关注
LAKSHMI REDDY PALAM
LAKSHMI REDDY PALAM
Pediatrics Department, Indiana University School of Medicine, Indianapolis, USA
在 iupui.edu 的电子邮件经过验证
标题
引用次数
年份
2011–RESISTANCE OF TET2 MUTANT PRELEUKEMIC STEM CELLS TO EXTRAPHYSIOLOGIC OXYGEN SHOCK PROVIDES POTENTIAL INSIGHT INTO THEIR GROWTH ADVANTAGE
A Aljoufi, J Ropa, S Cooper, B Ramdas, LR Palam, R Kapur, H Broxmeyer
Experimental Hematology 100, S32-S33, 2021
2021
3149–OBESITY INDUCED INFLAMMATION EXACERBATES CLONAL HEMATOPOIESIS
SK Pasupuleti, B Ramdas, SS Burns, LR Palam, R Kanumuri, R Kumar, ...
Experimental Hematology 124, S124, 2023
12023
Blimp1 prevents methylation of Foxp3 and loss of regulatory T cell identity at sites of inflammation
G Garg, A Muschaweckh, H Moreno, A Vasanthakumar, S Floess, ...
Cell reports 26 (7), 1854-1868. e5, 2019
1142019
Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response
S Dey, TD Baird, D Zhou, LR Palam, DF Spandau, RC Wek
Journal of Biological Chemistry 285 (43), 33165-33174, 2010
2802010
Combined Heterozygous Loss of Tet2 and Dnmt3a Along with Expression of Flt3ITD/WT results in Acute Myeloid Leukemia Which Responds to a Combination of FLT3 Inhibitor, APE1 …
B Ramdas, LR Palam, RS Mali, Z Cai, R Pandey, R Kapur
Blood 134, 3754, 2019
2019
Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits …
S Rangaraju, S Marino, GD Roodman, LD Cripe, B Ramdas, LR Palam, ...
Blood 134, 5051, 2019
2019
DNA Methyltransferase Protein Synthesis Is Reduced in CXXC Finger Protein 1–Deficient Embryonic Stem Cells
JS Butler, LR Palam, CM Tate, JR Sanford, RC Wek, DG Skalnik
DNA and cell biology 28 (5), 223-231, 2009
212009
Downregulation of Morrbid in Tet2-Deficient Preleukemic Cells Overcomes Resistance to Inflammatory Stress and Mitigates Clonal Hematopoiesis
Z Cai, J Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ...
Blood 132, 1288, 2018
12018
Driver mutations in leukemia promote disease pathogenesis through a combination of cell-autonomous and niche modulation
B Ramdas, RS Mali, LR Palam, R Pandey, Z Cai, SK Pasupuleti, ...
Stem cell reports 15 (1), 95-109, 2020
142020
Exploiting the proteasome to overcome RAS and WT1 mutation mediated resistance to FLT-3 inhibition in acute myeloid leukemia
S Rangaraju, SK Pasupuleti, S Marino, DN Petrusca, LD Cripe, B Ramdas, ...
Cancer Research 80 (16_Supplement), 800-800, 2020
2020
Identification of Beta-Catenin As a Novel Ubiquitin-Regulated Target of Combined Flβ3/Syk-and Proteasome Inhibitors for Interruption of LSC Signaling in Poor-Risk AML
S Rangaraju, S Marino, DN Petrusca, LD Cripe, KJ Sargent, ...
Blood 132, 3949, 2018
2018
Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells
B Ramdas, LD Yuen, LR Palam, R Patel, SK Pasupuleti, V Jideonwo, ...
Molecular Therapy 30 (7), 2505-2521, 2022
42022
Inhibition of inflammatory signaling in Tet2 mutant preleukemic cells mitigates stress-induced abnormalities and clonal hematopoiesis
Z Cai, JJ Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ...
Cell stem cell 23 (6), 833-849. e5, 2018
3082018
Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma
LR Palam, J Gore, KE Craven, JL Wilson, M Korc
Cell death & disease 6 (10), e1913-e1913, 2015
1232015
Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast
KA Staschke, S Dey, JM Zaborske, LR Palam, JN McClintick, T Pan, ...
Journal of Biological Chemistry 285 (22), 16893-16911, 2010
1452010
Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid …
LR Palam, B Ramdas, K Pickerell, R Kapur
Blood 134, 723, 2019
2019
Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway
LR Palam, B Ramdas, K Pickerell, SK Pasupuleti, R Kanumuri, ...
JCI insight 8 (9), 2023
32023
Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway
palam l
Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway
LR Palam, RS Mali, B Ramdas, SN Srivatsan, V Visconte, RV Tiu, ...
JCI insight 3 (4), 2018
232018
Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells
R Mali, HR Martin, B Ramdas, L Palam, V Visconte, T Ramon, ...
Blood 126 (23), 775, 2015
2015
系统目前无法执行此操作,请稍后再试。
文章 1–20