| PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration SL Peterson, A Krishnan, D Patel, A Khanehzar, A Lad, J Shaughnessy, ... Pharmaceuticals 17 (4), 517, 2024 | | 2024 |
| Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human … A Krishnan, DG Callanan, VG Sendra, A Lad, S Christian, R Earla, ... Pharmaceuticals 17 (4), 481, 2024 | | 2024 |
| Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function in Age-Related … MJ Tolentino, AJ Tolentino, EM Tolentino, A Krishnan, MA Genead Pharmaceuticals 16 (12), 1735, 2023 | 2 | 2023 |
| Sustained vision recovery by OSK gene therapy in a mouse model of glaucoma MM Karg, YR Lu, N Refaian, J Cameron, E Hoffmann, C Hoppe, ... Cellular Reprogramming 25 (6), 288-299, 2023 | 5 | 2023 |
| PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: A potential treatment for age related macular degeneration A Krishnan, VG Sendra, D Patel, A Lad, MK Greene, P Smyth, ... Frontiers in Immunology 14, 1237016, 2023 | 5 | 2023 |
| Sialic Acid Mimetic Microglial SIGLEC Agonistic Nanoparticle: Potential to Restore Retinal Homeostasis and Regain Visual Function in AMD MJ Tolentino, AJ Tolentino, A Krishnan, MA Genead Preprints, 2023 | | 2023 |
| Post injury treatment with intravitreal AAV2-soluble Fas ligand restores retinal microglia homeostasis and rescues retinal ganglion cell function in a mouse model of glaucoma MS Gregory-Ksander, A Krishnan, M Shrestha, K Nguyen, ... Investigative Ophthalmology & Visual Science 64 (8), 2583-2583, 2023 | | 2023 |
| Modulation of macrophages and complement dysfunction in nonexudative age-related macular degeneration utilizing a sialic-acid coated nanoparticle BD Kuppermann, D Callanan, T Hassan, M Tolentino, C Scott, M Genead, ... Investigative Ophthalmology & Visual Science 64 (8), 3239-3239, 2023 | 2 | 2023 |
| Modulation of retinal inflammatory macrophages by sialic-acid coated nanoparticles as novel mechanism for nonexudative AMD treatment A Krishnan, D Patel, VG Sendra, A Lad, D Callanan, T Hassan, ... Investigative Ophthalmology & Visual Science 64 (8), 2730-2730, 2023 | 2 | 2023 |
| Targeting self-recognition pattern receptors on retina immune cells with an engineered glycan-coated nanoparticle as a novel therapy for nonexudative AMD D Patel, A Lad, D Callanan, T Hassan, M Tolentino, C Scott, M Genead, ... Investigative Ophthalmology & Visual Science 64 (8), 2959-2959, 2023 | 2 | 2023 |
| Anti-inflammatory role of a glycan-coated nanoparticle in modulating macrophages and complement in non-exudative AMD A Krishnan, R Shinde, M Tolentino, D Callanan, D Kunimoto, M Genead Investigative Ophthalmology & Visual Science 63 (7), 3163–F0437-3163–F0437, 2022 | | 2022 |
| Compositions and methods of fas inhibition D Zacks, A Kocab, J Freshley, M Gregory-Ksander, A Krishnan, ... US Patent App. 17/026,005, 2021 | 1 | 2021 |
| Reprogramming to recover youthful epigenetic information and restore vision Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang, DL Vera, Q Zeng, ... Nature 588 (7836), 124-129, 2020 | 551 | 2020 |
| Intravitreal administration of AAV2. soluble Fas ligand gene therapy following glaucoma injury restores retinal ganglion cell function and stops disease progression MS Gregory-Ksander, M Shrestha, K Nguyen, A Marshak-Rothstein, ... Investigative Ophthalmology & Visual Science 61 (7), 2366-2366, 2020 | | 2020 |
| InflaMab: A novel NLRP3 Inflammasome inhibitor provides neuroprotection in a mouse model of glaucoma M Chemaly, A Krishnan, AJ Bjourson, A Peace, MS Gregory-Ksander, ... Investigative Ophthalmology & Visual Science 61 (7), 2365-2365, 2020 | | 2020 |
| Reversal of aging-induced and glaucoma-induced vision loss by in vivo epigenetic reprogramming B Ksander, Y Lu, A Krishnan, B Brommer, X Tian, M Meer, D Vera, ... Investigative Ophthalmology & Visual Science 61 (7), 2364-2364, 2020 | 2 | 2020 |
| InflaMab: A novel NLRP3 Inflammasome inhibitor provides neuroprotection in a mouse model of glaucoma VE McGilligan, M El Chemaly, A Krishnan, AJ Bjourson, A Peace ARVO, 2365, 2020 | | 2020 |
| A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma A Krishnan, AJ Kocab, DN Zacks, A Marshak-Rothstein, ... Journal of neuroinflammation 16, 1-15, 2019 | 102 | 2019 |
| Reversal of ageing-and injury-induced vision loss by Tet-dependent epigenetic reprogramming Y Lu, A Krishnan, B Brommer, X Tian, M Meer, DL Vera, C Wang, Q Zeng, ... BioRxiv, 710210, 2019 | 26 | 2019 |
| Pharmacologic inhibition of the NLRP3 inflammasome-a novel neuroprotective therapy for glaucoma A Krishnan, M Dua, CH Mitchell, W Lu, MS Gregory-Ksander Investigative Ophthalmology & Visual Science 60 (9), 2256-2256, 2019 | 3 | 2019 |
