S Nerella, L Xie, ... Alcoholism: Clinical and Experimental Research 41 (4), 711-718, 2017 | 10 | 2017 |