| Obesity-induced inflammation exacerbates clonal hematopoiesis SK Pasupuleti, B Ramdas, SS Burns, LR Palam, R Kanumuri, R Kumar, ... The Journal of Clinical Investigation 133 (11), 2023 | 33 | 2023 |
| Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway LR Palam, B Ramdas, K Pickerell, SK Pasupuleti, R Kanumuri, ... JCI insight 8 (9), 2023 | 3 | 2023 |
| Potential clinical use of azacitidine and MEK inhibitor combination therapy in PTPN11-mutated juvenile myelomonocytic leukemia SK Pasupuleti, K Chao, B Ramdas, R Kanumuri, LR Palam, S Liu, J Wan, ... Molecular Therapy 31 (4), 986-1001, 2023 | 5 | 2023 |
| 3149–OBESITY INDUCED INFLAMMATION EXACERBATES CLONAL HEMATOPOIESIS SK Pasupuleti, B Ramdas, SS Burns, LR Palam, R Kanumuri, R Kumar, ... Experimental Hematology 124, S124, 2023 | 1 | 2023 |
| PI3K Signaling Is Essential for Leukemic Transformation of Tet2 Mutated Pre-Leukemic Hematopoietic Stem Cells LR Palam, B Ramdas, K Pickerell, ML Capitano, R Kapur Blood 140 (Supplement 1), 5736-5736, 2022 | | 2022 |
| Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal A Aljoufi, C Zhang, J Ropa, W Chang, LR Palam, S Cooper, B Ramdas, ... Blood, The Journal of the American Society of Hematology 140 (11), 1263-1277, 2022 | 9 | 2022 |
| Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells B Ramdas, LD Yuen, LR Palam, R Patel, SK Pasupuleti, V Jideonwo, ... Molecular Therapy 30 (7), 2505-2521, 2022 | 4 | 2022 |
| RESISTANCE OF TET2 MUTANT PRELEUKEMIC STEM CELLS TO EXTRAPHYSIOLOGIC OXYGEN SHOCK PROVIDES POTENTIAL INSIGHT INTO THEIR GROWTH ADVANTAGE A Aljoufi, J Ropa, S Cooper, B Ramdas, LR Palam, R Kapur, H Broxmeyer EXPERIMENTAL HEMATOLOGY 100, S33-S33, 2021 | | 2021 |
| 2011–RESISTANCE OF TET2 MUTANT PRELEUKEMIC STEM CELLS TO EXTRAPHYSIOLOGIC OXYGEN SHOCK PROVIDES POTENTIAL INSIGHT INTO THEIR GROWTH ADVANTAGE A Aljoufi, J Ropa, S Cooper, B Ramdas, LR Palam, R Kapur, H Broxmeyer Experimental Hematology 100, S32-S33, 2021 | | 2021 |
| Exploiting the proteasome to overcome RAS and WT1 mutation mediated resistance to FLT-3 inhibition in acute myeloid leukemia S Rangaraju, SK Pasupuleti, S Marino, DN Petrusca, LD Cripe, B Ramdas, ... Cancer Research 80 (16_Supplement), 800-800, 2020 | | 2020 |
| Driver mutations in leukemia promote disease pathogenesis through a combination of cell-autonomous and niche modulation B Ramdas, RS Mali, LR Palam, R Pandey, Z Cai, SK Pasupuleti, ... Stem cell reports 15 (1), 95-109, 2020 | 14 | 2020 |
| Combined Heterozygous Loss of Tet2 and Dnmt3a Along with Expression of Flt3ITD/WT results in Acute Myeloid Leukemia Which Responds to a Combination of FLT3 Inhibitor, APE1 … B Ramdas, LR Palam, RS Mali, Z Cai, R Pandey, R Kapur Blood 134, 3754, 2019 | | 2019 |
| Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid … LR Palam, B Ramdas, K Pickerell, R Kapur Blood 134, 723, 2019 | | 2019 |
| Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits … S Rangaraju, S Marino, GD Roodman, LD Cripe, B Ramdas, LR Palam, ... Blood 134, 5051, 2019 | | 2019 |
| Blimp1 prevents methylation of Foxp3 and loss of regulatory T cell identity at sites of inflammation G Garg, A Muschaweckh, H Moreno, A Vasanthakumar, S Floess, ... Cell reports 26 (7), 1854-1868. e5, 2019 | 114 | 2019 |
| Inhibition of inflammatory signaling in Tet2 mutant preleukemic cells mitigates stress-induced abnormalities and clonal hematopoiesis Z Cai, JJ Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ... Cell stem cell 23 (6), 833-849. e5, 2018 | 308 | 2018 |
| Temporal and Spatially Regulated Oncogenic KIT Expression and Loss of Dnmt3a Cooperate to Drive MPN Development: Role of PI3Kinase in Dnmt3a Loss Induced Hyperproliferation in … LR Palam, B Ramdas, S reddy Srivatsan, SC Janga, A Roers, A Gerbaulet, ... Blood 132, 3055, 2018 | | 2018 |
| Identification of Beta-Catenin As a Novel Ubiquitin-Regulated Target of Combined Flβ3/Syk-and Proteasome Inhibitors for Interruption of LSC Signaling in Poor-Risk AML S Rangaraju, S Marino, DN Petrusca, LD Cripe, KJ Sargent, ... Blood 132, 3949, 2018 | | 2018 |
| Downregulation of Morrbid in Tet2-Deficient Preleukemic Cells Overcomes Resistance to Inflammatory Stress and Mitigates Clonal Hematopoiesis Z Cai, J Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ... Blood 132, 1288, 2018 | 1 | 2018 |
| Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway LR Palam, RS Mali, B Ramdas, SN Srivatsan, V Visconte, RV Tiu, ... JCI insight 3 (4), 2018 | 23 | 2018 |
