| A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy L Ye, JJ Park, L Peng, Q Yang, RD Chow, MB Dong, SZ Lam, J Guo, ... Cell Metabolism 34 (4), 595-614. e14, 2022 | 100 | 2022 |
| A web tool for the design of prime-editing guide RNAs RD Chow, JS Chen, J Shen, S Chen Nature biomedical engineering 5 (2), 190-194, 2021 | 114 | 2021 |
| AAV-mediated delivery of a Sleeping Beauty transposon and an mRNA-encoded transposase for the engineering of therapeutic immune cells L Ye, SZ Lam, L Yang, K Suzuki, Y Zou, Q Lin, Y Zhang, P Clark, L Peng, ... Nature Biomedical Engineering 8 (2), 132-148, 2024 | 6 | 2024 |
| AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma RD Chow, CD Guzman, G Wang, F Schmidt, MW Youngblood, L Ye, ... Nature neuroscience 20 (10), 1329-1341, 2017 | 228 | 2017 |
| AAV-Mediated Direct In vivo CRISPR Screen in Glioblastoma S Chen, C Ryan, CD Guzman, RJ Platt US Patent App. 16/489,595, 2020 | | 2020 |
| Abstract B095: Mapping the genetic features of immune checkpoint responsiveness using AAV-CRISPR mediated in vivo screen G Wang, R Chow, Z Bai, L Ye, S Chen Cancer Immunology Research 7 (2_Supplement), B095-B095, 2019 | | 2019 |
| Acyl-CoA dehydrogenase drives heat adaptation by sequestering fatty acids DK Ma, Z Li, AY Lu, F Sun, S Chen, M Rothe, R Menzel, F Sun, HR Horvitz Cell 161 (5), 1152-1163, 2015 | 127 | 2015 |
| Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome X Ni, YE Zhang, N Negre, S Chen, M Long, KP White PLoS biology 10 (11), e1001420, 2012 | 75 | 2012 |
| Applications of CRISPR technology in cellular immunotherapy X Zhou, PA Renauer, L Zhou, SY Fang, S Chen Immunological Reviews 320 (1), 199-216, 2023 | 4 | 2023 |
| Biosynthesis, purification, and substrate specificity of severe acute respiratory syndrome coronavirus 3C-like proteinase K Fan, P Wei, Q Feng, S Chen, C Huang, L Ma, B Lai, J Pei, Y Liu, J Chen, ... Journal of Biological Chemistry 279 (3), 1637-1642, 2004 | 380 | 2004 |
| Bivalent mRNA vaccine booster induces robust antibody immunity against Omicron lineages BA. 2, BA. 2.12. 1, BA. 2.75 and BA. 5 Z Fang, VS Monteiro, AM Hahn, ND Grubaugh, C Lucas, S Chen Cell Discovery 8 (1), 108, 2022 | 27 | 2022 |
| Bivalent mRNA vaccine booster induces robust antibody immunity against Omicron subvariants BA. 2, BA. 2.12. 1 and BA. 5 Z Fang, S Chen bioRxiv, 2022.07. 19.500616, 2022 | | 2022 |
| Cancer CRISPR screens in vivo RD Chow, S Chen Trends in cancer 4 (5), 349-358, 2018 | 103 | 2018 |
| Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering MB Dong, K Tang, X Zhou, J Shen, K Chen, HR Kim, J Zhou, H Cao, ... bioRxiv, 2023.03. 14.532657, 2023 | 3 | 2023 |
| Compositions and methods comprising viral vector systems for multiplexed activation of endogenous genes as immunotherapy and viral-based immune-gene therapy S Chen, G Wang, RD Chow, F Zhang US Patent App. 17/771,202, 2022 | | 2022 |
| Compositions and Methods for Efficacy Enhancement of T-Cell Based Immunotherapy S Chen, M Dong US Patent App. 16/625,542, 2022 | | 2022 |
| Compositions and methods for engineering and selection of car t cells with desired phenotypes S Chen, X Dai, Y Du, J Park US Patent App. 18/041,504, 2023 | | 2023 |
| Compositions and Methods for Enhancement of Homology-Directed Repair Mediated Precise Gene Editing by Programming DNA Repair with a Single RNA-Guided Endonuclease S Chen, L Ye, C Wang, F Han US Patent App. 17/257,476, 2021 | | 2021 |
| Compositions and Methods for High-Throughput Activation Screening to Boost T Cell Effector Function S Chen, RD Chow, L Ye, M Dong, J Park, L Peng US Patent App. 17/268,928, 2021 | | 2021 |
| Compositions and Methods for Identification of Membrane Targets for Enhancement of T cell Activity Against Cancer S Chen, L Ye, J Park, M Dong, RD Chow US Patent App. 17/264,691, 2022 | | 2022 |
