A mechanism of IL-34-induced resistance against cytotoxic anti-cancer therapies such as radiation by X-ray and chemotherapy by Oxaliplatin N Han, H Wada, T Kobayashi, R Otsuka, KI Seino OncoImmunology 12 (1), 2238499, 2023 | | 2023 |
Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cells N Kajihara, Y Tanaka, R Takeuchi, T Kobayashi, M Tanji, T Ataka, ... OncoImmunology 12 (1), 2213132, 2023 | | 2023 |
Blocking of oestrogen signals improves anti-tumour effect regardless of oestrogen receptor alpha expression in cancer cells N Kajihara, Y Ge, K Seino British Journal of Cancer 129 (6), 935-946, 2023 | 4 | 2023 |
Induced pluripotent stem cell–derived hematopoietic stem and progenitor cells induce mixed chimerism and donor-specific allograft tolerance T Murata, N Hama, T Kamatani, A Mori, R Otsuka, H Wada, K Seino American Journal of Transplantation 23 (9), 1331-1344, 2023 | | 2023 |
Induction of allograft tolerance by adoptive transfer of donor B cells: an immune regulatory strategy for transplantation using MHC-matched iPS cells T Murata, R Otsuka, A Sasaki, T Kamatani, H Wada, H Yamakawa, ... International Immunology 35 (7), 327-338, 2023 | | 2023 |
iPSC-derived hematopoietic stem and progenitor cells induce mixed chimerism and donor-specific allograft tolerance. T Murata, N Hama, T Kamatani, A Mori, R Otsuka, H Wada, KI Seino American Journal of Transplantation: Official Journal of the American …, 2023 | | 2023 |
Interleukin-34 cancels anti-tumor immunity by PARP inhibitor T Nakamura, N Kajihara, N Hama, T Kobayashi, R Otsuka, N Han, ... Journal of Gynecologic Oncology 34 (3), 2023 | 1 | 2023 |
Tumor-derived interleukin-34 creates an immunosuppressive and chemoresistant tumor microenvironment by modulating myeloid-derived suppressor cells in triple-negative breast cancer N Kajihara, T Kobayashi, R Otsuka, J Nio-Kobayashi, T Oshino, ... Cancer Immunology, Immunotherapy 72 (4), 851-864, 2023 | 9 | 2023 |
Tumor cell-induced macrophage senescence plays a pivotal role in tumor initiation followed by stable growth in immunocompetent condition H Wada, R Otsuka, WTV Germeraad, T Murata, T Kondo, K Seino Journal for Immunotherapy of Cancer 11 (11), 2023 | 1 | 2023 |
Studies on immune regulation for allogeneic iPSC-based transplantation K Seino Inflammation and Regeneration 42 (1), 65, 2022 | | 2022 |
Tumour cell-induced senescence-like state of macrophages plays a pivotal role in tumour stable growth after tumour cell emergence in immunocompetent condition H Wada, R Otsuka, W Germeraad, T Murata, T Kondo, K Seino | | 2022 |
Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model T Kamatani, R Otsuka, T Murata, H Wada, T Takahashi, A Mori, S Murata, ... Inflammation and Regeneration 42 (1), 4, 2022 | 6 | 2022 |
Interleukin-34; A Key Molecule Responsible for Poor Prognosis of Triple-Negative Breast Cancer N Kajihara, K Seino CANCER SCIENCE 113, 1025-1025, 2022 | | 2022 |
Macrophage-like iPS-derived Suppressor Cells Reduce Th1-mediated Immune Response to a Retinal Antigen K Hase, K Namba, H Wada, H Tsuji, A Maeda, T Murata, R Otsuka, ... Current eye research 46 (12), 1908-1916, 2021 | | 2021 |
Treatment-resistance reducing agent for treatment-resistant cancer M BAGHDADI, KI Seino | | 2021 |
An optimized protocol for patient-derived xenograft in humanized mice to evaluate the role of IL-34 in immunotherapeutic resistance N Han, HY Jang, N Hama, T Kobayashi, R Otsuka, H Wada, K Seino STAR protocols 2 (2), 100460, 2021 | 5 | 2021 |
Efficient generation of thymic epithelium from induced pluripotent stem cells that prolongs allograft survival (vol 10, 224, 2020) R Otsuka, H Wada, H Tsuji, A Sasaki, T Murata, M Itoh, M Baghdadi, ... SCIENTIFIC REPORTS 11 (1), 2021 | | 2021 |
IL-34, the rationale for its expression in physiological and pathological conditions R Otsuka, H Wada, K Seino Seminars in Immunology 54, 101517, 2021 | 13 | 2021 |
Establishment of human leukocyte antigen-mismatched immune responses after transplantation of human liver bud in humanized mouse models A Mori, S Murata, N Tashiro, T Tadokoro, S Okamoto, R Otsuka, H Wada, ... Cells 10 (2), 476, 2021 | 11 | 2021 |
Tumor-initiation via macrophage senescence H Wada, T Kondo, K Seino CANCER SCIENCE 112, 416-416, 2021 | | 2021 |