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Gottfried Otting
Gottfried Otting
Professor of Structural Biology, The Australian National University
在 anu.edu.au 的电子邮件经过验证 - 首页
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(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5′-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing …
YJ Tan, EH Abdelkader, E Tarcoveanu, A Maleckis, C Nitsche, G Otting
Biochemistry, 2024
2024
Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5′-Difluoroleucine in a Protein
RL Frkic, YJ Tan, EH Abdelkader, A Maleckis, E Tarcoveanu, C Nitsche, ...
Biochemistry, 2024
12024
Genetic Encoding of Fluoro-l-tryptophans for Site-Specific Detection of Conformational Heterogeneity in Proteins by NMR Spectroscopy
H Qianzhu, EH Abdelkader, G Otting, T Huber
Journal of the American Chemical Society 146 (19), 13641-13650, 2024
12024
Correction to “Electrostatic Contribution to 19F Chemical Shifts in Fluorotryptophans in Proteins”
M Maxwell, YJ Tan, R Lee, T Huber, G Otting
Biochemistry 63 (3), 367-367, 2024
2024
A lanthanide tag for a complementary set of pseudocontact shifts
L Topping, AP Welegedara, M Judd, EH Abdelkader, N Cox, G Otting, ...
Chemical Communications, 2024
2024
Electrostatic Contribution to 19F Chemical Shifts in Fluorotryptophans in Proteins
M Maxwell, YJ Tan, R Lee, T Huber, G Otting
Biochemistry 62 (22), 3255-3264, 2023
32023
Genetic Encoding of 7-Aza-l-tryptophan: Isoelectronic Substitution of a Single CH-Group in a Protein for a Nitrogen Atom for Site-Selective Isotope Labeling
EH Abdelkader, H Qianzhu, T Huber, G Otting
ACS sensors 8 (11), 4402-4406, 2023
12023
3D structure of the transient intermediate of the enzyme–substrate complex of sortase A reveals how calcium binding and substrate recognition cooperate in substrate activation
JL Chen, X Wang, F Yang, B Li, G Otting, XC Su
ACS Catalysis 13 (17), 11610-11624, 2023
52023
Improved spectral resolution of [13C,1H]-HSQC spectra of aromatic amino acid residues in proteins produced by cell-free synthesis from inexpensive 13C …
D Van Raad, T Huber, G Otting
Journal of Biomolecular NMR 77 (4), 183-190, 2023
12023
Cell-free synthesis of proteins with selectively C-labelled methyl groups from inexpensive precursors
D Van Raad, G Otting, T Huber
Magnetic Resonance 4 (2), 187-197, 2023
12023
Probing Ligand Binding Sites on Large Proteins by NMR Spectroscopy of Genetically Encoded Non-Canonical Amino Acids
K Ekanayake, M Mahawaththa, H Qianzhu, E Abdelkader, J George, ...
The Australian National University, 2023
2023
Probing ligand binding sites on large proteins by nuclear magnetic resonance spectroscopy of genetically encoded non-canonical amino acids
KB Ekanayake, MC Mahawaththa, H Qianzhu, EH Abdelkader, J George, ...
Journal of Medicinal Chemistry 66 (7), 5289-5304, 2023
62023
Site-selective generation of lanthanoid binding sites on proteins using 4-fluoro-2, 6-dicyanopyridine
S Mekkattu Tharayil, MC Mahawaththa, A Feintuch, A Maleckis, S Ullrich, ...
Magnetic Resonance 3 (2), 169-182, 2022
12022
InOOH-mediated intergrown heterojunctions for enhanced photocatalytic Performance: Assembly and interfacial charge carrier transferring
F Nekouei, X Wen, Z Zheng, Q Sun, T Lu, H Orton, F Kremer, S Nekouei, ...
Chemical Engineering Journal 442, 136355, 2022
82022
DEER experiments reveal fundamental differences between calmodulin complexes with IQ and MARCKS peptides in solution
C Jash, A Feintuch, S Nudelman, N Manukovsky, EH Abdelkader, ...
Structure 30 (6), 813-827. e5, 2022
42022
Localising nuclear spins by pseudocontact shifts from a single tagging site
HW Orton, EH Abdelkader, L Topping, SJ Butler, G Otting
Magnetic Resonance 3 (1), 65-76, 2022
62022
Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir
S Ullrich, KB Ekanayake, G Otting, C Nitsche
Bioorganic & Medicinal Chemistry Letters 62, 128629, 2022
1762022
Genetic Encoding of Cyanopyridylalanine for In‐Cell Protein Macrocyclization by the Nitrile–Aminothiol Click Reaction
EH Abdelkader, H Qianzhu, J George, RL Frkic, CJ Jackson, C Nitsche, ...
Angewandte Chemie 134 (13), e202114154, 2022
262022
Paramagnetic chemical probes for studying biological macromolecules
Q Miao, C Nitsche, H Orton, M Overhand, G Otting, M Ubbink
Chemical Reviews 122 (10), 9571-9642, 2022
642022
Site-Specific Incorporation of 7-Fluoro-L-tryptophan into Proteins by Genetic Encoding to Monitor Ligand Binding by 19F NMR Spectroscopy
H Qianzhu, EH Abdelkader, ID Herath, G Otting, T Huber
ACS sensors 7 (1), 44-49, 2022
122022
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