2011–RESISTANCE OF TET2 MUTANT PRELEUKEMIC STEM CELLS TO EXTRAPHYSIOLOGIC OXYGEN SHOCK PROVIDES POTENTIAL INSIGHT INTO THEIR GROWTH ADVANTAGE A Aljoufi, J Ropa, S Cooper, B Ramdas, LR Palam, R Kapur, H Broxmeyer Experimental Hematology 100, S32-S33, 2021 | | 2021 |
3149–OBESITY INDUCED INFLAMMATION EXACERBATES CLONAL HEMATOPOIESIS SK Pasupuleti, B Ramdas, SS Burns, LR Palam, R Kanumuri, R Kumar, ... Experimental Hematology 124, S124, 2023 | 1 | 2023 |
Blimp1 prevents methylation of Foxp3 and loss of regulatory T cell identity at sites of inflammation G Garg, A Muschaweckh, H Moreno, A Vasanthakumar, S Floess, ... Cell reports 26 (7), 1854-1868. e5, 2019 | 114 | 2019 |
Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response S Dey, TD Baird, D Zhou, LR Palam, DF Spandau, RC Wek Journal of Biological Chemistry 285 (43), 33165-33174, 2010 | 280 | 2010 |
Combined Heterozygous Loss of Tet2 and Dnmt3a Along with Expression of Flt3ITD/WT results in Acute Myeloid Leukemia Which Responds to a Combination of FLT3 Inhibitor, APE1 … B Ramdas, LR Palam, RS Mali, Z Cai, R Pandey, R Kapur Blood 134, 3754, 2019 | | 2019 |
Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits … S Rangaraju, S Marino, GD Roodman, LD Cripe, B Ramdas, LR Palam, ... Blood 134, 5051, 2019 | | 2019 |
DNA Methyltransferase Protein Synthesis Is Reduced in CXXC Finger Protein 1–Deficient Embryonic Stem Cells JS Butler, LR Palam, CM Tate, JR Sanford, RC Wek, DG Skalnik DNA and cell biology 28 (5), 223-231, 2009 | 21 | 2009 |
Downregulation of Morrbid in Tet2-Deficient Preleukemic Cells Overcomes Resistance to Inflammatory Stress and Mitigates Clonal Hematopoiesis Z Cai, J Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ... Blood 132, 1288, 2018 | 1 | 2018 |
Driver mutations in leukemia promote disease pathogenesis through a combination of cell-autonomous and niche modulation B Ramdas, RS Mali, LR Palam, R Pandey, Z Cai, SK Pasupuleti, ... Stem cell reports 15 (1), 95-109, 2020 | 14 | 2020 |
Exploiting the proteasome to overcome RAS and WT1 mutation mediated resistance to FLT-3 inhibition in acute myeloid leukemia S Rangaraju, SK Pasupuleti, S Marino, DN Petrusca, LD Cripe, B Ramdas, ... Cancer Research 80 (16_Supplement), 800-800, 2020 | | 2020 |
Identification of Beta-Catenin As a Novel Ubiquitin-Regulated Target of Combined Flβ3/Syk-and Proteasome Inhibitors for Interruption of LSC Signaling in Poor-Risk AML S Rangaraju, S Marino, DN Petrusca, LD Cripe, KJ Sargent, ... Blood 132, 3949, 2018 | | 2018 |
Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells B Ramdas, LD Yuen, LR Palam, R Patel, SK Pasupuleti, V Jideonwo, ... Molecular Therapy 30 (7), 2505-2521, 2022 | 4 | 2022 |
Inhibition of inflammatory signaling in Tet2 mutant preleukemic cells mitigates stress-induced abnormalities and clonal hematopoiesis Z Cai, JJ Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ... Cell stem cell 23 (6), 833-849. e5, 2018 | 308 | 2018 |
Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma LR Palam, J Gore, KE Craven, JL Wilson, M Korc Cell death & disease 6 (10), e1913-e1913, 2015 | 123 | 2015 |
Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast KA Staschke, S Dey, JM Zaborske, LR Palam, JN McClintick, T Pan, ... Journal of Biological Chemistry 285 (22), 16893-16911, 2010 | 145 | 2010 |
Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid … LR Palam, B Ramdas, K Pickerell, R Kapur Blood 134, 723, 2019 | | 2019 |
Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway LR Palam, B Ramdas, K Pickerell, SK Pasupuleti, R Kanumuri, ... JCI insight 8 (9), 2023 | 3 | 2023 |
Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway palam l | | |
Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway LR Palam, RS Mali, B Ramdas, SN Srivatsan, V Visconte, RV Tiu, ... JCI insight 3 (4), 2018 | 23 | 2018 |
Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells R Mali, HR Martin, B Ramdas, L Palam, V Visconte, T Ramon, ... Blood 126 (23), 775, 2015 | | 2015 |