Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice AL Pan, M Audrain, E Sakakibara, R Joshi, X Zhu, Q Wang, M Wang, ... Frontiers in Aging Neuroscience 16, 1400447, 2024 | | 2024 |
Divergent landscapes of A-to-I editing in postmortem and living human brain M Rodriguez de los Santos, BH Kopell, A Buxbaum Grice, G Ganesh, ... Nature Communications 15 (1), 5366, 2024 | | 2024 |
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Divergent landscapes of A-to-I editing in postmortem and living human brain MR de Los Santos, BH Kopell, AB Grice, G Ganesh, A Yang, P Amini, ... medRxiv, 2024 | | 2024 |
An algorithm to identify patients aged 0–3 with rare genetic disorders BD Webb, LY Lau, D Tsevdos, RA Shewcraft, D Corrigan, L Shi, S Lee, ... Orphanet Journal of Rare Diseases 19 (1), 183, 2024 | | 2024 |
Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop S Bunyavanich, PM Becker, MC Altman, J Lasky-Su, C Ober, K Zengler, ... Journal of Allergy and Clinical Immunology 153 (4), 954-968, 2024 | 3 | 2024 |
Targeting resistance mechanisms to AR-targeted therapy in prostate cancer through inhibition of CREBBP/EP300 BV Dougherty, BC Thomas, AM Walsh, V Calvo, KE Ware, AJ Armstrong, ... Cancer Research 84 (6_Supplement), 6544-6544, 2024 | | 2024 |
Abstract P33: Leveraging probabilistic causal disease models to understand molecular pathways and target resistance mechanisms in Multiple Myeloma with the CREBBP and EP300 … AE Roder, AM Walsh, TK Krebs, V Calvo, BV Dougherty, P Smith, ... Blood Cancer Discovery 5 (2_Supplement), P33-P33, 2024 | | 2024 |
Establishing the Automatic Identification of Clinical Trial Cohorts from Electronic Health Records by Matching Normalized Eligibility Criteria and Patient Clinical Characteristics K Lee, Y Mai, Z Liu, K Raja, MK Higashi, T Jun, M Ma, T Wang, L Ai, ... medRxiv, 2024.02. 28.24303396, 2024 | | 2024 |
Pan-cancer proteogenomics characterization of tumor immunity F Petralia, W Ma, TM Yaron, FP Caruso, N Tignor, JM Wang, ... Cell 187 (5), 1255-1277. e27, 2024 | 5 | 2024 |
Transcriptomic landscape of human induced pluripotent stem cell-derived osteogenic differentiation identifies a regulatory role of KLF16 Y Ru, M Ma, X Zhou, D Kriti, N Cohen, S D’Souza, C Schaniel, ... bioRxiv, 2024 | | 2024 |
BIOACTIVE INTERLEUKIN-1 DETECTED IN IBD PATIENT INTESTINAL BIOPSIES IS A HALLMARK OF ULCERS AND CORRELATES WITH TRANSCRIPTOMIC ASSESSMENTS, INCLUDING AN ULCER-ASSOCIATED GENE … M Losa, M Field, L Collen, J Barends, A Ringel, M Bresnahan, J Yang, ... Gastroenterology 166 (3), S77-S78, 2024 | | 2024 |
Anti-correlated feature selection prevents false discovery of subpopulations in scRNAseq SR Tyler, D Lozano-Ojalvo, E Guccione, EE Schadt Nature Communications 15 (1), 699, 2024 | 2 | 2024 |
Multiomic foundations of human prefrontal cortex tissue function BH Kopell, DA Kaji, LE Liharska, E Vornholt, A Valentine, A Lund, ... medRxiv, 2024.05. 17.24307537, 2024 | | 2024 |
Characterizing cell type specific transcriptional differences between the living and postmortem human brain. E Vornholt, LE Liharska, E Cheng, A Hashemi, YJ Park, K Ziafat, L Wilkins, ... medRxiv, 2024.05. 01.24306590, 2024 | 1 | 2024 |
OP17 IBD ulcers are characterized by bioactive interleukin-1 and transcriptomic hallmarks of stromal cell state reprogramming V Mitsialis, M Losa, M Field, L Collen, J Barends, A Ringel, M Bresnahan, ... Journal of Crohn's and Colitis 18 (Supplement_1), i32-i33, 2024 | | 2024 |
OP28 Defective STAT3 signaling in refractory Very Early Onset Inflammatory Bowel Disease is associated with a transcriptional signature which predicts response to anti-IL23 … L Collen, N Beckmann, V Mitsialis, A Eran, M Field, D Kim, B Bao, ... Journal of Crohn's and Colitis 18 (Supplement_1), i49-i50, 2024 | | 2024 |
Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence R Savić, J Yang, S Koplev, MC An, PL Patel, RN O’Brien, BN Dubose, ... Cell reports 42 (11), 2023 | 2 | 2023 |
Isoform-resolved transcriptome of the human preimplantation embryo D Torre, NJ Francoeur, Y Kalma, I Gross Carmel, BS Melo, G Deikus, ... Nature Communications 14 (1), 6902, 2023 | 6 | 2023 |
Peripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV2 Infection P Jayaraman, M Rajagopal, I Paranjpe, L Liharska, M Suarez-Farinas, ... medRxiv, 2023 | | 2023 |