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Deli Huang
Deli Huang
Life Sciences Institute, ZheJiang University
在 zju.edu.cn 的电子邮件经过验证
标题
引用次数
年份
Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4
M Yuan, L Peng, D Huang, A Gavin, F Luan, J Tran, Z Feng, X Zhu, ...
Structure, 2024
12024
Covid-19 antibodies and uses thereof
D Sok, J Jardine, E Landais, D Burton, T Rogers, F Zhao, D Huang
US Patent App. 17/923,313, 2023
2023
Broadening a SARS-CoV-1–neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution
F Zhao, M Yuan, C Keating, N Shaabani, O Limbo, C Joyce, J Woehl, ...
Science Signaling 16 (798), eabk3516, 2023
132023
Disease in the Pld4thss/thss model of murine lupus requires TLR9
AL Gavin, TR Blane, TC Thinnes, E Gerlt, A Marshak-Rothstein, D Huang, ...
Immunohorizons 7 (8), 577-586, 2023
22023
B cell receptor modification in b cells
JE Voss, R Andrabi, DR Burton, D Huang, A Gonzalez-Martin
US Patent App. 16/642,810, 2023
2023
Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
F Zhao, C Keating, G Ozorowski, N Shaabani, IM Francino-Urdaniz, ...
Iscience 25 (9), 2022
72022
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
W He, M Yuan, S Callaghan, R Musharrafieh, G Song, M Silva, N Beutler, ...
Science translational medicine 14 (657), eabl9605, 2022
242022
In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice
AD Nahmad, CR Lazzarotto, N Zelikson, T Kustin, M Tenuta, D Huang, ...
Nature biotechnology 40 (8), 1241-1249, 2022
392022
Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors, including endolysosomal TLRs and a STING dependent sensing pathway.
D Nemazee, L Peng, T Blane, D Huang, A Gavin
The Journal of Immunology 208 (1_Supplement), 158.05-158.05, 2022
2022
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection
P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ...
Science translational medicine 14 (637), eabi9215, 2022
1362022
A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies
F Ferrara, MF Erasmus, S D’Angelo, C Leal-Lopes, AA Teixeira, ...
Nature communications 13 (1), 462, 2022
282022
Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors
AL Gavin, D Huang, TR Blane, TC Thinnes, Y Murakami, R Fukui, ...
Nature Communications 12 (1), 5874, 2021
302021
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern
H Cho, KK Gonzales-Wartz, D Huang, M Yuan, M Peterson, J Liang, ...
Science translational medicine 13 (616), eabj5413, 2021
872021
SARS-CoV-2 serology status detected by commercialized platforms distinguishes previous infection and vaccination adaptive immune responses
RT Suhandynata, NJ Bevins, JT Tran, D Huang, MA Hoffman, K Lund, ...
The journal of applied laboratory medicine 6 (5), 1109-1122, 2021
332021
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
M Yuan, D Huang, CCD Lee, NC Wu, AM Jackson, X Zhu, H Liu, L Peng, ...
Science 373 (6556), 818-823, 2021
3582021
A rapid assay for SARS-CoV-2 neutralizing antibodies that is insensitive to antiretroviral drugs
D Huang, JT Tran, L Peng, L Yang, RT Suhandynata, MA Hoffman, ...
The Journal of Immunology 207 (1), 344-351, 2021
52021
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
G Song, W He, S Callaghan, F Anzanello, D Huang, J Ricketts, JL Torres, ...
Nature communications 12 (1), 2938, 2021
2842021
A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection
H Liu, M Yuan, D Huang, S Bangaru, F Zhao, CCD Lee, L Peng, ...
Cell host & microbe 29 (5), 806-818. e6, 2021
562021
Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2
X Zhou, F Ma, J Xie, M Yuan, Y Li, N Shaabani, F Zhao, D Huang, NC Wu, ...
Cell reports 35 (6), 2021
272021
In-vivo engineering of B cells elicits memory retention and allows for secretion of broadly neutralizing antibodies in mice
AD Nahmad, C Lazzarotto, N Zelikson, T Kustin, M Tenuta, D Huang, ...
The Journal of Immunology 206 (1_Supplement), 59.14-59.14, 2021
2021
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