Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits CY Chen, TT Chen, YCA Feng, M Yu, SC Lin, RJ Longchamps, SH Wang, ... Cell genomics 3 (12), 2023 | 6 | 2023 |
Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis LK Guo, Y Su, YYN Zhang, H Yu, Z Lu, WQ Li, YF Yang, X Xiao, H Yan, ... Military Medical Research 10 (1), 1-15, 2023 | 9 | 2023 |
Profiling the inflammatory bowel diseases using genetics, serum biomarkers, and smoking information R Liu, D Li, T Haritunians, Y Ruan, MJ Daly, H Huang, DPB McGovern Iscience 26 (10), 2023 | | 2023 |
Methods and systems for stratifying inflammatory bowel disease patients DP McGovern, D Li, R Yunfeng, R Liu, M Daly, H Huang US Patent App. 18/190,731, 2023 | | 2023 |
The impact of rare protein coding genetic variation on adult cognitive function CY Chen, R Tian, T Ge, M Lam, G Sanchez-Andrade, T Singh, L Urpa, ... Nature Genetics, 1-12, 2023 | 18 | 2023 |
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia YHH Hsu, G Pintacuda, R Liu, E Nacu, A Kim, K Tsafou, N Petrossian, ... Iscience 26 (5), 2023 | 2 | 2023 |
Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries Z Liu, R Liu, H Gao, S Jung, X Gao, R Sun, X Liu, Y Kim, HS Lee, Y Kawai, ... Nature Genetics, 1-11, 2023 | 37 | 2023 |
A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis H Ma, T Hu, W Tao, J Tong, Z Han, D Herndler-Brandstetter, Z Wei, R Liu, ... Cell Research, 1-17, 2023 | 10 | 2023 |
Haplotype-specific MAPK3 expression in 16p11.2 deletion contributes to variable neurodevelopment F Liu, C Liang, Z Li, S Zhao, H Yuan, R Yao, Z Qin, S Shangguan, ... Brain, awad071, 2023 | 2 | 2023 |
GWAS Quality Score for Evaluating Associated Regions in GWAS Analyses S Awasthi, CY Chen, M Lam, H Huang, S Ripke, CA Altar Bioinformatics, 2023 | | 2023 |
MCPIP-1-Mediated Immunosuppression of Neutrophils Exacerbates Acute Bacterial Peritonitis and Liver Injury J Lin, Z Lu, G Li, C Zhang, H Lu, S Gao, R Zhu, H Huang, K Aden, J Wang, ... Journal of Innate Immunity 15 (1), 262-282, 2023 | 2 | 2023 |
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts Y Wang, S Namba, E Lopera, S Kerminen, K Tsuo, K Läll, M Kanai, ... Cell Genomics, 100241, 2023 | 51 | 2023 |
Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases K Yuan, RJ Longchamps, AF Pardinas, M Yu, TT Chen, SC Lin, Y Chen, ... medRxiv, 2023.01. 07.23284293, 2023 | 18 | 2023 |
Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology M Lam, CY Chen, WD Hill, C Xia, R Tian, DF Levey, J Gelernter, MB Stein, ... Nature Communications 13 (1), 6868, 2022 | 6 | 2022 |
Taiwan Biobank: A rich biomedical research database of the Taiwanese population YCA Feng, CY Chen, TT Chen, PH Kuo, YH Hsu, HI Yang, WJ Chen, ... Cell Genomics 2 (11), 2022 | 40 | 2022 |
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease W Zhou, M Kanai, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, Y Wang, ... Cell Genomics 2 (10), 100192, 2022 | 193 | 2022 |
Multi-omics analysis identifies rare variation in leptin/PPAR gene sets and hypermethylation of ABCG1 contribute to antipsychotics-induced metabolic syndromes W Zhou, J Sun, C Huai, Y Liu, L Chen, Z Yi, Q Lv, C Song, W Zhu, C Liu, ... Molecular Psychiatry, 1-11, 2022 | | 2022 |
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility A Sazonovs, CR Stevens, GR Venkataraman, K Yuan, B Avila, MT Abreu, ... Nature genetics 54 (9), 1275-1283, 2022 | 91* | 2022 |
Human iPSC-derived neuron of 16p11.2 deletion reveals haplotype-specific expression of MAPK3 and its contribution to variable NDD phenotypes F Liu, C Liang, Z Li, S Zhao, S Shangguan, H Yuan, R Yao, Z Qin, ... bioRxiv, 2022.07. 10.498576, 2022 | | 2022 |
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations T Ge, MR Irvin, A Patki, V Srinivasasainagendra, YF Lin, HK Tiwari, ... Genome medicine 14 (1), 70, 2022 | 57 | 2022 |