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Melanie J Shears
Melanie J Shears
在 uw.edu 的电子邮件经过验证
标题
引用次数
年份
Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria
FN Watson, MJ Shears, AC Kalata, CJ Duncombe, AM Seilie, C Chavtur, ...
Scientific Reports 14 (1), 2881, 2024
2024
Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine
Z MacMillen, K Hatzakis, A Simpson, MJ Shears, F Watson, JH Erasmus, ...
npj Vaccines 9 (1), 12, 2024
22024
More time to kill: A longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria
N Yadav, C Parthiban, ZP Billman, BC Stone, FN Watson, K Zhou, ...
iScience 26 (12), 2023
2023
Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research
MJ Shears, RA Reynolds, CJ Duncombe, FN Watson, WJ Staubus, ...
Malaria Journal 22 (1), 379, 2023
12023
Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity
Y Zhu, J Ma, R Shen, J Lin, S Li, X Lu, JL Stelzel, J Kong, L Cheng, ...
Nature biomedical engineering, 1-17, 2023
112023
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness
S Mok, T Yeo, D Hong, MJ Shears, LS Ross, KE Ward, SK Dhingra, ...
Science Advances 9 (45), eadi2364, 2023
82023
Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates
MJ Shears, FN Watson, BC Stone, IC Talavera, C Parthiban, J Matsubara, ...
Vaccine 41 (38), 5494-5498, 2023
12023
Plasmodium knowlesi in pig-tailed macaques: a new model for malaria vaccine research
MJ Shears, RA Reynolds, CJ Duncombe, FN Watson, WJ Staubus, ...
2023
AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes
C Marques-da-Silva, B Poudel, RP Baptista, K Peissig, LS Hancox, ...
Proceedings of the National Academy of Sciences 120 (2), e2210181120, 2023
82023
Sex-specific differences in cytokine induction by the glycolipid adjuvant 7DW8-5 in mice
FN Watson, CJ Duncombe, AC Kalata, E Conrad, S Chakravarty, BKL Sim, ...
Biomolecules 13 (1), 8, 2022
12022
Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites
S Chakravarty, MJ Shears, ER James, U Rai, N Kc, S Conteh, LE Lambert, ...
Malaria Journal 21 (1), 247, 2022
72022
Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression
Y Zhu, R Shen, I Vuong, RA Reynolds, MJ Shears, ZC Yao, Y Hu, WJ Cho, ...
Nature communications 13 (1), 4282, 2022
412022
Multi-step Screening and Composition Optimization of Lipid Nanoparticles for Liver-targeted Plasmid DNA Delivery
Y Zhu, R Shen, I Vuong, RA Reynolds, MJ Shears, SC Murphy, HQ Mao
2022
Differential sex-specific immune responses following Prime-and-Trap vaccination alters protection against malaria in mice
CJ Duncombe, FN Watson, AC Kalata, MJ Shears, SC Murphy
The Journal of Immunology 208 (1_Supplement), 181.14-181.14, 2022
2022
Cryopreserved sporozoites with and without the glycolipid adjuvant 7DW8-5 protect in prime-and-trap malaria vaccination
FN Watson, MJ Shears, J Matsubara, AC Kalata, AM Seilie, IC Talavera, ...
The American Journal of Tropical Medicine and Hygiene 106 (4), 1227, 2022
112022
Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites
SE Lindner, KE Swearingen, MJ Shears, A Sebastian, MP Walker, ...
Nature communications 13 (1), 283, 2022
12022
GLYCOLIPID-ADJUVANTED RADIATION-ATTENUATED SPOROZOITES IMPROVES THE EFFICACY OF A HETEROLOGOUS PRIME-AND-TRAP MALARIA VACCINE
FN Watson, AC Kalata, MJ Shears, S Chakravarty, BK Sim, SL Hoffman, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 134-134, 2021
2021
EXPERIMENTAL INFECTION OF PIGTAILED MACAQUES WITH PLASMODIUM KNOWLESI MALARIA PARASITES
MJ Shears, R Reynolds, S Chakravarty, B Sim, K Lee, SL Hoffman, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 335-335, 2021
2021
Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver
C Marques-da-Silva, B Poudel, RP Baptista, K Peissig, LS Hancox, ...
Biorxiv, 2021.01. 28.427517, 2021
32021
Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models
MJ Shears, AM Seilie, B Kim Lee Sim, SL Hoffman, SC Murphy
Malaria Journal 19, 1-9, 2020
92020
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