Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages H Marcotte, Y Cao, F Zuo, L Simonelli, JC Sammartino, M Pedotti, R Sun, ... Proceedings of the National Academy of Sciences 121 (3), e2315354120, 2024 | 8 | 2024 |
Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer G Guerrini, D Mehn, F Fumagalli, S Gioria, M Pedotti, L Simonelli, ... International Journal of Molecular Sciences 24 (19), 14875, 2023 | | 2023 |
Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology F Peissert, M Pedotti, R Corbellari, L Simonelli, R De Gasparo, ... Global Challenges 7 (10), 2300088, 2023 | 1 | 2023 |
19n01, a broadly neutralizing antibody against omicron BA. 1, BA. 2, BA. 4/5, and other SARS-CoV-2 variants of concern M García-Vega, EA Melgoza-González, S Hernández-Valenzuela, ... Iscience 26 (4), 2023 | 3 | 2023 |
Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course J Muri, V Cecchinato, A Cavalli, AA Shanbhag, M Matkovic, M Biggiogero, ... Nature immunology 24 (4), 604-611, 2023 | 49 | 2023 |
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer N Bancaro, B Calì, M Troiani, AR Elia, RA Arzola, G Attanasio, P Lai, ... Cancer Cell 41 (3), 602-619. e11, 2023 | 42 | 2023 |
Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein F Bianchini, V Crivelli, ME Abernathy, C Guerra, M Palus, J Muri, ... Science Immunology 8 (81), eade0958, 2023 | 47 | 2023 |
A conformational switch controlling the toxicity of the prion protein K Frontzek, M Bardelli, A Senatore, A Henzi, RR Reimann, S Bedir, ... Nature structural & molecular biology 29 (8), 831-840, 2022 | 21 | 2022 |
Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules M Stravalaci, I Pagani, EM Paraboschi, M Pedotti, A Doni, F Scavello, ... Nature Immunology 23 (2), 275-286, 2022 | 114 | 2022 |
19n01, a Broadly Neutralizing Antibody Against Omicron BA. 1, BA. 2, BA. 4/5, and Other SARS-CoV-2 Variants of Concern D Hinojosa-Trujillo, MA Llamas-Covarrubias, M Loza-Lopez, ... NATURE COMMUNICATIONS, 2022 | | 2022 |
Human monoclonal antibodies to the spike subdomain 1 neutralize SARS-CoV-2 and its variants of concern F Bianchini, V Crivelli, ME Abernathy, C Guerra, M Palus, H Marcotte, ... Swiss Medical Weekly, 10S-10S, 2022 | | 2022 |
Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2 (preprint) F Bianchini, V Crivelli, ME Abernathy, C Guerra, M Palus, J Muri, ... | | 2022 |
Systematic development of peptide inhibitors targeting the CXCL12/HMGB1 interaction J Sgrignani, V Cecchinato, EMA Fassi, G D’Agostino, M Garofalo, ... Journal of Medicinal Chemistry 64 (18), 13439-13450, 2021 | 14 | 2021 |
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice R De Gasparo, M Pedotti, L Simonelli, P Nickl, F Muecksch, I Cassaniti, ... Nature 593 (7859), 424-428, 2021 | 121 | 2021 |
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface F Bertoglio, D Meier, N Langreder, S Steinke, U Rand, L Simonelli, ... Nature communications 12 (1), 1-15, 2021 | 84 | 2021 |
Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease R De Gasparo, M Pedotti, L Simonelli, P Nickl, F Muecksch, I Cassaniti, ... bioRxiv, 2021.01. 22.427567, 2021 | 1 | 2021 |
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity M Bardelli, K Frontzek, L Simonelli, S Hornemann, M Pedotti, F Mazzola, ... PLoS pathogens 14 (10), e1007335, 2018 | 22 | 2018 |
Mapping Antibody Epitopes by Solution NMR Spectroscopy: Practical Considerations L Simonelli, M Pedotti, M Bardelli, S Jurt, O Zerbe, L Varani Epitope Mapping Protocols, 29-51, 2018 | 14 | 2018 |
Label-free biosensor detection of endocrine disrupting compounds using engineered estrogen receptors R La Spina, VEV Ferrero, V Aiello, M Pedotti, L Varani, T Lettieri, ... Biosensors 8 (1), 1, 2017 | 25 | 2017 |
A human bi-specific antibody against Zika virus with high therapeutic potential J Wang, M Bardelli, DA Espinosa, M Pedotti, TS Ng, S Bianchi, ... Cell 171 (1), 229-241. e15, 2017 | 142 | 2017 |