Systems biology study of Huntington's disease LE Dionisio, P Langfelder, JS Aaronson, J Rosinski, XW Yang Huntington's Disease, 353-396, 2024 | | 2024 |
Accelerated aging with HIV begins at the time of initial HIV infection EC Breen, ME Sehl, R Shih, P Langfelder, R Wang, S Horvath, JH Bream, ... Iscience 26 (8), 2023 | 1 | 2023 |
Erratum: Accelerated aging with HIV begins at the time of initial HIV infection. R Wang, S Horvath, J Bream, P Duggal, J Martinson, S Wolinsky, ... iScience 26 (8), 2023 | | 2023 |
Package ‘matrixStats’ H Bengtsson, HC Bravo, MH Bengtsson, T LazyLoad, T ByteCompile, ... | 6 | 2023 |
BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice CYD Lee, AJ De La Rocha, K Inouye, P Langfelder, A Daggett, X Gu, ... bioRxiv, 2023.08. 03.551881, 2023 | | 2023 |
Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures N Wang, P Langfelder, M Stricos, L Ramanathan, JB Richman, R Vaca, ... Neuron 110 (20), 3318-3338. e9, 2022 | 7 | 2022 |
Accelerated aging with HIV begins at the time of initial HIV infection EC Breen, ME Sehl, R Shih, P Langfelder, R Wang, S Horvath, JH Bream, ... IScience 25 (7), 2022 | 23 | 2022 |
Bone marrow haematopoietic stem cells influence liver homeostatic networks and cancer development after dietary intervention G Alipour Talash, P Langfelder, D Vitale, M Karimi Azardaryany, ... bioRxiv, 2022.04. 16.488543, 2022 | | 2022 |
Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice X Gu, J Richman, P Langfelder, N Wang, S Zhang, M Bañez-Coronel, ... Neuron 110 (7), 1173-1192. e7, 2022 | 28 | 2022 |
Core liver homeostatic co-expression networks are preserved but respond to perturbations in an organism-and disease-specific manner S Esmaili, P Langfelder, TG Belgard, D Vitale, MK Azardaryany, ... Cell Systems 12 (5), 432-445. e7, 2021 | 18 | 2021 |
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s disease EL Morozko, C Smith-Geater, AM Monteys, S Pradhan, RG Lim, ... Proceedings of the National Academy of Sciences 118 (4), e2021836118, 2021 | 31 | 2021 |
Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington’s disease patients CYD Lee, N Wang, K Shen, M Stricos, P Langfelder, KH Cheon, ... Scientific reports 10 (1), 20295, 2020 | 14 | 2020 |
Brainwide genetic sparse cell labeling to illuminate the morphology of neurons and glia with cre-dependent MORF mice MB Veldman, CS Park, CM Eyermann, JY Zhang, E Zuniga-Sanchez, ... Neuron 108 (1), 111-127. e6, 2020 | 45 | 2020 |
DNA methylation study of Huntington’s disease and motor progression in patients and in animal models AT Lu, P Narayan, MJ Grant, P Langfelder, N Wang, S Kwak, H Wilkinson, ... Nature communications 11 (1), 4529, 2020 | 57 | 2020 |
Package ‘PropClust’ JMO Ranola, K Lange, S Horvath, P Langfelder, MP Langfelder | | 2018 |
anRichment tutorial P Langfelder | | 2018 |
No reliable gene expression biomarkers of current or impending neurocognitive impairment in peripheral blood monocytes of persons living with HIV A Quach, S Horvath, N Nemanim, D Vatakis, MD Witt, EN Miller, R Detels, ... Journal of neurovirology, 1-12, 2018 | 6 | 2018 |
Elevated TREM2 gene dosage reprograms microglia responsivity and ameliorates pathological phenotypes in Alzheimer’s disease models CYD Lee, A Daggett, X Gu, LL Jiang, P Langfelder, X Li, N Wang, Y Zhao, ... Neuron 97 (5), 1032-1048. e5, 2018 | 319 | 2018 |
Package ‘WGCNA’ P Langfelder, MP Langfelder, LT Rcpp | 4 | 2018 |
MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice P Langfelder, F Gao, N Wang, D Howland, S Kwak, TF Vogt, JS Aaronson, ... PloS one 13 (1), e0190550, 2018 | 49 | 2018 |