Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria FN Watson, MJ Shears, AC Kalata, CJ Duncombe, AM Seilie, C Chavtur, ... Scientific Reports 14 (1), 2881, 2024 | | 2024 |
Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine Z MacMillen, K Hatzakis, A Simpson, MJ Shears, F Watson, JH Erasmus, ... npj Vaccines 9 (1), 12, 2024 | 2 | 2024 |
More time to kill: A longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria N Yadav, C Parthiban, ZP Billman, BC Stone, FN Watson, K Zhou, ... iScience 26 (12), 2023 | | 2023 |
Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research MJ Shears, RA Reynolds, CJ Duncombe, FN Watson, WJ Staubus, ... Malaria Journal 22 (1), 379, 2023 | 1 | 2023 |
Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity Y Zhu, J Ma, R Shen, J Lin, S Li, X Lu, JL Stelzel, J Kong, L Cheng, ... Nature biomedical engineering, 1-17, 2023 | 11 | 2023 |
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness S Mok, T Yeo, D Hong, MJ Shears, LS Ross, KE Ward, SK Dhingra, ... Science Advances 9 (45), eadi2364, 2023 | 8 | 2023 |
Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates MJ Shears, FN Watson, BC Stone, IC Talavera, C Parthiban, J Matsubara, ... Vaccine 41 (38), 5494-5498, 2023 | 1 | 2023 |
Plasmodium knowlesi in pig-tailed macaques: a new model for malaria vaccine research MJ Shears, RA Reynolds, CJ Duncombe, FN Watson, WJ Staubus, ... | | 2023 |
AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes C Marques-da-Silva, B Poudel, RP Baptista, K Peissig, LS Hancox, ... Proceedings of the National Academy of Sciences 120 (2), e2210181120, 2023 | 8 | 2023 |
Sex-specific differences in cytokine induction by the glycolipid adjuvant 7DW8-5 in mice FN Watson, CJ Duncombe, AC Kalata, E Conrad, S Chakravarty, BKL Sim, ... Biomolecules 13 (1), 8, 2022 | 1 | 2022 |
Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites S Chakravarty, MJ Shears, ER James, U Rai, N Kc, S Conteh, LE Lambert, ... Malaria Journal 21 (1), 247, 2022 | 7 | 2022 |
Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression Y Zhu, R Shen, I Vuong, RA Reynolds, MJ Shears, ZC Yao, Y Hu, WJ Cho, ... Nature communications 13 (1), 4282, 2022 | 41 | 2022 |
Multi-step Screening and Composition Optimization of Lipid Nanoparticles for Liver-targeted Plasmid DNA Delivery Y Zhu, R Shen, I Vuong, RA Reynolds, MJ Shears, SC Murphy, HQ Mao | | 2022 |
Differential sex-specific immune responses following Prime-and-Trap vaccination alters protection against malaria in mice CJ Duncombe, FN Watson, AC Kalata, MJ Shears, SC Murphy The Journal of Immunology 208 (1_Supplement), 181.14-181.14, 2022 | | 2022 |
Cryopreserved sporozoites with and without the glycolipid adjuvant 7DW8-5 protect in prime-and-trap malaria vaccination FN Watson, MJ Shears, J Matsubara, AC Kalata, AM Seilie, IC Talavera, ... The American Journal of Tropical Medicine and Hygiene 106 (4), 1227, 2022 | 11 | 2022 |
Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites SE Lindner, KE Swearingen, MJ Shears, A Sebastian, MP Walker, ... Nature communications 13 (1), 283, 2022 | 1 | 2022 |
GLYCOLIPID-ADJUVANTED RADIATION-ATTENUATED SPOROZOITES IMPROVES THE EFFICACY OF A HETEROLOGOUS PRIME-AND-TRAP MALARIA VACCINE FN Watson, AC Kalata, MJ Shears, S Chakravarty, BK Sim, SL Hoffman, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 134-134, 2021 | | 2021 |
EXPERIMENTAL INFECTION OF PIGTAILED MACAQUES WITH PLASMODIUM KNOWLESI MALARIA PARASITES MJ Shears, R Reynolds, S Chakravarty, B Sim, K Lee, SL Hoffman, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 335-335, 2021 | | 2021 |
Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver C Marques-da-Silva, B Poudel, RP Baptista, K Peissig, LS Hancox, ... Biorxiv, 2021.01. 28.427517, 2021 | 3 | 2021 |
Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models MJ Shears, AM Seilie, B Kim Lee Sim, SL Hoffman, SC Murphy Malaria Journal 19, 1-9, 2020 | 9 | 2020 |