Targeting DHODH reveals therapeutic opportunities in ATRA-resistant acute promyelocytic leukemia T Yang, X Shi, S Li, Z Zhao, J Wang, P Yu, H Li, R Wang, Z Chen Biomedicine & Pharmacotherapy 166, 115314, 2023 | | 2023 |
Insight into the relationship between the photostability and molecular structure of rhodamine dyes Y Liu, S Liu, R Miao, L Sun, Z Zhang, F Chen, J Zhang, S Li, B Tian Tetrahedron, 133664, 2023 | 2 | 2023 |
G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders TS Wong, G Li, S Li, W Gao, G Chen, S Gan, M Zhang, H Li, S Wu, Y Du Signal Transduction and Targeted Therapy 8 (1), 177, 2023 | 22 | 2023 |
Leflunomide treatment for patients hospitalised with COVID-19: DEFEAT-COVID randomised controlled trial I Kralj-Hans, K Li, A Wesek, A Lamorgese, F Omar, K Ranasinghe, ... BMJ open 13 (4), e068179, 2023 | 1 | 2023 |
Computational methods for scaffold hopping X Chen, R Miao, L Zhang, Z Yuan, H Li, S Li Privileged Scaffolds in Drug Discovery, 931-948, 2023 | | 2023 |
SwinOCSR: end-to-end optical chemical structure recognition using a Swin Transformer Z Xu, J Li, Z Yang, S Li, H Li Journal of Cheminformatics 14 (1), 1-13, 2022 | 27 | 2022 |
VRPharmer: bringing virtual reality into pharmacophore-based virtual screening with interactive exploration and realistic visualization S Liu, J Zhou, Z Feng, J Zhang, S Li, Z Jin, C Zhang, S Li, G He, H Li Bioinformatics 38 (21), 4953-4955, 2022 | | 2022 |
e-TSN: an interactive visual exploration platform for target–disease knowledge mapping from literature Z Feng, Z Shen, H Li, S Li Briefings in Bioinformatics 23 (6), bbac465, 2022 | 5 | 2022 |
Multi-modal chemical information reconstruction from images and texts for exploring the near-drug space J Wang, Z Shen, Y Liao, Z Yuan, S Li, G He, M Lan, X Qian, K Zhang, H Li Briefings in Bioinformatics 23 (6), bbac461, 2022 | 4 | 2022 |
Leflunomide Treatment for Patients Hospitalised with COVID-19: DEFEAT-COVID Randomised Controlled Trial K Li, A Wesek, S Li, S Sharma, ... | | 2022 |
A broad antiviral strategy: Inhibitors of human DHODH pave the way for host-targeting antivirals against emerging and re-emerging viruses Y Zheng, S Li, K Song, J Ye, W Li, Y Zhong, Z Feng, S Liang, Z Cai, K Xu Viruses 14 (5), 928, 2022 | 27 | 2022 |
Molecular docking for ligand-receptor binding process based on heterogeneous computing J Li, G Liu, Z Zhen, Z Shen, S Li, H Li Scientific Programming 2022, 1-13, 2022 | 10 | 2022 |
Dexlansoprazole prevents pulmonary artery hypertension by inhibiting pulmonary artery smooth muscle cell to fibroblast transition Q Jiao, F Zou, S Li, J Wang, Y Xiao, Z Guan, L Dong, J Tian, S Li, R Wang, ... American Journal of Translational Research 14 (8), 5466, 2022 | 1 | 2022 |
Design, Synthesis, and Structure–Activity Relationship Study of Potent MAPK11 Inhibitors M Gong, M Tu, H Sun, L Li, L Zhu, H Li, Z Zhao, S Li Molecules 27 (1), 203, 2022 | 3 | 2022 |
ePharmer: An integrated and graphical software for pharmacophore‐based virtual screening Y Mao, S Li, B Gong, L Lai, G He, H Li Journal of Computational Chemistry 42 (30), 2181-2195, 2021 | | 2021 |
A fast protein binding site comparison algorithm for proteome‐wide protein function prediction and drug repurposing S Li, C Cai, J Gong, X Liu, H Li Proteins: Structure, Function, and Bioinformatics 89 (11), 1541-1556, 2021 | 10 | 2021 |
Discovery, Optimization, and Structure–Activity Relationship Study of Novel and Potent RSK4 Inhibitors as Promising Agents for the Treatment of Esophageal Squamous Cell Carcinoma Y Yuan, J Xu, L Jiang, K Yu, Y Ge, M Li, H He, Q Niu, X Shi, L Fan, Z Chen, ... Journal of Medicinal Chemistry 64 (18), 13572-13587, 2021 | 6 | 2021 |
Mebhydrolin ameliorates glucose homeostasis in type 2 diabetic mice by functioning as a selective FXR antagonist T Zhao, J Wang, A He, S Wang, Y Chen, J Lu, J Lv, S Li, J Wang, M Qian, ... Metabolism 119, 154771, 2021 | 19 | 2021 |
Lipopolysaccharide preparation derived from Porphyromonas gingivalis induces a weaker immuno-inflammatory response in BV-2 microglial cells than Escherichia coli by … C Qiu, Z Yuan, Z He, H Chen, Y Liao, S Li, W Zhou, Z Song Frontiers in Cellular and Infection Microbiology 11, 606986, 2021 | 21 | 2021 |
Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of … F Zeng, S Li, G Yang, Y Luo, T Qi, Y Liang, T Yang, L Zhang, R Wang, ... Acta Pharmaceutica Sinica B 11 (3), 795-809, 2021 | 18 | 2021 |