关注
David Joy
David Joy
未知所在单位机构
在 dnli.com 的电子邮件经过验证
标题
引用次数
年份
Language Models are Alignable Decision-Makers: Dataset and Application to the Medical Triage Domain
B Hu, B Ray, A Leung, A Summerville, D Joy, C Funk, A Basharat
arXiv preprint arXiv:2406.06435, 2024
2024
ETV: SGSH, a brain-penetrant enzyme transport vehicle for SGSH, improves lysosomal and microglial morphology, degeneration and cognitive behavior in MPS IIIA mice
ST Masoud, H Nguyen, C Discenza, D Joy, J Simms, I Lo, YY Chun, ...
Molecular Genetics and Metabolism 141 (2), 107954, 2024
2024
Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes
X Wang, VV Bondar, OB Davis, MT Maloney, M Agam, MY Chin, ACN Ho, ...
Elife 12, e87255, 2023
62023
CD98hc is a target for brain delivery of biotherapeutics
KS Chew, RC Wells, A Moshkforoush, D Chan, KJ Lechtenberg, HL Tran, ...
nature communications 14 (1), 5053, 2023
122023
Optogenetic control of Wnt signaling models cell-intrinsic embryogenic patterning using 2D human pluripotent stem cell culture
NA Repina, HJ Johnson, X Bao, JA Zimmermann, DA Joy, SZ Bi, RS Kane, ...
Development 150 (14), 2023
102023
A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models
B van Lengerich, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, ...
Nature neuroscience 26 (3), 416-429, 2023
842023
Rab12 regulates LRRK2 activity by promoting its localization to lysosomes
VV Bondar, X Wang, OB Davis, MT Maloney, M Agam, MY Chin, ACN Ho, ...
bioRxiv, 2023.02. 21.529466, 2023
42023
Quantitative Bioimaging of Microglial Response to Brain-Targeted Treatment Using Deep Learning Based Morphometry
D Joy, D Xia, K Monroe, P Sanchez, M Calvert
Microscopy and Microanalysis 28 (S1), 1422-1423, 2022
2022
Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids
AC Silva, OB Matthys, DA Joy, MA Kauss, V Natarajan, MH Lai, D Turaga, ...
Cell stem cell 28 (12), 2137-2152. e6, 2021
812021
Axial elongation of caudalized human organoids mimics aspects of neural tube development
ARG Libby, DA Joy, NH Elder, EA Bulger, MZ Krakora, EA Gaylord, ...
Development 148 (12), dev198275, 2021
582021
Deep neural net tracking of human pluripotent stem cells reveals intrinsic behaviors directing morphogenesis
DA Joy, ARG Libby, TC McDevitt
Stem cell reports 16 (5), 1317-1330, 2021
172021
SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19
JA Perez-Bermejo, S Kang, SJ Rockwood, CR Simoneau, DA Joy, ...
Science translational medicine 13 (590), eabf7872, 2021
1422021
Engineering the spatiotemporal mosaic self-patterning of pluripotent stem cells
ARG Libby, DA Joy, TC McDevitt
Programmed Morphogenesis: Methods and Protocols, 105-116, 2021
32021
Silencing of E-cadherin in induced human pluripotent stem cells promotes extraembryonic fates accompanying multilineage differentiation
ARG Libby, I Vasic, DA Joy, MZ Krakora, FN Mendoza-Camacho, ...
bioRxiv, 2020.11. 01.363713, 2020
2020
SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients
JA Pérez-Bermejo, S Kang, SJ Rockwood, CR Simoneau, DA Joy, ...
BioRxiv, 2020
872020
Cardiac Cell-Derived Matrices Impart Age-Specific Functional Properties to Human Cardiomyocytes
MA Kauss, SJ Rockwood, AC Silva, DA Joy, N Mendoza-Camacho, ...
bioRxiv, 2020.07. 31.231480, 2020
22020
Bi-directional Impacts of Heterotypic Interactions in Engineered 3D Human Cardiac Microtissues Revealed by Single-Cell RNA-Sequencing and Functional Analysis
TA Hookway, OB Matthys, DA Joy, JE Sepulveda, R Thomas, TC McDevitt
bioRxiv, 2020.07. 06.190504, 2020
82020
Developmental co-emergence of cardiac and gut tissues modeled by human iPSC-derived organoids
AC Silva, OB Matthys, DA Joy, MA Kauss, V Natarajan, MH Lai, D Turaga, ...
BioRxiv, 2020.04. 30.071472, 2020
242020
Single-cell determination of cardiac microtissue structure and function using light sheet microscopy
D Turaga, OB Matthys, TA Hookway, DA Joy, M Calvert, TC McDevitt
Tissue Engineering Part C: Methods 26 (4), 207-215, 2020
132020
Axial elongation of caudalized human organoids mimics neural tube development
ARG Libby, DA Joy, NH Elder, EA Bulger, MZ Krakora, EA Gaylord, ...
BioRxiv, 2020.03. 05.979732, 2020
132020
系统目前无法执行此操作,请稍后再试。
文章 1–20